How Single Amino Acid Substitutions Can Disrupt a Protein Hetero-Dimer Interface: Computational and Experimental Studies of the LigAB Dioxygenase from Sphingobium sp. Strain SYK-6

por Rafalowski, Angelika, Hassan, Bakar A., Lou, Kate, Nguyen, Minh Chau, Taylor, Erika A.
Publicado 2023

Conserved Conformational Hierarchy across Functionally Divergent Glycosyltransferases of the GT-B Structural Superfamily as Determined from Microsecond Molecular Dynamics

por Ramirez-Mondragon, Carlos A., Nguyen, Megin E., Milicaj, Jozafina, Hassan, Bakar A., Tucci, Frank J., Muthyala, Ramaiah, Gao, Jiali, Taylor, Erika A., Sham, Yuk Y.
Publicado 2021

Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action

por Milicaj, Jozafina, Hassan, Bakar A., Cote, Joy M., Ramirez-Mondragon, Carlos A., Jaunbocus, Nadiya, Rafalowski, Angelika, Patel, Kaelan R., Castro, Colleen D., Muthyala, Ramaiah, Sham, Yuk Y., Taylor, Erika A.
Publicado 2022