A score test for comparing cross-sectional survival data with a fraction of non-susceptible patients and its application in clinical immunology

por Jonas, Sarah Flora, Mbogning, Cyprien, Hässler, Signe, Broët, Philippe
Publicado 2017

A Genetic Association Test Accounting for Skewed X-Inactivation With Application to Biotherapy Immunogenicity in Patients With Autoimmune Diseases

por Hässler, Signe, Camilleri-Broët, Sophie, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Mariette, Xavier, Pallardy, Marc, Broët, Philippe
Publicado 2022

Machine learning predicts response to TNF inhibitors in rheumatoid arthritis: results on the ESPOIR and ABIRISK cohorts

por Bouget, Vincent, Duquesne, Julien, Hassler, Signe, Cournède, Paul-Henry, Fautrel, Bruno, Guillemin, Francis, Pallardy, Marc, Broët, Philippe, Mariette, Xavier, Bitoun, Samuel
Publicado 2022

Asparagine Endopeptidase Controls Anti-Influenza Virus Immune Responses through TLR7 Activation

por Maschalidi, Sophia, Hässler, Signe, Blanc, Fany, Sepulveda, Fernando E., Tohme, Mira, Chignard, Michel, van Endert, Peter, Si-Tahar, Mustapha, Descamps, Delphyne, Manoury, Bénédicte
Publicado 2012

Autoimmunity and cystatin SA 1 deficiency behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome

por Lindh, Emma, Brännström, Johan, Jones, Petra, Wermeling, Fredrik, Hässler, Signe, Betterle, Corrado, Garty, Ben Zion, Stridsberg, Mats, Herrmann, Björn, Karlsson, Mikael CI, Winqvist, Ola
Publicado 2012

A Machine Learning Approach for High-Dimensional Time-to-Event Prediction With Application to Immunogenicity of Biotherapies in the ABIRISK Cohort

por Duhazé, Julianne, Hässler, Signe, Bachelet, Delphine, Gleizes, Aude, Hacein-Bey-Abina, Salima, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Mariette, Xavier, Pallardy, Marc, Broët, Philippe
Publicado 2020

Assessing the effect of genetic markers on drug immunogenicity from a mechanistic model-based approach

por Duhazé, Julianne, Caubet, Miguel, Hässler, Signe, Bachelet, Delphine, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Gleizes, Aude, Hacein-Bey-Abina, Salima, Mariette, Xavier, Pallardy, Marc, Broët, Philippe
Publicado 2020

Definition of erythroid cell‐positive blood transcriptome phenotypes associated with severe respiratory syncytial virus infection

por Rinchai, Darawan, Altman, Matthew C., Konza, Oceane, Hässler, Signe, Martina, Federica, Toufiq, Mohammed, Garand, Mathieu, Kabeer, Basirudeen Syed Ahamed, Palucka, Karolina, Mejias, Asuncion, Ramilo, Octavio, Bedognetti, Davide, Mariotti‐Ferrandiz, Encarnita, Klatzmann, David, Chaussabel, Damien
Publicado 2020

Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia A

por Bachelet, Delphine, Albert, Thilo, Mbogning, Cyprien, Hässler, Signe, Zhang, Yuan, Schultze-Strasser, Stephan, Repessé, Yohann, Rayes, Julie, Pavlova, Anna, Pezeshkpoor, Behnaz, Liphardt, Kerstin, Davidson, Julie E., Hincelin-Méry, Agnès, Dönnes, Pierre, Lacroix-Desmazes, Sébastien, Königs, Christoph, Oldenburg, Johannes, Broët, Philippe
Publicado 2019

Response to Biologic Drugs in Patients With Rheumatoid Arthritis and Antidrug Antibodies

por Bitoun, Samuel, Hässler, Signe, Ternant, David, Szely, Natacha, Gleizes, Aude, Richez, Christophe, Soubrier, Martin, Avouac, Jérome, Brocq, Olivier, Sellam, Jérémie, de Vries, Niek, Huizinga, Tom W. J., Jury, Elizabeth C., Manson, Jessica J., Mauri, Claudia, Matucci, Andrea, Hacein Bey Abina, Salima, Mulleman, Denis, Pallardy, Marc, Broët, Philippe, Mariette, Xavier
Publicado 2023

Occurrence of Anti-Drug Antibodies against Interferon-Beta and Natalizumab in Multiple Sclerosis: A Collaborative Cohort Analysis

por Bachelet, Delphine, Hässler, Signe, Mbogning, Cyprien, Link, Jenny, Ryner, Malin, Ramanujam, Ryan, Auer, Michael, Hyldgaard Jensen, Poul Erik, Koch-Henriksen, Nils, Warnke, Clemens, Ingenhoven, Kathleen, Buck, Dorothea, Grummel, Verena, Lawton, Andy, Donnellan, Naoimh, Hincelin-Mery, Agnès, Sikkema, Dan, Pallardy, Marc, Kieseier, Bernd, Hemmer, Bernard, Hartung, Hans Peter, Soelberg Sorensen, Per, Deisenhammer, Florian, Dönnes, Pierre, Davidson, Julie, Fogdell-Hahn, Anna, Broët, Philippe
Publicado 2016

Clinical practice of analysis of anti-drug antibodies against interferon beta and natalizumab in multiple sclerosis patients in Europe: A descriptive study of test results

por Link, Jenny, Ramanujam, Ryan, Auer, Michael, Ryner, Malin, Hässler, Signe, Bachelet, Delphine, Mbogning, Cyprien, Warnke, Clemens, Buck, Dorothea, Hyldgaard Jensen, Poul Erik, Sievers, Claudia, Ingenhoven, Kathleen, Fissolo, Nicolas, Lindberg, Raija, Grummel, Verena, Donnellan, Naoimh, Comabella, Manuel, Montalban, Xavier, Kieseier, Bernd, Soelberg Sørensen, Per, Hartung, Hans-Peter, Derfuss, Tobias, Lawton, Andy, Sikkema, Dan, Pallardy, Marc, Hemmer, Bernhard, Deisenhammer, Florian, Broët, Philippe, Dönnes, Pierre, Davidson, Julie, Fogdell-Hahn, Anna
Publicado 2017

Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium

por Hässler, Signe, Bachelet, Delphine, Duhaze, Julianne, Szely, Natacha, Gleizes, Aude, Hacein-Bey Abina, Salima, Aktas, Orhan, Auer, Michael, Avouac, Jerôme, Birchler, Mary, Bouhnik, Yoram, Brocq, Olivier, Buck-Martin, Dorothea, Cadiot, Guillaume, Carbonnel, Franck, Chowers, Yehuda, Comabella, Manuel, Derfuss, Tobias, De Vries, Niek, Donnellan, Naoimh, Doukani, Abiba, Guger, Michael, Hartung, Hans-Peter, Kubala Havrdova, Eva, Hemmer, Bernhard, Huizinga, Tom, Ingenhoven, Kathleen, Hyldgaard-Jensen, Poul Erik, Jury, Elizabeth C., Khalil, Michael, Kieseier, Bernd, Laurén, Anna, Lindberg, Raija, Loercher, Amy, Maggi, Enrico, Manson, Jessica, Mauri, Claudia, Mohand Oumoussa, Badreddine, Montalban, Xavier, Nachury, Maria, Nytrova, Petra, Richez, Christophe, Ryner, Malin, Sellebjerg, Finn, Sievers, Claudia, Sikkema, Dan, Soubrier, Martin, Tourdot, Sophie, Trang, Caroline, Vultaggio, Alessandra, Warnke, Clemens, Spindeldreher, Sebastian, Dönnes, Pierre, Hickling, Timothy P., Hincelin Mery, Agnès, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Mariette, Xavier, Pallardy, Marc, Broët, Philippe
Publicado 2020