Role of Risk of Bias in Systematic Review for Chemical Risk Assessment: A Case Study in Understanding the Relationship Between Congenital Heart Defects and Exposures to Trichloroet...

por Wikoff, Daniele, Urban, Jon D., Harvey, Seneca, Haws, Laurie C.
Publicado 2018

Evaluation of Transcriptomic Responses in Livers of Mice Exposed to the Short-Chain PFAS Compound HFPO-DA

por Heintz, Melissa M., Chappell, Grace A., Thompson, Chad M., Haws, Laurie C.
Publicado 2022

Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans

por Heintz, Melissa M, Haws, Laurie C, Klaunig, James E, Cullen, John M, Thompson, Chad M
Publicado 2023

Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium

por Thompson, Chad M., Haws, Laurie C., Harris, Mark A., Gatto, Nicole M., Proctor, Deborah M.
Publicado 2011

Development of toxicity values and exposure estimates for tetrabromobisphenol A: application in a margin of exposure assessment

por Wikoff, Daniele, Thompson, Chad, Perry, Camarie, White, Matthew, Borghoff, Susan, Fitzgerald, Lauren, Haws, Laurie C.
Publicado 2015

Development of an oral reference dose for the perfluorinated compound GenX

por Thompson, Chad M., Fitch, Seneca E., Ring, Caroline, Rish, William, Cullen, John M., Haws, Laurie C.
Publicado 2019

Assessment of Mouse Liver Histopathology Following Exposure to HFPO-DA With Emphasis on Understanding Mechanisms of Hepatocellular Death

por Thompson, Chad M., Heintz, Melissa M., Wolf, Jeffrey C., Cheru, Roza, Haws, Laurie C., Cullen, John M.
Publicado 2023

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans

por Thompson, Chad M., Proctor, Deborah M., Suh, Mina, Haws, Laurie C., Kirman, Christopher R., Harris, Mark A.
Publicado 2013

Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks

por Chappell, Grace A., Thompson, Chad M., Wolf, Jeffrey C., Cullen, John M., Klaunig, James E., Haws, Laurie C.
Publicado 2020

Assessment of Cr(VI)-Induced Cytotoxicity and Genotoxicity Using High Content Analysis

por Thompson, Chad M., Fedorov, Yuriy, Brown, Daniel D., Suh, Mina, Proctor, Deborah M., Kuriakose, Liz, Haws, Laurie C., Harris, Mark A.
Publicado 2012

A chronic oral reference dose for hexavalent chromium-induced intestinal cancer†

por Thompson, Chad M, Kirman, Christopher R, Proctor, Deborah M, Haws, Laurie C, Suh, Mina, Hays, Sean M, Hixon, J Gregory, Harris, Mark A
Publicado 2014

Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment

por Thompson, Chad M., Rager, Julia E., Suh, Mina, Ring, Caroline L., Proctor, Deborah M., Haws, Laurie C., Fry, Rebecca C., Harris, Mark A.
Publicado 2016

Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium

por Thompson, Chad M., Wolf, Jeffrey C., McCoy, Alene, Suh, Mina, Proctor, Deborah M., Kirman, Christopher R., Haws, Laurie C., Harris, Mark A.
Publicado 2017

High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure

por Rager, Julia E., Ring, Caroline L., Fry, Rebecca C., Suh, Mina, Proctor, Deborah M., Haws, Laurie C., Harris, Mark A., Thompson, Chad M.
Publicado 2017

Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of A...

por Thompson, Chad M., Proctor, Deborah M., Suh, Mina, Haws, Laurie C., Hébert, Charles D., Mann, Jill F., Shertzer, Howard G., Hixon, J. Gregory, Harris, Mark A.
Publicado 2012

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin‐of‐exposure values for hexavalent chromium

por Thompson, Chad M., Kirman, Christopher R., Hays, Sean M., Suh, Mina, Harvey, Seneca E., Proctor, Deborah M., Rager, Julia E., Haws, Laurie C., Harris, Mark A.
Publicado 2017

Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium

por Thompson, Chad M., Proctor, Deborah M., Haws, Laurie C., Hébert, Charles D., Grimes, Sheila D., Shertzer, Howard G., Kopec, Anna K., Hixon, J.Gregory, Zacharewski, Timothy R., Harris, Mark A.
Publicado 2011

Synchrotron-Based Imaging of Chromium and γ-H2AX Immunostaining in the Duodenum Following Repeated Exposure to Cr(VI) in Drinking Water

por Thompson, Chad M., Seiter, Jennifer, Chappell, Mark A., Tappero, Ryan V., Proctor, Deborah M., Suh, Mina, Wolf, Jeffrey C., Haws, Laurie C., Vitale, Rock, Mittal, Liz, Kirman, Christopher R., Hays, Sean M., Harris, Mark A.
Publicado 2015