Effective Method of Purification of Betulin from Birch Bark: The Importance of Its Purity for Scientific and Medicinal Use

por Šiman, Pavel, Filipová, Alžběta, Tichá, Alena, Niang, Mohamed, Bezrouk, Aleš, Havelek, Radim
Publicado 2016

Flubendazole exhibits anti-glioblastoma effect by inhibiting STAT3 and promoting cell cycle arrest

por Vítovcová, Barbora, Skarková, Veronika, Havelek, Radim, Soukup, Jiří, Pande, Ananya, Caltová, Kateřina, Rudolf, Emil
Publicado 2023

Author Correction: Flubendazole exhibits anti-glioblastoma effect by inhibiting STAT3 and promoting cell cycle arrest

por Vítovcová, Barbora, Skarková, Veronika, Havelek, Radim, Soukup, Jiří, Pande, Ananya, Caltová, Kateřina, Rudolf, Emil
Publicado 2023

Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family

por Koutová, Darja, Maafi, Negar, Havelek, Radim, Opletal, Lubomír, Blunden, Gerald, Řezáčová, Martina, Cahlíková, Lucie
Publicado 2020

Disruption of Cell Adhesion and Cytoskeletal Networks by Thiol-Functionalized Silica-Coated Iron Oxide Nanoparticles

por Královec, Karel, Melounková, Lucie, Slováková, Marcela, Mannová, Nikola, Sedlák, Miloš, Bartáček, Jan, Havelek, Radim
Publicado 2020

The effect of sodium butyrate and cisplatin on expression of EMT markers

por Mrkvicova, Alena, Chmelarova, Marcela, Peterova, Eva, Havelek, Radim, Baranova, Ivana, Kazimirova, Petra, Rudolf, Emil, Rezacova, Martina
Publicado 2019

Pancracine, a Montanine-Type Amaryllidaceae Alkaloid, Inhibits Proliferation of A549 Lung Adenocarcinoma Cells and Induces Apoptotic Cell Death in MOLT-4 Leukemic Cells

por Koutová, Darja, Havelek, Radim, Peterová, Eva, Muthná, Darina, Královec, Karel, Breiterová, Kateřina, Cahlíková, Lucie, Řezáčová, Martina
Publicado 2021

The Effect of Chronic Exposure of Graphene Nanoplates on the Viability and Motility of A549 Cells

por Šestáková, Blanka, Schröterová, Ladislava, Bezrouk, Aleš, Čížková, Dana, Elkalaf, Moustafa, Havelek, Radim, Rudolf, Emil, Králová, Věra
Publicado 2022

Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities

por Ritomská, Aneta, Koutova, Darja, Křoustková, Jana, Královec, Karel, Muthná, Darina, Kuneš, Jiří, Nováková, Lucie, Havelek, Radim, Cahlíková, Lucie
Publicado 2023

The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis...

por SUCHA, LENKA, HROCH, MILOS, REZACOVA, MARTINA, RUDOLF, EMIL, HAVELEK, RADIM, SISPERA, LUDEK, CMIELOVA, JANA, KOHLEROVA, RENATA, BEZROUK, ALES, TOMSIK, PAVEL
Publicado 2013

Bersavine: A Novel Bisbenzylisoquinoline Alkaloid with Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells

por Koutova, Darja, Kulhava, Monika, Havelek, Radim, Majorosova, Martina, Královec, Karel, Habartova, Klara, Hošťálková, Anna, Opletal, Lubomír, Cahlikova, Lucie, Řezáčová, Martina
Publicado 2020

Amaryllidaceae Alkaloids of Different Structural Types from Narcissus L. cv. Professor Einstein and Their Cytotoxic Activity

por Breiterová, Kateřina, Koutová, Darja, Maříková, Jana, Havelek, Radim, Kuneš, Jiří, Majorošová, Martina, Opletal, Lubomír, Hošťálková, Anna, Jenčo, Jaroslav, Řezáčová, Martina, Cahlíková, Lucie
Publicado 2020

Multimodal Contrast Agent Enabling pH Sensing Based on Organically Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores

por Bui, Duong Thuy, Havelek, Radim, Královec, Karel, Kubíčková, Lenka, Kuličková, Jarmila, Matouš, Petr, Herynek, Vít, Kupčík, Jaroslav, Muthná, Darina, Řezanka, Pavel, Kaman, Ondřej
Publicado 2022

Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells

por Habartova, Klara, Havelek, Radim, Seifrtova, Martina, Kralovec, Karel, Cahlikova, Lucie, Chlebek, Jakub, Cermakova, Eva, Mazankova, Nadezda, Marikova, Jana, Kunes, Jiri, Novakova, Lucie, Rezacova, Martina
Publicado 2018

Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells

por Tripska, Katarina, Igreja Sá, Ivone Cristina, Vasinova, Martina, Vicen, Matej, Havelek, Radim, Eissazadeh, Samira, Svobodova, Zuzana, Vitverova, Barbora, Theuer, Charles, Bernabeu, Carmelo, Nachtigal, Petr
Publicado 2022

Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer’s Disease

por Kohelová, Eliška, Peřinová, Rozálie, Maafi, Negar, Korábečný, Jan, Hulcová, Daniela, Maříková, Jana, Kučera, Tomáš, Martínez González, Loreto, Hrabinova, Martina, Vorčáková, Katarina, Nováková, Lucie, De Simone, Angela, Havelek, Radim, Cahlíková, Lucie
Publicado 2019

Substituted Piperazines as Novel Potential Radioprotective Agents

por Filipova, Alzbeta, Marek, Jan, Havelek, Radim, Pejchal, Jaroslav, Jelicova, Marcela, Cizkova, Jana, Majorosova, Martina, Muckova, Lubica, Kucera, Tomas, Prchal, Lukas, Psotka, Miroslav, Zivna, Natalie, Koutova, Darja, Sinkorova, Zuzana, Rezacova, Martina, Tichy, Ales
Publicado 2020