Molecular Dynamics Simulation of the Crystallizable Fragment of IgG1—Insights for the Design of Fcabs

por Lai, Balder, Hasenhindl, Christoph, Obinger, Christian, Oostenbrink, Chris
Publicado 2014

Engineered IgG1‐Fc – one fragment to bind them all

por Lobner, Elisabeth, Traxlmayr, Michael W., Obinger, Christian, Hasenhindl, Christoph
Publicado 2016

Design of a colicin E7 based chimeric zinc-finger nuclease

por Németh, Eszter, Schilli, Gabriella K., Nagy, Gábor, Hasenhindl, Christoph, Gyurcsik, Béla, Oostenbrink, Chris
Publicado 2014

Directed evolution of stabilized IgG1-Fc scaffolds by application of strong heat shock to libraries displayed on yeast

por Traxlmayr, Michael W., Faissner, Maximilian, Stadlmayr, Gerhard, Hasenhindl, Christoph, Antes, Bernhard, Rüker, Florian, Obinger, Christian
Publicado 2012

Construction of pH-sensitive Her2-binding IgG1-Fc by directed evolution

por Traxlmayr, Michael W, Lobner, Elisabeth, Hasenhindl, Christoph, Stadlmayr, Gerhard, Oostenbrink, Chris, Rüker, Florian, Obinger, Christian
Publicado 2014

Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc

por Hasenhindl, Christoph, Traxlmayr, Michael W., Wozniak-Knopp, Gordana, Jones, Phil C., Stadlmayr, Gerhard, Rüker, Florian, Obinger, Christian
Publicado 2013

Creating stable stem regions for loop elongation in Fcabs — Insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations

por Hasenhindl, Christoph, Lai, Balder, Delgado, Javier, Traxlmayr, Michael W., Stadlmayr, Gerhard, Rüker, Florian, Serrano, Luis, Oostenbrink, Chris, Obinger, Christian
Publicado 2014

Construction of a Stability Landscape of the CH3 Domain of Human IgG1 by Combining Directed Evolution with High Throughput Sequencing

por Traxlmayr, Michael W., Hasenhindl, Christoph, Hackl, Matthias, Stadlmayr, Gerhard, Rybka, Jakub D., Borth, Nicole, Grillari, Johannes, Rüker, Florian, Obinger, Christian
Publicado 2012