A big score for RNA

por Hastings, Michelle L.
Publicado 2015

RNA therapeutics

por Hastings, Michelle L., Krainer, Adrian R.
Publicado 2023

Splice-switching antisense oligonucleotides as therapeutic drugs

por Havens, Mallory A., Hastings, Michelle L.
Publicado 2016

Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon

por Havens, Mallory A., Reich, Ashley A., Hastings, Michelle L.
Publicado 2014

Antisense oligonucleotide-mediated correction of CFTR splicing improves chloride secretion in cystic fibrosis patient-derived bronchial epithelial cells

por Michaels, Wren E, Bridges, Robert J, Hastings, Michelle L
Publicado 2020

A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2

por Jodelka, Francine M., Ebert, Allison D., Duelli, Dominik M., Hastings, Michelle L.
Publicado 2010

Biogenesis of mammalian microRNAs by a non-canonical processing pathway

por Havens, Mallory A., Reich, Ashley A., Duelli, Dominik M., Hastings, Michelle L.
Publicado 2012

Targeting SR Proteins Improves SMN Expression in Spinal Muscular Atrophy Cells

por Wee, Claribel D., Havens, Mallory A., Jodelka, Francine M., Hastings, Michelle L.
Publicado 2014

Comprehensive splice-site analysis using comparative genomics

por Sheth, Nihar, Roca, Xavier, Hastings, Michelle L., Roeder, Ted, Krainer, Adrian R., Sachidanandam, Ravi
Publicado 2006

Control of Pre-mRNA Splicing by the General Splicing Factors PUF60 and U2AF(65)

por Hastings, Michelle L., Allemand, Eric, Duelli, Dominik M., Myers, Michael P., Krainer, Adrian R.
Publicado 2007

Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis

por Michaels, Wren E., Pena-Rasgado, Cecilia, Kotaria, Rusudan, Bridges, Robert J., Hastings, Michelle L.
Publicado 2022

Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis

por Geraets, Ryan D., Koh, Seung yon, Hastings, Michelle L., Kielian, Tammy, Pearce, David A., Weimer, Jill M.
Publicado 2016

RNA localization and co‐translational interactions control RAB13 GTPase function and cell migration

por Moissoglu, Konstadinos, Stueland, Michael, Gasparski, Alexander N, Wang, Tianhong, Jenkins, Lisa M, Hastings, Michelle L, Mili, Stavroula
Publicado 2020

Viral-like TLR3 induction of cytokine networks and α-synuclein are reduced by complement C3 blockade in mouse brain

por Thomas, Ria, Connolly, Kyle J., Brekk, Oeystein R., Hinrich, Anthony J., Hastings, Michelle L., Isacson, Ole, Hallett, Penelope J.
Publicado 2023

Rescue of Outer Hair Cells with Antisense Oligonucleotides in Usher Mice Is Dependent on Age of Treatment

por Ponnath, Abhilash, Depreux, Frederic F., Jodelka, Francine M., Rigo, Frank, Farris, Hamilton E., Hastings, Michelle L., Lentz, Jennifer J.
Publicado 2017

Selective Release of MicroRNA Species from Normal and Malignant Mammary Epithelial Cells

por Pigati, Lucy, Yaddanapudi, Sree C. S., Iyengar, Ravi, Kim, Dong-Ja, Hearn, Steven A., Danforth, David, Hastings, Michelle L., Duelli, Dominik M.
Publicado 2010

Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice

por Korecka, Joanna A., Thomas, Ria, Hinrich, Anthony J., Moskites, Alyssa M., Macbain, Zach K., Hallett, Penelope J., Isacson, Ole, Hastings, Michelle L.
Publicado 2020

Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse

por Depreux, Frederic F., Wang, Lingyan, Jiang, Han, Jodelka, Francine M., Rosencrans, Robert F., Rigo, Frank, Lentz, Jennifer J., Brigande, John V., Hastings, Michelle L.
Publicado 2016

Searching for novel biomarkers using a mouse model of CLN3-Batten disease

por Timm, Derek, Cain, Jacob T., Geraets, Ryan D., White, Katherine A., Koh, Seung yon, Kielian, Tammy, Pearce, David A., Hastings, Michelle L., Weimer, Jill M.
Publicado 2018

Protracted CLN3 Batten disease in mice that genetically model an exon-skipping therapeutic approach

por Centa, Jessica L., Stratton, Matthew P., Pratt, Melissa A., Osterlund Oltmanns, Jenna R., Wallace, Douglas G., Miller, Steven A., Weimer, Jill M., Hastings, Michelle L.
Publicado 2023