Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds

por Moraski, Garrett C., Deboosère, Nathalie, Marshall, Kate L., Weaver, Heath A., Vandeputte, Alexandre, Hastings, Courtney, Woolhiser, Lisa, Lenaerts, Anne J., Brodin, Priscille, Miller, Marvin J.
Publicado 2020

Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models

por Robertson, Gregory T., Scherman, Michael S., Bruhn, David F., Liu, Jiuyu, Hastings, Courtney, McNeil, Michael R., Butler, Michelle M., Bowlin, Terry L., Lee, Robin B., Lee, Richard E., Lenaerts, Anne J.
Publicado 2017

Comparative Analysis of Pharmacodynamics in the C3HeB/FeJ Mouse Tuberculosis Model for DprE1 Inhibitors TBA-7371, PBTZ169, and OPC-167832

por Robertson, Gregory T., Ramey, Michelle E., Massoudi, Lisa M., Carter, Claire L., Zimmerman, Matt, Kaya, Firat, Graham, Barbara G., Gruppo, Veronica, Hastings, Courtney, Woolhiser, Lisa K., Scott, Dashick W. L., Asay, Bryce C., Eshun-Wilson, Franceen, Maidj, Ekaterina, Podell, Brendan K., Vásquez, Joshua J., Lyons, Mike A., Dartois, Véronique, Lenaerts, Anne J.
Publicado 2021

Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA

por Xia, Yi, Zhou, Yasheen, Carter, David S, McNeil, Matthew B, Choi, Wai, Halladay, Jason, Berry, Pamela W, Mao, Weimin, Hernandez, Vincent, O'Malley, Theresa, Korkegian, Aaron, Sunde, Bjorn, Flint, Lindsay, Woolhiser, Lisa K, Scherman, Michael S, Gruppo, Veronica, Hastings, Courtney, Robertson, Gregory T, Ioerger, Thomas R, Sacchettini, Jim, Tonge, Peter J, Lenaerts, Anne J, Parish, Tanya, Alley, MRK
Publicado 2018

Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13

por Aggarwal, Anup, Parai, Maloy K., Shetty, Nishant, Wallis, Deeann, Woolhiser, Lisa, Hastings, Courtney, Dutta, Noton K., Galaviz, Stacy, Dhakal, Ramesh C., Shrestha, Rupesh, Wakabayashi, Shoko, Walpole, Chris, Matthews, David, Floyd, David, Scullion, Paul, Riley, Jennifer, Epemolu, Ola, Norval, Suzanne, Snavely, Thomas, Robertson, Gregory T., Rubin, Eric J., Ioerger, Thomas R., Sirgel, Frik A., van der Merwe, Ruben, van Helden, Paul D., Keller, Peter, Böttger, Erik C., Karakousis, Petros C., Lenaerts, Anne J., Sacchettini, James C.
Publicado 2017