The receptor PTPRU is a redox sensitive pseudophosphatase

por Hay, Iain M., Fearnley, Gareth W., Rios, Pablo, Köhn, Maja, Sharpe, Hayley J., Deane, Janet E.
Publicado 2020

Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain

por Hay, Iain M, Mulholland, Katie E, Lai, Tiffany, Graham, Stephen C, Sharpe, Hayley J, Deane, Janet E
Publicado 2022

Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains

por Hay, Iain M., Shamin, Maria, Caroe, Eve R., Mohammed, Ahmed S.A., Svergun, Dmitri I., Jeffries, Cy M., Graham, Stephen C., Sharpe, Hayley J., Deane, Janet E.
Publicado 2022

The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell–cell adhesion

por Fearnley, Gareth W, Young, Katherine A, Edgar, James R, Antrobus, Robin, Hay, Iain M, Liang, Wei-Ching, Martinez-Martin, Nadia, Lin, WeiYu, Deane, Janet E, Sharpe, Hayley J
Publicado 2019

Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination

por Foster, William S., Lee, Jia Le, Thakur, Nazia, Newman, Joseph, Spencer, Alexandra J., Davies, Sophie, Woods, Danielle, Godfrey, Leila, Hay, Iain M., Innocentin, Silvia, Yam-Puc, Juan Carlos, Horner, Emily C., Sharpe, Hayley J., Thaventhiran, James E., Bailey, Dalan, Lambe, Teresa, Linterman, Michelle A.
Publicado 2022

Accelerated waning of the humoral response to COVID-19 vaccines in obesity

por van der Klaauw, Agatha A., Horner, Emily C., Pereyra-Gerber, Pehuén, Agrawal, Utkarsh, Foster, William S., Spencer, Sarah, Vergese, Bensi, Smith, Miriam, Henning, Elana, Ramsay, Isobel D., Smith, Jack A., Guillaume, Stephane M., Sharpe, Hayley J., Hay, Iain M., Thompson, Sam, Innocentin, Silvia, Booth, Lucy H., Robertson, Chris, McCowan, Colin, Kerr, Steven, Mulroney, Thomas E., O’Reilly, Martin J., Gurugama, Thevinya P., Gurugama, Lihinya P., Rust, Maria A., Ferreira, Alex, Ebrahimi, Soraya, Ceron-Gutierrez, Lourdes, Scotucci, Jacopo, Kronsteiner, Barbara, Dunachie, Susanna J., Klenerman, Paul, Park, Adrian J., Rubino, Francesco, Lamikanra, Abigail A., Stark, Hannah, Kingston, Nathalie, Estcourt, Lise, Harvala, Heli, Roberts, David J., Doffinger, Rainer, Linterman, Michelle A., Matheson, Nicholas J., Sheikh, Aziz, Farooqi, I. Sadaf, Thaventhiran, James E. D.
Publicado 2023