Serum C3 Enhances Complement Receptor 3-Mediated Phagocytosis of Borrelia burgdorferi

por Hawley, Kelly L., Olson, Chris M., Carreras-González, Ana, Navasa, Nicolás, Anguita, Juan
Publicado 2015

CD14 Targets Complement Receptor 3 to Lipid Rafts during Phagocytosis of Borrelia burgdorferi

por Hawley, Kelly L., Martín-Ruiz, Itziar, Iglesias-Pedraz, Juan M., Berwin, Brent, Anguita, Juan
Publicado 2013

Phagosomal TLR signaling upon Borrelia burgdorferi infection

por Cervantes, Jorge L., Hawley, Kelly L., Benjamin, Sarah J., Weinerman, Bennett, Luu, Stephanie M., Salazar, Juan C.
Publicado 2014

Inflammation and immune evasion coexist in Treponema pallidum–infected skin

por Trujillo, Rodolfo, Cervantes, Jorge, Hawley, Kelly L., Cruz, Adriana R., Babapoor, Sankhiros, Murphy, Michael, Dadras, Soheil S., Salazar, Juan C.
Publicado 2018

Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine

por Hawley, Kelly L., Montezuma-Rusca, Jairo M., Delgado, Kristina N., Singh, Navreeta, Uversky, Vladimir N., Caimano, Melissa J., Radolf, Justin D., Luthra, Amit
Publicado 2021

Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

por Benjamin, Sarah J., Hawley, Kelly L., Vera-Licona, Paola, La Vake, Carson J., Cervantes, Jorge L., Ruan, Yijun, Radolf, Justin D., Salazar, Juan C.
Publicado 2021

The RpoS Gatekeeper in Borrelia burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity

por Caimano, Melissa J., Groshong, Ashley M., Belperron, Alexia, Mao, Jialing, Hawley, Kelly L., Luthra, Amit, Graham, Danielle E., Earnhart, Christopher G., Marconi, Richard T., Bockenstedt, Linda K., Blevins, Jon S., Radolf, Justin D.
Publicado 2019

Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model...

por Luthra, Amit, Montezuma-Rusca, Jairo M., La Vake, Carson J., LeDoyt, Morgan, Delgado, Kristina N., Davenport, Timothy C., Fiel-Gan, Mary, Caimano, Melissa J., Radolf, Justin D., Hawley, Kelly L.
Publicado 2020

A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples

por Chen, Wentao, Luo, Hao, Zeng, Lihong, Pan, Yuying, Parr, Jonathan B., Jiang, Yinbo, Cunningham, Clark H., Hawley, Kelly L., Radolf, Justin D., Ke, Wujian, Ou, Jiangli, Yang, Jianjiang, Yang, Bin, Zheng, Heping
Publicado 2022

IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages

por Hawley, Kelly L., Cruz, Adriana R., Benjamin, Sarah J., La Vake, Carson J., Cervantes, Jorge L., LeDoyt, Morgan, Ramirez, Lady G., Mandich, Daniza, Fiel-Gan, Mary, Caimano, Melissa J., Radolf, Justin D., Salazar, Juan C.
Publicado 2017

Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp. pallidum, the Syphilis Spir...

por Kumar, Sanjiv, Caimano, Melissa J., Anand, Arvind, Dey, Abhishek, Hawley, Kelly L., LeDoyt, Morgan E., La Vake, Carson J., Cruz, Adriana R., Ramirez, Lady G., Paštěková, Lenka, Bezsonova, Irina, Šmajs, David, Salazar, Juan C., Radolf, Justin D.
Publicado 2018

Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0...

por Ferguson, Mary R., Delgado, Kristina N., McBride, Shannon, Orbe, Isabel C., La Vake, Carson J., Caimano, Melissa J., Mendez, Qiana, Moraes, Trevor F., Schryvers, Anthony B., Moody, M. Anthony, Radolf, Justin D., Weiner, Michael P., Hawley, Kelly L.
Publicado 2023

Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG(+)-Specific B-Cells in the Rabbit Model of Experimental Syphilis

por Delgado, Kristina N., Montezuma-Rusca, Jairo M., Orbe, Isabel C., Caimano, Melissa J., La Vake, Carson J., Luthra, Amit, Hennelly, Christopher M., Nindo, Fredrick N., Meyer, Jacob W., Jones, Letitia D., Parr, Jonathan B., Salazar, Juan C., Moody, M. Anthony, Radolf, Justin D., Hawley, Kelly L.
Publicado 2022

High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

por Lieberman, Nicole A. P., Armstrong, Thaddeus D., Chung, Benjamin, Pfalmer, Daniel, Hennelly, Christopher M., Haynes, Austin, Romeis, Emily, Wang, Qian-Qiu, Zhang, Rui-Li, Kou, Cai-Xia, Ciccarese, Giulia, Conte, Ivano Dal, Cusini, Marco, Drago, Francesco, Nakayama, Shu-ichi, Lee, Kenichi, Ohnishi, Makoto, Konda, Kelika A., Vargas, Silver K., Eguiluz, Maria, Caceres, Carlos F., Klausner, Jeffrey D., Mitja, Oriol, Rompalo, Anne, Mulcahy, Fiona, Hook, Edward W., Hoffman, Irving F., Matoga, Mitch M., Zheng, Heping, Yang, Bin, Lopez-Medina, Eduardo, Ramirez, Lady G., Radolf, Justin D., Hawley, Kelly L., Salazar, Juan C., Lukehart, Sheila A., Seña, Arlene C., Parr, Jonathan B., Giacani, Lorenzo, Greninger, Alexander L.
Publicado 2022