Targeting mesothelin in ovarian cancer

por Ghafoor, Azam, Thomas, Anish, Hassan, Raffit
Publicado 2018

Panbinostat decreases cFLIP and enhances killing of cancer cells by immunotoxin LMB-100 by stimulating the extrinsic apoptotic pathway

por Liu, Xiu-Fen, Zhou, Qi, Hassan, Raffit, Pastan, Ira
Publicado 2017

In Vivo Imaging of Human Malignant Mesothelioma Grown Orthotopically in the Peritoneal Cavity of Nude Mice

por Feng, Mingqian, Zhang, Jingli, Anver, Miriam, Hassan, Raffit, Ho, Mitchell
Publicado 2011

Emerging Treatments for Malignant Pleural Mesothelioma: Where Are We Heading?

por Cantini, Luca, Hassan, Raffit, Sterman, Daniel H., Aerts, Joachim G. J. V.
Publicado 2020

Megakaryocytic Potentiating Factor and Mature Mesothelin Stimulate the Growth of a Lung Cancer Cell Line in the Peritoneal Cavity of Mice

por Zhang, Jingli, Bera, Tapan K., Liu, Wenhai, Du, Xing, Alewine, Christine, Hassan, Raffit, Pastan, Ira
Publicado 2014

New High Affinity Monoclonal Antibodies Recognize Non-Overlapping Epitopes On Mesothelin For Monitoring And Treating Mesothelioma

por Zhang, Yi-Fan, Phung, Yen, Gao, Wei, Kawa, Seiji, Hassan, Raffit, Pastan, Ira, Ho, Mitchell
Publicado 2015

Dual B- and T-cell de-immunization of recombinant immunotoxin targeting mesothelin with high cytotoxic activity

por Mazor, Ronit, Onda, Masanori, Park, Dong, Addissie, Selamawit, Xiang, Laiman, Zhang, Jingli, Hassan, Raffit, Pastan, Ira
Publicado 2016

Clinical experience with live-attenuated, double-deleted (LADD) listeria monocytogenes targeting mesothelin-expressing tumors

por Brockstedt, Dirk G, Le, Dung T, Hassan, Raffit, Murphy, Aimee, Grous, John, Dubensky, Thomas W, Jaffee, Elizabeth M
Publicado 2013

The Development and Characterization of a Human Mesothelioma In Vitro 3D Model to Investigate Immunotoxin Therapy

por Xiang, Xinran, Phung, Yen, Feng, Mingqian, Nagashima, Kunio, Zhang, Jingli, Broaddus, V. Courtney, Hassan, Raffit, FitzGerald, David, Ho, Mitchell
Publicado 2011

CA125 suppresses amatuximab immune-effector function and elevated serum levels are associated with reduced clinical response in first line mesothelioma patients

por Nicolaides, Nicholas C., Schweizer, Charles, Somers, Elizabeth B., Wang, Wenquan, Fernando, Shawn, Ross, Erin N., Grasso, Luigi, Hassan, Raffit, Kline, J. Bradford
Publicado 2018

Evaluation of the psychometric properties and minimally important difference of the MD Anderson Symptom Inventory for malignant pleural mesothelioma (MDASI-MPM)

por Mendoza, Tito R., Williams, Loretta A., Keating, Karen N., Siegel, Jonathan, Elbi, Cem, Nowak, Anna K., Hassan, Raffit, Cuffel, Brian, Cleeland, Charles S.
Publicado 2019

Anti-mesothelin vaccine CRS-207 with or without low-dose cyclophosphamide plus chemotherapy as front-line treatment for malignant pleural mesothelioma (MPM)

por Hassan, Raffit, Alley, Evan, Kindler, Hedy, Antonia, Scott, Jahan, Thierry, Thomas, Anish, Honarmand, Somayeh, Murphy, Aimee L, Grous, John J, Brockstedt, Dirk G
Publicado 2015

Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors

por Tomar, Sakshi, Zhang, Jingli, Khanal, Manakamana, Hong, Jessica, Venugopalan, Abhilash, Jiang, Qun, Sengupta, Manjistha, Miettinen, Markku, Li, Nan, Pastan, Ira, Ho, Mitchell, Hassan, Raffit
Publicado 2022

Safety and biodistribution of (111)In-amatuximab in patients with mesothelin expressing cancers using Single Photon Emission Computed Tomography-Computed Tomography (SPECT-CT) imag...

por Lindenberg, Liza, Thomas, Anish, Adler, Stephen, Mena, Esther, Kurdziel, Karen, Maltzman, Julia, Wallin, Bruce, Hoffman, Kimberly, Pastan, Ira, Paik, Chang Hum, Choyke, Peter, Hassan, Raffit
Publicado 2015

Phase 2 Study of Olaparib in Malignant Mesothelioma and Correlation of Efficacy With Germline or Somatic Mutations in BAP1 Gene

por Ghafoor, Azam, Mian, Idrees, Wagner, Cathy, Mallory, Yvonne, Agra, Maria Garcia, Morrow, Betsy, Wei, Jun S., Khan, Javed, Thomas, Anish, Sengupta, Manjistha, Steinberg, Seth M., Hassan, Raffit
Publicado 2021

Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies

por Zhan, Jingyu, Lin, Dong, Watson, Nathan, Esser, Lothar, Tang, Wai Kwan, Zhang, Alex, Liu, Xiufen, Hassan, Raffit, Gleinich, Anne, Shajahan, Asif, Azadi, Parastoo, Pastan, Ira, Xia, Di
Publicado 2023

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis

por Thomas, Anish, Chen, Yuanbin, Steinberg, Seth M., Luo, Ji, Pack, Svetlana, Raffeld, Mark, Abdullaev, Zied, Alewine, Christine, Rajan, Arun, Giaccone, Giuseppe, Pastan, Ira, Miettinen, Markku, Hassan, Raffit
Publicado 2015

Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma

por Kalra, Neetu, Zhang, Jingli, Thomas, Anish, Xi, Liqiang, Cheung, Mitchell, Talarchek, Jacqueline, Burkett, Sandra, Tsokos, Maria G, Chen, Yuanbin, Raffeld, Mark, Miettinen, Markku, Pastan, Ira, Testa, Joseph R, Hassan, Raffit
Publicado 2015

Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin

por Liu, Xiufen, Onda, Masanori, Watson, Nathan, Hassan, Raffit, Ho, Mitchell, Bera, Tapan K., Wei, Junxia, Chakraborty, Anirban, Beers, Richard, Zhou, Qi, Shajahan, Asif, Azadi, Parastoo, Zhan, Jingyu, Xia, Di, Pastan, Ira
Publicado 2022

Comprehensive immunohistochemical study of mesothelin (MSLN) using different monoclonal antibodies 5B2 and MN-1 in 1562 tumors with evaluation of its prognostic value in malignant...

por Inaguma, Shingo, Wang, Zengfeng, Lasota, Jerzy, Onda, Masanori, Czapiewski, Piotr, Langfort, Renata, Rys, Janusz, Szpor, Joanna, Waloszczyk, Piotr, Okoń, Krzysztof, Biernat, Wojciech, Ikeda, Hiroshi, Schrump, David S., Hassan, Raffit, Pastan, Ira, Miettinen, Markku
Publicado 2017