Oxygenation to improve cancer vaccines, adoptive cell transfer and blockade of immunological negative regulators

por Hatfield, Stephen M, Sitkovsky, Michail
Publicado 2015

Targeting Hypoxia-A2A Adenosinergic Immunosuppression of Antitumor T Cells During Cancer Immunotherapy

por Steingold, Joseph M., Hatfield, Stephen M.
Publicado 2020

Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells

por Sethumadhavan, Shalini, Silva, Murillo, Philbrook, Phaethon, Nguyen, Thao, Hatfield, Stephen M., Ohta, Akio, Sitkovsky, Michail V.
Publicado 2017

Targeted Elimination of Immunodominant B Cells Drives the Germinal Center Reaction toward Subdominant Epitopes

por Silva, Murillo, Nguyen, Thao H., Philbrook, Phaethon, Chu, Matthew, Sears, Olivia, Hatfield, Stephen, Abbott, Robert K., Kelsoe, Garnett, Sitkovsky, Michail V.
Publicado 2017

Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

por Sorrentino, Claudia, Hossain, Fokhrul, Rodriguez, Paulo C., Sierra, Rosa A., Pannuti, Antonio, Hatfield, Stephen, Osborne, Barbara A., Minter, Lisa M., Miele, Lucio, Morello, Silvana
Publicado 2019

Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

por Sorrentino, Claudia, Hossain, Fokhrul, Rodriguez, Paulo C., Sierra, Rosa A., Pannuti, Antonio, Hatfield, Stephen, Osborne, Barbara A., Minter, Lisa M., Miele, Lucio, Morello, Silvana
Publicado 2019

Fluorinated Adenosine A(2A) Receptor Antagonists Inspired by Preladenant as Potential Cancer Immunotherapeutics

por Yuan, Gengyang, Jankins, Tanner C., Patrick, Christopher G., Philbrook, Phaethon, Sears, Olivia, Hatfield, Stephen, Sitkovsky, Michail, Vasdev, Neil, Liang, Steven H., Ondrechen, Mary Jo, Pollastri, Michael P., Jones, Graham B.
Publicado 2017