A novel tissue-selective β2-adrenoceptor agonist with minimized cardiovascular effects, 5-HOB, attenuates neuropathic pain in mice

por Jourdain, Marie, Hatakeyama, Shinji
Publicado 2019

Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis

por Yamaura, Takeshi, Kasaoka, Tatsuhiko, Iijima, Naoko, Kimura, Masaaki, Hatakeyama, Shinji
Publicado 2019

Pharmacological profiling of a dual FAK/IGF-1R kinase inhibitor TAE226 in cellular and in vivo tumor models

por Fukami, Shigemi, Tomioka, Daisaku, Murakami, Yutaka, Honda, Toshiyuki, Hatakeyama, Shinji
Publicado 2019

Identification and characterization of a phenyl-thiazolyl-benzoic acid derivative as a novel RAR/RXR agonist

por Koshiishi, Chie, Kanazawa, Takanori, Vangrevelinghe, Eric, Honda, Toshiyuki, Hatakeyama, Shinji
Publicado 2019

ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments

por Hatakeyama, Shinji, Summermatter, Serge, Jourdain, Marie, Melly, Stefan, Minetti, Giulia C., Lach-Trifilieff, Estelle
Publicado 2016

Alleviation of High-Fat Diet-Induced Fatty Liver Damage in Group IVA Phospholipase A(2)-Knockout Mice

por Ii, Hiromi, Yokoyama, Naoki, Yoshida, Shintaro, Tsutsumi, Kae, Hatakeyama, Shinji, Sato, Takashi, Ishihara, Keiichi, Akiba, Satoshi
Publicado 2009

Degenerative joint disease induced by repeated intra-articular injections of monosodium urate crystals in rats as investigated by translational imaging

por Accart, Nathalie, Dawson, Janet, Obrecht, Michael, Lambert, Christian, Flueckiger, Manuela, Kreider, Julie, Hatakeyama, Shinji, Richards, Peter J., Beckmann, Nicolau
Publicado 2022

Clinical Classification of Cancer Cachexia: Phenotypic Correlates in Human Skeletal Muscle

por Johns, Neil, Hatakeyama, Shinji, Stephens, Nathan A., Degen, Martin, Degen, Simone, Frieauff, Wilfried, Lambert, Christian, Ross, James A., Roubenoff, Ronenn, Glass, David J., Jacobi, Carsten, Fearon, Kenneth C. H.
Publicado 2014

Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia

por Pettersen, Kristine, Andersen, Sonja, van der Veen, Anna, Nonstad, Unni, Hatakeyama, Shinji, Lambert, Christian, Lach‐Trifilieff, Estelle, Moestue, Siver, Kim, Jana, Grønberg, Bjørn Henning, Schilb, Alain, Jacobi, Carsten, Bjørkøy, Geir
Publicado 2019

TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells

por Otani, Hiroki, Yamamoto, Hiromasa, Takaoka, Munenori, Sakaguchi, Masakiyo, Soh, Junichi, Jida, Masaru, Ueno, Tsuyoshi, Kubo, Takafumi, Asano, Hiroaki, Tsukuda, Kazunori, Kiura, Katsuyuki, Hatakeyama, Shinji, Kawahara, Eiji, Naomoto, Yoshio, Miyoshi, Shinichiro, Toyooka, Shinichi
Publicado 2015

Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival

por Segatto, Marco, Fittipaldi, Raffaella, Pin, Fabrizio, Sartori, Roberta, Dae Ko, Kyung, Zare, Hossein, Fenizia, Claudio, Zanchettin, Gianpietro, Pierobon, Elisa Sefora, Hatakeyama, Shinji, Sperti, Cosimo, Merigliano, Stefano, Sandri, Marco, Filippakopoulos, Panagis, Costelli, Paola, Sartorelli, Vittorio, Caretti, Giuseppina
Publicado 2017

Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling

por Pettersen, Kristine, Andersen, Sonja, Degen, Simone, Tadini, Valentina, Grosjean, Joël, Hatakeyama, Shinji, Tesfahun, Almaz N., Moestue, Siver, Kim, Jana, Nonstad, Unni, Romundstad, Pål R., Skorpen, Frank, Sørhaug, Sveinung, Amundsen, Tore, Grønberg, Bjørn H., Strasser, Florian, Stephens, Nathan, Hoem, Dag, Molven, Anders, Kaasa, Stein, Fearon, Kenneth, Jacobi, Carsten, Bjørkøy, Geir
Publicado 2017