Escaping ESKAPE resistance: in vitro and in silico studies of multifunctional carbamimidoyl-tethered indoles against antibiotic-resistant bacteria

por Gulia, Kanika, Hassan, Ahmed H. E., Lenhard, Justin R., Farahat, Abdelbasset A.
Publicado 2023

Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds

por Farag, Ahmed K., Hassan, Ahmed H. E., Ahn, Byung Sun, Park, Ki Duk, Roh, Eun Joo
Publicado 2019

Design, Rational Repurposing, Synthesis, In Vitro Evaluation, Homology Modeling and In Silico Study of Sulfuretin Analogs as Potential Antileishmanial Hit Compounds

por Hassan, Ahmed H.E., Phan, Trong-Nhat, Choi, Yeonwoo, Moon, Suyeon, No, Joo Hwan, Lee, Yong Sup
Publicado 2022

(1)H-NMR and (13)C-NMR dataset for some oxidative metabolites of CRA13 and their analogs

por Hassan, Ahmed H.E., Cho, Min Chang, Kim, Hye In, Yang, Ji Seul, Park, Kyung Tae, Lee, Yong Sup
Publicado 2018

Small Molecules Incorporating Privileged Amidine Moiety as Potential Hits Combating Antibiotic-Resistant Bacteria

por El-Sayed, Selwan M., Ahmed, Samar A., Gulia, Kanika, Lenhard, Justin R., Hassan, Ahmed H.E., Farahat, Abdelbasset A.
Publicado 2023

Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors

por El-Demerdash, Amr, Al-Karmalawy, Ahmed A., Abdel-Aziz, Tarek Mohamed, Elhady, Sameh S., Darwish, Khaled M., Hassan, Ahmed H. E.
Publicado 2021

Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In...

por Elkamhawy, Ahmed, Paik, Sora, Ali, Eslam M. H., Hassan, Ahmed H. E., Kang, So Jin, Lee, Kyeong, Roh, Eun Joo
Publicado 2022

Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development...

por Hassan, Ahmed H. E., Phan, Trong-Nhat, Yoon, Seolmin, Lee, Cheol Jung, Jeon, Hye Rim, Kim, Seung-Hwan, No, Joo Hwan, Lee, Yong Sup
Publicado 2021

Design, Synthesis, and Repurposing of Rosmarinic Acid-β-Amino-α-Ketoamide Hybrids as Antileishmanial Agents

por Hassan, Ahmed H.E., Bayoumi, Waleed A., El-Sayed, Selwan M., Phan, Trong-Nhat, Oh, Taegeun, Ham, Gyeongpyo, Mahmoud, Kazem, No, Joo Hwan, Lee, Yong Sup
Publicado 2023

AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells

por Gil, Hyo-Sun, Lee, Jeong-Hun, Farag, Ahmed K., Hassan, Ahmed H. E., Chung, Kyung-Sook, Choi, Jung-Hye, Roh, Eun-Joo, Lee, Kyung-Tae
Publicado 2021

KCP10043F Represses the Proliferation of Human Non-Small Cell Lung Cancer Cells by Caspase-Mediated Apoptosis via STAT3 Inactivation

por Lee, Jeong-Hun, Lee, Hwi-Ho, Ryu, Ki Deok, Kim, Misong, Ko, Dohyeong, Chung, Kyung-Sook, Hassan, Ahmed H.E., Lee, Seung Hyeun, Lee, Jae Yeol, Lee, Kyung-Tae
Publicado 2020

In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases

por Hassan, Ahmed H. E., El-Sayed, Selwan M., Yamamoto, Mizuki, Gohda, Jin, Matsumoto, Takehisa, Shirouzu, Mikako, Inoue, Jun-ichiro, Kawaguchi, Yasushi, Mansour, Reem M. A., Anvari, Abtin, Farahat, Abdelbasset A.
Publicado 2023

23-Hydroxyursolic Acid Isolated from the Stem Bark of Cussonia bancoensis Induces Apoptosis through Fas/Caspase-8-Dependent Pathway in HL-60 Human Promyelocytic Leukemia Cells

por Won, Jong-Heon, Chung, Kyung-Sook, Park, Eun-Young, Lee, Jeong-Hun, Choi, Jung-Hye, Tapondjou, Leon Azefack, Park, Hee-Juhn, Nomura, Masaaki, Hassan, Ahmed H.E., Lee, Kyung-Tae
Publicado 2018

Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase

por Hassan, Ahmed H. E., Oh, Yeon Il, Lee, Chae Hyeon, Kim, Yeon Ju, Cho, Soo Bin, Alam, Md. Maqusood, Park, Sang-Eun, Chung, Kyung-Sook, Lee, Kyung-Tae, Lee, Yong Sup
Publicado 2023

Design, Synthesis, In Vitro, and In Silico Studies of New N(5)-Substituted-pyrazolo[3,4-d]pyrimidinone Derivatives as Anticancer CDK2 Inhibitors

por Zaki, Waheed A., El-Sayed, Selwan M., Alswah, Mohamed, El-Morsy, Ahmed, Bayoumi, Ashraf H., Mayhoub, Abrahman S., Moustafa, Walaa H., Awaji, Aeshah A., Roh, Eun Joo, Hassan, Ahmed H.E., Mahmoud, Kazem
Publicado 2023

The Anti-Proliferative Activity of the Hybrid TMS-TMF-4f Compound Against Human Cervical Cancer Involves Apoptosis Mediated by STAT3 Inactivation

por Hong, Joo Young, Chung, Kyung-Sook, Shin, Ji-Sun, Lee, Jeong-Hun, Gil, Hyo-Sun, Lee, Hwi-Ho, Choi, Eunwoo, Choi, Jung-Hye, Hassan, Ahmed H.E., Lee, Yong Sup, Lee, Kyung-Tae
Publicado 2019

Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani

por Hassan, Ahmed H. E., Bayoumi, Waleed A., El-Sayed, Selwan M., Phan, Trong-Nhat, Kim, Yeon Ju, Lee, Chae Hyeon, Cho, Soo Bin, Oh, Taegeun, Ham, Gyeongpyo, Mahmoud, Kazem, No, Joo Hwan, Lee, Yong Sup
Publicado 2023

Positional scanning of natural product hispidol’s ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for managemen...

por Hassan, Ahmed H. E., Kim, Hyeon Jeong, Gee, Min Sung, Park, Jong-Hyun, Jeon, Hye Rim, Lee, Cheol Jung, Choi, Yeonwoo, Moon, Suyeon, Lee, Danbi, Lee, Jong Kil, Park, Ki Duk, Lee, Yong Sup
Publicado 2022

A Novel Hydroxyapatite/Vitamin B(12) Nanoformula for Treatment of Bone Damage: Preparation, Characterization, and Anti-Arthritic, Anti-Inflammatory, and Antioxidant Activities in C...

por Belal, Amany, Mahmoud, Rehab, Mohamed, Eman E., Farghali, Ahmed, Abo El-Ela, Fatma I., Gamal, Amr, Halfaya, Fatma Mohamed, Khaled, Esraa, Farahat, Abdelbasset A., Hassan, Ahmed H. E., Ghoneim, Mohammed M., Taha, Mohamed, Zaky, Mohamed Y.
Publicado 2023

Exploring the Antimicrobial Activity of Sodium Titanate Nanotube Biomaterials in Combating Bone Infections: An In Vitro and In Vivo Study

por Almalki, Atiah H., Hassan, Walid Hamdy, Belal, Amany, Farghali, Ahmed, Saleh, Romissaa M., Allah, Abeer Enaiet, Abdelwahab, Abdalla, Lee, Sangmin, Hassan, Ahmed H.E., Ghoneim, Mohammed M., Abdullah, Omeima, Mahmoud, Rehab, Abo El-Ela, Fatma I.
Publicado 2023