Reconstitution of human pyroptotic cell death in Saccharomyces cerevisiae

por Ji, Yanhao, Hawkins, Christine J.
Publicado 2023

Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine

por Miles, Mark A, Hawkins, Christine J
Publicado 2017

Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways

por Miles, Mark A., Hawkins, Christine J.
Publicado 2018

In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations

por Miles, Mark A., Hawkins, Christine J.
Publicado 2020

Mutagenic Consequences of Sublethal Cell Death Signaling

por Hawkins, Christine J., Miles, Mark A.
Publicado 2021

Recent and Ongoing Research into Metastatic Osteosarcoma Treatments

por Harris, Michael A., Hawkins, Christine J.
Publicado 2022

Data on the DNA damaging and mutagenic potential of the BH3-mimetics ABT-263/Navitoclax and TW-37

por Green, Maja M., Shekhar, Tanmay M., Hawkins, Christine J.
Publicado 2016

Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9

por Ekert, Paul G., Silke, John, Hawkins, Christine J., Verhagen, Anne M., Vaux, David L.
Publicado 2001

Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate

por Kitevska, Tanja, Roberts, Sarah J., Pantaki-Eimany, Delara, Boyd, Sarah E., Scott, Fiona L., Hawkins, Christine J.
Publicado 2014

IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα

por Shekhar, Tanmay M., Miles, Mark A., Gupte, Ankita, Taylor, Scott, Tascone, Brianna, Walkley, Carl R., Hawkins, Christine J.
Publicado 2016

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites

por Silke, John, Hawkins, Christine J., Ekert, Paul G., Chew, Joanne, Day, Catherine L., Pakusch, Miha, Verhagen, Anne M., Vaux, David L.
Publicado 2002

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

por Ekert, Paul G., Read, Stuart H., Silke, John, Marsden, Vanessa S., Kaufmann, Hitto, Hawkins, Christine J., Gerl, Robert, Kumar, Sharad, Vaux, David L.
Publicado 2004

The Proteasome Inhibitor Ixazomib Inhibits the Formation and Growth of Pulmonary and Abdominal Osteosarcoma Metastases in Mice

por Harris, Michael A., Miles, Mark A., Shekhar, Tanmay M., Cerra, Carmelo, Georgy, Smitha R., Ryan, Stewart D., Cannon, Claire M., Hawkins, Christine J.
Publicado 2020

Caspase Inhibitors of the P35 Family Are More Active When Purified from Yeast than Bacteria

por Brand, Ingo L., Civciristov, Srgjan, Taylor, Nicole L., Talbo, Gert H., Pantaki-Eimany, Delara, Levina, Vita, Clem, Rollie J., Perugini, Matthew A., Kvansakul, Marc, Hawkins, Christine J.
Publicado 2012

Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice

por Shekhar, Tanmay M., Burvenich, Ingrid J. G., Harris, Michael A., Rigopoulos, Angela, Zanker, Damien, Spurling, Alex, Parker, Belinda S., Walkley, Carl R., Scott, Andrew M., Hawkins, Christine J.
Publicado 2019

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

por Vince, James E., Chau, Diep, Callus, Bernard, Wong, W. Wei-Lynn, Hawkins, Christine J., Schneider, Pascal, McKinlay, Mark, Benetatos, Christopher A., Condon, Stephen M., Chunduru, Srinivas K., Yeoh, George, Brink, Robert, Vaux, David L., Silke, John
Publicado 2008

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

por Samuel, Monisha, Fonseka, Pamali, Sanwlani, Rahul, Gangoda, Lahiru, Chee, Sing Ho, Keerthikumar, Shivakumar, Spurling, Alex, Chitti, Sai V., Zanker, Damien, Ang, Ching-Seng, Atukorala, Ishara, Kang, Taeyoung, Shahi, Sanjay, Marzan, Akbar L., Nedeva, Christina, Vennin, Claire, Lucas, Morghan C., Cheng, Lesley, Herrmann, David, Pathan, Mohashin, Chisanga, David, Warren, Sean C., Zhao, Kening, Abraham, Nidhi, Anand, Sushma, Boukouris, Stephanie, Adda, Christopher G., Jiang, Lanzhou, Shekhar, Tanmay M., Baschuk, Nikola, Hawkins, Christine J., Johnston, Amelia J., Orian, Jacqueline Monique, Hoogenraad, Nicholas J., Poon, Ivan K., Hill, Andrew F., Jois, Markandeya, Timpson, Paul, Parker, Belinda S., Mathivanan, Suresh
Publicado 2021