S125: NON-GENETIC RESISTANCE TO MENIN INHIBITION IN AML IS REVERSIBLE BY PERTURBATION OF KAT6A

por Perner, Florian, Rahnamoun, Homa, Wenge, Daniela V., Xiong, Yijun, Apazidis, Athina, Anand, Disha, Hatton, Charlie, Wen, Yanhe, Gu, Shengqing, Liu, X Shirley, Xiao, Wenbin, Cai, Sheng F., Levine, Ross L., Mcgeehan, Gerard M., Armstrong, Scott A.
Publicado 2023

Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma

por Conery, Andrew R, Centore, Richard C, Neiss, Adrianne, Keller, Patricia J, Joshi, Shivangi, Spillane, Kerry L, Sandy, Peter, Hatton, Charlie, Pardo, Eneida, Zawadzke, Laura, Bommi-Reddy, Archana, Gascoigne, Karen E, Bryant, Barbara M, Mertz, Jennifer A, Sims, Robert J
Publicado 2016

Correction: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma

por Conery, Andrew R, Centore, Richard C, Neiss, Adrianne, Keller, Patricia J, Joshi, Shivangi, Spillane, Kerry L, Sandy, Peter, Hatton, Charlie, Pardo, Eneida, Zawadzke, Laura, Bommi-Reddy, Archana, Gascoigne, Karen E, Bryant, Barbara M, Mertz, Jennifer A, Sims, Robert J
Publicado 2016

An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition

por Egan, Brian, Yuan, Chih-Chi, Craske, Madeleine Lisa, Labhart, Paul, Guler, Gulfem D., Arnott, David, Maile, Tobias M., Busby, Jennifer, Henry, Chisato, Kelly, Theresa K., Tindell, Charles A., Jhunjhunwala, Suchit, Zhao, Feng, Hatton, Charlie, Bryant, Barbara M., Classon, Marie, Trojer, Patrick
Publicado 2016

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

por Lovejoy, Courtney A., Li, Wendi, Reisenweber, Steven, Thongthip, Supawat, Bruno, Joanne, de Lange, Titia, De, Saurav, Petrini, John H. J., Sung, Patricia A., Jasin, Maria, Rosenbluh, Joseph, Zwang, Yaara, Weir, Barbara A., Hatton, Charlie, Ivanova, Elena, Macconaill, Laura, Hanna, Megan, Hahn, William C., Lue, Neal F., Reddel, Roger R., Jiao, Yuchen, Kinzler, Kenneth, Vogelstein, Bert, Papadopoulos, Nickolas, Meeker, Alan K.
Publicado 2012

IKAROS and MENIN Coordinate Therapeutically Actionable Leukaemogenic Gene Expression in MLL-r Acute Myeloid Leukaemia

por Aubrey, Brandon J., Cutler, Jevon A., Bourgeois, Wallace, Donovan, Katherine A., Gu, Shengqing, Hatton, Charlie, Perlee, Sarah, Perner, Florian, Rahnamoun, Homa, Theall, Alexandra C. P., Henrich, Jill A., Zhu, Qian, Nowak, Radosław P., Kim, Young Joon, Parvin, Salma, Cremer, Anjali, Olsen, Sarah Naomi, Eleuteri, Nicholas A., Pikman, Yana, McGeehan, Gerard M., Stegmaier, Kimberly, Letai, Anthony, Fischer, Eric S., Liu, X. Shirley, Armstrong, Scott A.
Publicado 2022

Subtype-specific genomic alterations define new targets for soft tissue sarcoma therapy

por Barretina, Jordi, Taylor, Barry S., Banerji, Shantanu, Ramos, Alexis H., Lagos-Quintana, Mariana, DeCarolis, Penelope L., Shah, Kinjal, Socci, Nicholas D., Weir, Barbara A., Ho, Alan, Chiang, Derek Y., Reva, Boris, Mermel, Craig, Getz, Gad, Antipin, Yevgenyi, Beroukhim, Rameen, Major, John E., Hatton, Charlie, Nicoletti, Richard, Hanna, Megan, Sharpe, Ted, Fennell, Tim, Cibulskis, Kristian, Onofrio, Robert C., Saito, Tsuyoshi, Shukla, Neerav, Lau, Christopher, Nelander, Sven, Silver, Serena, Sougnez, Carrie, Viale, Agnes, Winckler, Wendy, Maki, Robert G., Garraway, Levi A., Lash, Alex, Greulich, Heidi, Root, David, Sellers, William R., Schwartz, Gary K., Antonescu, Cristina R., Lander, Eric S., Varmus, Harold E., Ladanyi, Marc, Sander, Chris, Meyerson, Matthew, Singer, Samuel
Publicado 2010