Dual gene therapy with extracellular superoxide dismutase and catalase attenuates experimental optic neuritis

por Qi, Xiaoping, Hauswirth, William W., Guy, John
Publicado 2007

Efficient expression of self-complementary AAV in ganglion cells of the ex vivo primate retina

por Koilkonda, Rajeshwari D., Hauswirth, William W., Guy, John
Publicado 2009

Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice

por Chan, Fung, Hauswirth, William W., Wensel, Theodore G., Wilson, John H.
Publicado 2011

Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE

por Wang, Haibo, Kunz, Eric, Stoddard, Gregory J., Hauswirth, William W., Hartnett, M. Elizabeth
Publicado 2019

Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines

por Ryals, Renee C., Boye, Sanford L., Dinculescu, Astra, Hauswirth, William W., Boye, Shannon E.
Publicado 2011

Rescue of cone function in cone-only Nphp5 knockout mouse model with Leber congenital amaurosis phenotype

por Hanke-Gogokhia, Christin, Chiodo, Vince A., Hauswirth, William W., Frederick, Jeanne M., Baehr, Wolfgang
Publicado 2018

Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential

por Li, Qiuhong, Miller, Rehae, Han, Ping-Yang, Pang, Jijing, Dinculescu, Astra, Chiodo, Vince, Hauswirth, William W.
Publicado 2008

RNAi-Mediated Gene Suppression in a GCAP1(L151F) Cone-Rod Dystrophy Mouse Model

por Jiang, Li, Li, Tansy Z., Boye, Shannon E., Hauswirth, William W., Frederick, Jeanne M., Baehr, Wolfgang
Publicado 2013

Next-generation sequencing of mitochondrial targeted AAV transfer of human ND4 in mice

por Yu, Hong, Mehta, Arpit, Wang, Gaofeng, Hauswirth, William W., Chiodo, Vince, Boye, Sanford L., Guy, John
Publicado 2013

Small GTPases Rab8a and Rab11a Are Dispensable for Rhodopsin Transport in Mouse Photoreceptors

por Ying, Guoxin, Gerstner, Cecilia D., Frederick, Jeanne M., Boye, Sanford L., Hauswirth, William W., Baehr, Wolfgang
Publicado 2016

Rapid, widespread transduction of the murine myocardium using self-complementary Adeno-associated virus

por Andino, Lourdes M, Conlon, Thomas J, Porvasnik, Stacy L, Boye, Sanford L, Hauswirth, William W, Lewin, Alfred S
Publicado 2007

CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system

por Cabral Miranda, Felipe, Adão-Novaes, Juliana, Hauswirth, William W., Linden, Rafael, Petrs-Silva, Hilda, Chiarini, Luciana B.
Publicado 2015

Rescue of M-cone Function in Aged Opn1mw(−/−) Mice, a Model for Late-Stage Blue Cone Monochromacy

por Deng, Wen-Tao, Li, Jie, Zhu, Ping, Freedman, Beau, Smith, W. Clay, Baehr, Wolfgang, Hauswirth, William W.
Publicado 2019

A clinically viable approach to restoring visual function using optogenetic gene therapy

por Yan, Boyuan, Viswanathan, Suresh, Brodie, Scott E., Deng, Wen-Tao, Coleman, Kirsten E., Hauswirth, William W., Nirenberg, Sheila
Publicado 2023

Evaluation of Lateral Spread of Transgene Expression following Subretinal AAV–Mediated Gene Delivery in Dogs

por Bruewer, Ashlee R., Mowat, Freya M., Bartoe, Joshua T., Boye, Sanford L., Hauswirth, William W., Petersen-Jones, Simon M.
Publicado 2013

Inhibitor of Apoptosis-Stimulating Protein of p53 (iASPP) Is Required for Neuronal Survival after Axonal Injury

por Wilson, Ariel M., Chiodo, Vince A., Boye, Sanford L., Brecha, Nicholas C., Hauswirth, William W., Di Polo, Adriana
Publicado 2014

Disease mechanisms of X‐linked cone dystrophy caused by missense mutations in the red and green cone opsins

por Zhu, Ping, Dyka, Frank, Ma, Xiaojie, Yin, Ling, Yu, Heather, Baehr, Wolfgang, Hauswirth, William W., Deng, Wen‐Tao
Publicado 2021

Comparison of different gene-therapy methods to treat Leber hereditary optic neuropathy in a mouse model

por Velmurugan, Sindhu, Chou, Tsung-Han, Eastwood, Jeremy D., Porciatti, Vittorio, Liu, Yuan, Hauswirth, William W., Guy, John, Yu, Hong
Publicado 2023

Improvement in vision: a new goal for treatment of hereditary retinal degenerations

por Jacobson, Samuel G, Cideciyan, Artur V, Aguirre, Gustavo D, Roman, Alejandro J, Sumaroka, Alexander, Hauswirth, William W, Palczewski, Krzysztof
Publicado 2015

Cone Phosphodiesterase-6γ’ Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits

por Deng, Wen-Tao, Kolandaivelu, Saravanan, Dinculescu, Astra, Li, Jie, Zhu, Ping, Chiodo, Vince A., Ramamurthy, Visvanathan, Hauswirth, William W.
Publicado 2018