Using population isolates in genetic association studies

por Hatzikotoulas, Konstantinos, Gilly, Arthur, Zeggini, Eleftheria
Publicado 2014

Trans-ethnic study design approaches for fine-mapping

por Asimit, Jennifer L, Hatzikotoulas, Konstantinos, McCarthy, Mark, Morris, Andrew P, Zeggini, Eleftheria
Publicado 2016

Replication of HLA class II locus association with susceptibility to podoconiosis in three Ethiopian ethnic groups

por Gebresilase, Tewodros, Finan, Chris, Suveges, Daniel, Tessema, Tesfaye Sisay, Aseffa, Abraham, Davey, Gail, Hatzikotoulas, Konstantinos, Zeggini, Eleftheria, Newport, Melanie J., Tekola-Ayele, Fasil
Publicado 2021

A novel variant in GLIS3 is associated with osteoarthritis

por Casalone, Elisabetta, Tachmazidou, Ioanna, Zengini, Eleni, Hatzikotoulas, Konstantinos, Hackinger, Sophie, Suveges, Daniel, Steinberg, Julia, Rayner, Nigel William, Wilkinson, Jeremy Mark, Panoutsopoulou, Kalliope, Zeggini, Eleftheria
Publicado 2018

An epigenome-wide view of osteoarthritis in primary tissues

por Kreitmaier, Peter, Suderman, Matthew, Southam, Lorraine, Coutinho de Almeida, Rodrigo, Hatzikotoulas, Konstantinos, Meulenbelt, Ingrid, Steinberg, Julia, Relton, Caroline L., Wilkinson, J. Mark, Zeggini, Eleftheria
Publicado 2022

The Kinesin Gene KIF26B Modulates the Severity of Post-Traumatic Heterotopic Ossification

por Pickering, George A. E., Felix-Ilemhenbhio, Favour, Clark, Matthew J., Kocsy, Klaudia, Simpson, Jonathan, Bellantuono, Ilaria, Gartland, Alison, Wilkinson, Jeremy Mark, Hatzikotoulas, Konstantinos, Kiss-Toth, Endre
Publicado 2022

Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis

por Steinberg, Julia, Brooks, Roger A, Southam, Lorraine, Bhatnagar, Sahir, Roumeliotis, Theodoros I, Hatzikotoulas, Konstantinos, Zengini, Eleni, Wilkinson, J Mark, Choudhary, Jyoti S, McCaskie, Andrew W, Zeggini, Eleftheria
Publicado 2018

Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index

por Hartley, April, Sanderson, Eleanor, Granell, Raquel, Paternoster, Lavinia, Zheng, Jie, Smith, George Davey, Southam, Lorraine, Hatzikotoulas, Konstantinos, Boer, Cindy G, van Meurs, Joyce, Zeggini, Eleftheria, Gregson, Celia L, Tobias, Jon H
Publicado 2021

Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

por Hatzikotoulas, Konstantinos, Roposch, Andreas, Shah, Karan M., Clark, Matthew J., Bratherton, Selina, Limbani, Vasanti, Steinberg, Julia, Zengini, Eleni, Warsame, Kaltuun, Ratnayake, Madhushika, Tselepi, Maria, Schwartzentruber, Jeremy, Loughlin, John, Eastwood, Deborah M., Zeggini, Eleftheria, Wilkinson, J. Mark
Publicado 2018

Very low-depth whole-genome sequencing in complex trait association studies

por Gilly, Arthur, Southam, Lorraine, Suveges, Daniel, Kuchenbaecker, Karoline, Moore, Rachel, Melloni, Giorgio E M, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Ritchie, Graham, Schwartzentruber, Jeremy, Danecek, Petr, Kilian, Britt, Pollard, Martin O, Ge, Xiangyu, Tsafantakis, Emmanouil, Dedoussis, George, Zeggini, Eleftheria
Publicado 2019

Elevations in blood glucose before and after the appearance of islet autoantibodies in children

por Warncke, Katharina, Weiss, Andreas, Achenbach, Peter, von dem Berge, Thekla, Berner, Reinhard, Casteels, Kristina, Groele, Lidia, Hatzikotoulas, Konstantinos, Hommel, Angela, Kordonouri, Olga, Elding Larsson, Helena, Lundgren, Markus, Marcus, Benjamin A., Snape, Matthew D., Szypowska, Agnieszka, Todd, John A., Bonifacio, Ezio, Ziegler, Anette-G.
Publicado 2022

Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus

por Hackinger, Sophie, Trajanoska, Katerina, Styrkarsdottir, Unnur, Zengini, Eleni, Steinberg, Julia, Ritchie, Graham R.S., Hatzikotoulas, Konstantinos, Gilly, Arthur, Evangelou, Evangelos, Kemp, John P., Evans, David, Ingvarsson, Thorvaldur, Jonsson, Helgi, Thorsteinsdottir, Unnur, Stefansson, Kari, McCaskie, Andrew W., Brooks, Roger A., Wilkinson, Jeremy M., Rivadeneira, Fernando, Zeggini, Eleftheria
Publicado 2017

Identifying causal serum protein–cardiometabolic trait relationships using whole genome sequencing

por Png, Grace, Gerlini, Raffaele, Hatzikotoulas, Konstantinos, Barysenka, Andrei, Rayner, N William, Klarić, Lucija, Rathkolb, Birgit, Aguilar-Pimentel, Juan A, Rozman, Jan, Fuchs, Helmut, Gailus-Durner, Valerie, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Pietrzik, Claus, Wilson, James F, de Angelis, Martin Hrabe, Becker-Pauly, Christoph, Gilly, Arthur, Zeggini, Eleftheria
Publicado 2022

Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank

por Tachmazidou, Ioanna, Hatzikotoulas, Konstantinos, Southam, Lorraine, Esparza-Gordillo, Jorge, Haberland, Valeriia, Zheng, Jie, Johnson, Toby, Koprulu, Mine, Zengini, Eleni, Steinberg, Julia, Wilkinson, Jeremy M, Bhatnagar, Sahir, Hoffman, Joshua D, Buchan, Natalie, Süveges, Dániel, Yerges-Armstrong, Laura, Smith, George Davey, Gaunt, Tom R, Scott, Robert A, McCarthy, Linda C, Zeggini, Eleftheria
Publicado 2019

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

por Gilly, Arthur, Suveges, Daniel, Kuchenbaecker, Karoline, Pollard, Martin, Southam, Lorraine, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Bjornland, Thea, Waples, Ryan, Appel, Emil V. R., Casalone, Elisabetta, Melloni, Giorgio, Kilian, Britt, Rayner, Nigel W., Ntalla, Ioanna, Kundu, Kousik, Walter, Klaudia, Danesh, John, Butterworth, Adam, Barroso, Inês, Tsafantakis, Emmanouil, Dedoussis, George, Moltke, Ida, Zeggini, Eleftheria
Publicado 2018

Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

por Gilly, Arthur, Suveges, Daniel, Kuchenbaecker, Karoline, Pollard, Martin, Southam, Lorraine, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Bjornland, Thea, Waples, Ryan, Appel, Emil V. R., Casalone, Elisabetta, Melloni, Giorgio, Kilian, Britt, Rayner, Nigel W., Ntalla, Ioanna, Kundu, Kousik, Walter, Klaudia, Danesh, John, Butterworth, Adam, Barroso, Inês, Tsafantakis, Emmanouil, Dedoussis, George, Moltke, Ida, Zeggini, Eleftheria
Publicado 2018

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

por Tachmazidou, Ioanna, Dedoussis, George, Southam, Lorraine, Farmaki, Aliki-Eleni, Ritchie, Graham R. S., Xifara, Dionysia K., Matchan, Angela, Hatzikotoulas, Konstantinos, Rayner, Nigel W., Chen, Yuan, Pollin, Toni I., O’Connell, Jeffrey R., Yerges-Armstrong, Laura M., Kiagiadaki, Chrysoula, Panoutsopoulou, Kalliope, Schwartzentruber, Jeremy, Moutsianas, Loukas, Tsafantakis, Emmanouil, Tyler-Smith, Chris, McVean, Gil, Xue, Yali, Zeggini, Eleftheria
Publicado 2013

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis

por Zengini, Eleni, Hatzikotoulas, Konstantinos, Tachmazidou, Ioanna, Steinberg, Julia, Hartwig, Fernando P., Southam, Lorraine, Hackinger, Sophie, Boer, Cindy G., Styrkarsdottir, Unnur, Gilly, Arthur, Suveges, Daniel, Killian, Britt, Ingvarsson, Thorvaldur, Jonsson, Helgi, Babis, George C., McCaskie, Andrew, Uitterlinden, Andre G., van Meurs, Joyce B. J., Thorsteinsdottir, Unnur, Stefansson, Kari, Smith, George Davey, Wilkinson, Jeremy M., Zeggini, Eleftheria
Publicado 2018

Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants

por Panoutsopoulou, Kalliope, Hatzikotoulas, Konstantinos, Xifara, Dionysia Kiara, Colonna, Vincenza, Farmaki, Aliki-Eleni, Ritchie, Graham R. S., Southam, Lorraine, Gilly, Arthur, Tachmazidou, Ioanna, Fatumo, Segun, Matchan, Angela, Rayner, Nigel W., Ntalla, Ioanna, Mezzavilla, Massimo, Chen, Yuan, Kiagiadaki, Chrysoula, Zengini, Eleni, Mamakou, Vasiliki, Athanasiadis, Antonis, Giannakopoulou, Margarita, Kariakli, Vassiliki-Eirini, Nsubuga, Rebecca N., Karabarinde, Alex, Sandhu, Manjinder, McVean, Gil, Tyler-Smith, Chris, Tsafantakis, Emmanouil, Karaleftheri, Maria, Xue, Yali, Dedoussis, George, Zeggini, Eleftheria
Publicado 2014

The African Genome Variation Project shapes medical genetics in Africa

por Gurdasani, Deepti, Carstensen, Tommy, Tekola-Ayele, Fasil, Pagani, Luca, Tachmazidou, Ioanna, Hatzikotoulas, Konstantinos, Karthikeyan, Savita, Iles, Louise, Pollard, Martin O., Choudhury, Ananyo, Ritchie, Graham R. S., Xue, Yali, Asimit, Jennifer, Nsubuga, Rebecca N., Young, Elizabeth H., Pomilla, Cristina, Kivinen, Katja, Rockett, Kirk, Kamali, Anatoli, Doumatey, Ayo P., Asiki, Gershim, Seeley, Janet, Sisay-Joof, Fatoumatta, Jallow, Muminatou, Tollman, Stephen, Mekonnen, Ephrem, Ekong, Rosemary, Oljira, Tamiru, Bradman, Neil, Bojang, Kalifa, Ramsay, Michele, Adeyemo, Adebowale, Bekele, Endashaw, Motala, Ayesha, Norris, Shane A., Pirie, Fraser, Kaleebu, Pontiano, Kwiatkowski, Dominic, Tyler-Smith, Chris, Rotimi, Charles, Zeggini, Eleftheria, Sandhu, Manjinder S.
Publicado 2014