Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2

por Haure-Mirande, Jean-Vianney, Audrain, Mickael, Ehrlich, Michelle E., Gandy, Sam
Publicado 2022

Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma

por Dunkin, David, Iuga, Alina C., Mimouna, Sanda, Harris, Carolyn L., Haure-Mirande, Jean-Vianney, Bozec, Dominique, Yeretssian, Garabet, Dahan, Stephanie
Publicado 2018

Transcriptomic Changes Highly Similar to Alzheimer’s Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging

por Peng, Shouneng, Zeng, Lu, Haure-Mirande, Jean-Vianney, Wang, Minghui, Huffman, Derek M., Haroutunian, Vahram, Ehrlich, Michelle E., Zhang, Bin, Tu, Zhidong
Publicado 2021

Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice

por Audrain, Mickael, Haure‐Mirande, Jean‐Vianney, Mleczko, Justyna, Wang, Minghui, Griffin, Jennifer K., St George‐Hyslop, Peter H., Fraser, Paul, Zhang, Bin, Gandy, Sam, Ehrlich, Michelle E.
Publicado 2020

Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathol...

por Haure-Mirande, Jean-Vianney, Wang, Minghui, Audrain, Mickael, Fanutza, Tomas, Kim, Soong Ho, Heja, Szilvia, Readhead, Ben, Dudley, Joel T., Blitzer, Robert D., Schadt, Eric E., Zhang, Bin, Gandy, Sam, Ehrlich, Michelle E.
Publicado 2018

Correction: Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork mole...

por Haure-Mirande, Jean-Vianney, Wang, Minghui, Audrain, Mickael, Fanutza, Tomas, Kim, Soong Ho, Heja, Szilvia, Readhead, Ben, Dudley, Joel T., Blitzer, Robert D., Schadt, Eric E., Zhang, Bin, Gandy, Sam, Ehrlich, Michelle E.
Publicado 2018

Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer’s disease

por Castranio, Emilie L., Hasel, Philip, Haure-Mirande, Jean-Vianney, Ramirez Jimenez, Angie V., Hamilton, B. Wade, Kim, Rachel D., Glabe, Charles G., Wang, Minghui, Zhang, Bin, Gandy, Sam, Liddelow, Shane A., Ehrlich, Michelle E.
Publicado 2023

Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology

por Haure-Mirande, Jean-Vianney, Audrain, Mickael, Fanutza, Tomas, Kim, Soong Ho, Klein, William L., Glabe, Charles, Readhead, Ben, Dudley, Joel T., Blitzer, Robert D., Wang, Minghui, Zhang, Bin, Schadt, Eric E., Gandy, Sam, Ehrlich, Michelle E.
Publicado 2017

Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and stat...

por Audrain, Mickael, Haure-Mirande, Jean-Vianney, Wang, Minghui, Kim, Soong Ho, Fanutza, Tomas, Chakrabarty, Paramita, Fraser, Paul, St George-Hyslop, Peter H., Golde, Todd E., Blitzer, Robert D., Schadt, Eric E., Zhang, Bin, Ehrlich, Michelle E., Gandy, Sam
Publicado 2018

Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease

por Beckmann, Noam D., Lin, Wei-Jye, Wang, Minghui, Cohain, Ariella T., Charney, Alexander W., Wang, Pei, Ma, Weiping, Wang, Ying-Chih, Jiang, Cheng, Audrain, Mickael, Comella, Phillip H., Fakira, Amanda K., Hariharan, Siddharth P., Belbin, Gillian M., Girdhar, Kiran, Levey, Allan I., Seyfried, Nicholas T., Dammer, Eric B., Duong, Duc, Lah, James J., Haure-Mirande, Jean-Vianney, Shackleton, Ben, Fanutza, Tomas, Blitzer, Robert, Kenny, Eimear, Zhu, Jun, Haroutunian, Vahram, Katsel, Pavel, Gandy, Sam, Tu, Zhidong, Ehrlich, Michelle E., Zhang, Bin, Salton, Stephen R., Schadt, Eric E.
Publicado 2020

Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

por Wan, Ying-Wooi, Al-Ouran, Rami, Mangleburg, Carl G., Perumal, Thanneer M., Lee, Tom V., Allison, Katherine, Swarup, Vivek, Funk, Cory C., Gaiteri, Chris, Allen, Mariet, Wang, Minghui, Neuner, Sarah M., Kaczorowski, Catherine C., Philip, Vivek M., Howell, Gareth R., Martini-Stoica, Heidi, Zheng, Hui, Mei, Hongkang, Zhong, Xiaoyan, Kim, Jungwoo Wren, Dawson, Valina L., Dawson, Ted M., Pao, Ping-Chieh, Tsai, Li-Huei, Haure-Mirande, Jean-Vianney, Ehrlich, Michelle E., Chakrabarty, Paramita, Levites, Yona, Wang, Xue, Dammer, Eric B., Srivastava, Gyan, Mukherjee, Sumit, Sieberts, Solveig K., Omberg, Larsson, Dang, Kristen D., Eddy, James A., Snyder, Phil, Chae, Yooree, Amberkar, Sandeep, Wei, Wenbin, Hide, Winston, Preuss, Christoph, Ergun, Ayla, Ebert, Phillip J., Airey, David C., Mostafavi, Sara, Yu, Lei, Klein, Hans-Ulrich, Carter, Gregory W., Collier, David A., Golde, Todd E., Levey, Allan I., Bennett, David A., Estrada, Karol, Townsend, T. Matthew, Zhang, Bin, Schadt, Eric, De Jager, Philip L., Price, Nathan D., Ertekin-Taner, Nilüfer, Liu, Zhandong, Shulman, Joshua M., Mangravite, Lara M., Logsdon, Benjamin A.
Publicado 2020