Novel tri-specific tribodies induce strong T cell activation and anti-tumor effects in vitro and in vivo

por Passariello, Margherita, Yoshioka, Asami, Takahashi, Kota, Hashimoto, Shu-ichi, Inoue, Toshikazu, Nakamura, Koji, De Lorenzo, Claudia
Publicado 2022

Novel Bi-Specific Immuno-Modulatory Tribodies Potentiate T Cell Activation and Increase Anti-Tumor Efficacy

por Passariello, Margherita, Yoshioka, Asami, Takahashi, Kota, Hashimoto, Shu-ichi, Rapuano Lembo, Rosa, Manna, Lorenzo, Nakamura, Koji, De Lorenzo, Claudia
Publicado 2022

Fast-tracking antibody maturation using a B cell-based display system

por Masuda, Hitomi, Sawada, Atsushi, Hashimoto, Shu-ichi, Tamai, Kanako, Lin, Ke-Yi, Harigai, Naoto, Kurosawa, Kohei, Ohta, Kunihiro, Seo, Hidetaka, Itou, Hiroshi
Publicado 2022

Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line

por Seo, Hidetaka, Masuda, Hitomi, Asagoshi, Kenjiro, Uchiki, Tomoaki, Kawata, Shigehisa, Sasaki, Goh, Yabuki, Takashi, Miyai, Shunsuke, Takahashi, Naoki, Hashimoto, Shu-ichi, Sawada, Atsushi, Takaiwa, Aki, Koyama, Chika, Tamai, Kanako, Kurosawa, Kohei, Lin, Ke-Yi, Ohta, Kunihiro, Nakazaki, Yukoh
Publicado 2020