Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells

por Robinson, Philip S., Thomas, Laura E., Abascal, Federico, Jung, Hyunchul, Harvey, Luke M. R., West, Hannah D., Olafsson, Sigurgeir, Lee, Bernard C. H., Coorens, Tim H. H., Lee-Six, Henry, Butlin, Laura, Lander, Nicola, Truscott, Rebekah, Sanders, Mathijs A., Lensing, Stefanie V., Buczacki, Simon J. A., ten Hoopen, Rogier, Coleman, Nicholas, Brunton-Sim, Roxanne, Rushbrook, Simon, Saeb-Parsy, Kourosh, Lalloo, Fiona, Campbell, Peter J., Martincorena, Iñigo, Sampson, Julian R., Stratton, Michael R.
Publicado 2022

Somatic mutation rates scale with lifespan across mammals

por Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim H. H., Sanders, Mathijs A., Lawson, Andrew R. J., Harvey, Luke M. R., Bhosle, Shriram, Jones, David, Alcantara, Raul E., Butler, Timothy M., Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W., Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D., Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan St. John, Gerstung, Moritz, Campbell, Peter J., Murchison, Elizabeth P., Stratton, Michael R., Martincorena, Iñigo
Publicado 2022