Tofacitinib downregulates antiviral immune defence in keratinocytes and reduces T cell activation

por Hawerkamp, Heike C., Domdey, Alina, Radau, Lisa, Sewerin, Philipp, Oláh, Péter, Homey, Bernhard, Meller, Stephan
Publicado 2021

Retinoic Acid–Related Orphan Receptor α Is Required for Generation of Th2 Cells in Type 2 Pulmonary Inflammation

por Roberts, Joseph, Chevalier, Anne, Hawerkamp, Heike C., Yeow, Aoife, Matarazzo, Laura, Schwartz, Christian, Hams, Emily, Fallon, Padraic G.
Publicado 2023

Type I IFNs link skin-associated dysbiotic commensal bacteria to pathogenic inflammation and angiogenesis in rosacea

por Mylonas, Alessio, Hawerkamp, Heike C., Wang, Yichen, Chen, Jiaqi, Messina, Francesco, Demaria, Olivier, Meller, Stephan, Homey, Bernhard, Di Domizio, Jeremy, Mazzolai, Lucia, Hovnanian, Alain, Gilliet, Michel, Conrad, Curdin
Publicado 2023

Interleukin-26 activates macrophages and facilitates killing of Mycobacterium tuberculosis

por Hawerkamp, Heike C., van Geelen, Lasse, Korte, Jan, Di Domizio, Jeremy, Swidergall, Marc, Momin, Afaque A., Guzmán-Vega, Francisco J., Arold, Stefan T., Ernst, Joachim, Gilliet, Michel, Kalscheuer, Rainer, Homey, Bernhard, Meller, Stephan
Publicado 2020

Discovery and multi-parametric optimization of a high-affinity antibody against interleukin-25 with neutralizing activity in a mouse model of skin inflammation

por Bone, Ruth, Fennell, Brian J, Tam, Amy, Sheldon, Richard, Nocka, Karl, Varghese, Sreeja, Chang, Chew Shun, Hawerkamp, Heike C, Yeow, Aoife, Saunders, Sean P, Hams, Emily, Walsh, Patrick T, Cunningham, Orla, Fallon, Padraic G
Publicado 2022

von Willebrand factor links primary hemostasis to innate immunity

por Drakeford, Clive, Aguila, Sonia, Roche, Fiona, Hokamp, Karsten, Fazavana, Judicael, Cervantes, Mariana P., Curtis, Annie M., Hawerkamp, Heike C., Dhami, Sukhraj Pal Singh, Charles-Messance, Hugo, Hackett, Emer E., Chion, Alain, Ward, Soracha, Ahmad, Azaz, Schoen, Ingmar, Breen, Eamon, Keane, Joe, Murphy, Ross, Preston, Roger J. S., O’Sullivan, Jamie M., Sheedy, Frederick J., Fallon, Padraic, O’Donnell, James S.
Publicado 2022

Characterisation of the pro-inflammatory cytokine signature in severe COVID-19

por Hawerkamp, Heike C., Dyer, Adam H., Patil, Neha D., McElheron, Matt, O’Dowd, Niamh, O’Doherty, Laura, Mhaonaigh, Aisling Ui, George, Angel M., O’Halloran, Aisling M., Reddy, Conor, Kenny, Rose Anne, Little, Mark A., Martin-Loeches, Ignacio, Bergin, Colm, Kennelly, Sean P., Donnelly, Seamas C., Bourke, Nollaig M., Long, Aideen, Sui, Jacklyn, Doherty, Derek G., Conlon, Niall, Cheallaigh, Cliona Ni, Fallon, Padraic G.
Publicado 2023