Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts

por Schneider, Ian C., Haugh, Jason M.
Publicado 2005

On the inference of ERK signaling dynamics from protein biosensor measurements

por Rahman, Shah Md. Toufiqur, Haugh, Jason M.
Publicado 2023

PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk

por Wang, Chun-Chao, Cirit, Murat, Haugh, Jason M
Publicado 2009

A Bipolar Clamp Mechanism for Activation of Jak-Family Protein Tyrosine Kinases

por Barua, Dipak, Faeder, James R., Haugh, Jason M.
Publicado 2009

PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk

por Wang, Chun-Chao, Cirit, Murat, Haugh, Jason M
Publicado 2011

Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132

por Cirit, Murat, Grant, Kyle G., Haugh, Jason M.
Publicado 2012

Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility

por Welf, Erik S., Johnson, Heath E., Haugh, Jason M.
Publicado 2013

Spatial Sensing in Fibroblasts Mediated by 3′ Phosphoinositides

por Haugh, Jason M., Codazzi, Franca, Teruel, Mary, Meyer, Tobias
Publicado 2000

A kinetic model of phospholipase C-γ1 linking structure-based insights to dynamics of enzyme autoinhibition and activation

por Nosbisch, Jamie L., Bear, James E., Haugh, Jason M.
Publicado 2022

Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism

por Welf, Erik S., Ahmed, Shoeb, Johnson, Heath E., Melvin, Adam T., Haugh, Jason M.
Publicado 2012

Stochastic Model of Integrin-Mediated Signaling and Adhesion Dynamics at the Leading Edges of Migrating Cells

por Cirit, Murat, Krajcovic, Matej, Choi, Colin K., Welf, Erik S., Horwitz, Alan F., Haugh, Jason M.
Publicado 2010

Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing

por Nosbisch, Jamie L., Rahman, Anisur, Mohan, Krithika, Elston, Timothy C., Bear, James E., Haugh, Jason M.
Publicado 2020

Isoform-specific optical activation of kinase function reveals p38-ERK signaling crosstalk

por Zhou, Wenyuan, Ryan, Amy, Janosko, Chasity P., Shoger, Karsen E., Haugh, Jason M., Gottschalk, Rachel A., Deiters, Alexander
Publicado 2023

Data‐driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

por Ahmed, Shoeb, Grant, Kyle G, Edwards, Laura E, Rahman, Anisur, Cirit, Murat, Goshe, Michael B, Haugh, Jason M
Publicado 2014

F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling

por Johnson, Heath E., King, Samantha J., Asokan, Sreeja B., Rotty, Jeremy D., Bear, James E., Haugh, Jason M.
Publicado 2015

GMFβ controls branched actin content and lamellipodial retraction in fibroblasts

por Haynes, Elizabeth M., Asokan, Sreeja B., King, Samantha J., Johnson, Heath E., Haugh, Jason M., Bear, James E.
Publicado 2015

Fibroblast Migration Is Regulated by Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein

por Ott, Laura E., Sung, Eui Jae, Melvin, Adam T., Sheats, Mary K., Haugh, Jason M., Adler, Kenneth B., Jones, Samuel L.
Publicado 2013