Oxygenating Biocatalysts for Hydroxyl Functionalisation in Drug Discovery and Development

por Charlton, Sacha N., Hayes, Martin A.
Publicado 2022

Oxalate Oxidase for In Situ H(2)O(2)‐Generation in Unspecific Peroxygenase‐Catalysed Drug Oxyfunctionalisations

por Romero, Elvira, Johansson, Magnus J., Cartwright, Jared, Grogan, Gideon, Hayes, Martin A.
Publicado 2022

P450(BM3) fused to phosphite dehydrogenase allows phosphite-driven selective oxidations

por Beyer, Nina, Kulig, Justyna K., Bartsch, Anette, Hayes, Martin A., Janssen, Dick B., Fraaije, Marco W.
Publicado 2016

Exploring the enzyme‐catalyzed synthesis of isotope labeled cyclopropanes

por Sardana, Malvika, Mühlfenzl, Kim S., Wenker, Sylvia T. M., Åkesson, Christian, Hayes, Martin A., Elmore, Charles S., Pithani, Subhash
Publicado 2022

Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis

por Nilsson, Anna, Peric, Alexandra, Strimfors, Marie, Goodwin, Richard J. A., Hayes, Martin A., Andrén, Per E., Hilgendorf, Constanze
Publicado 2017

Enzymatic Late‐Stage Modifications: Better Late Than Never

por Romero, Elvira, Jones, Bethan S., Hogg, Bethany N., Rué Casamajo, Arnau, Hayes, Martin A., Flitsch, Sabine L., Turner, Nicholas J., Schnepel, Christian
Publicado 2021

Biocatalysis in Drug Design: Engineered Reductive Aminases (RedAms) Are Used to Access Chiral Building Blocks with Multiple Stereocenters

por Casamajo, Arnau Rué, Yu, Yuqi, Schnepel, Christian, Morrill, Charlotte, Barker, Rhys, Levy, Colin W., Finnigan, James, Spelling, Victor, Westerlund, Kristina, Petchey, Mark, Sheppard, Robert J., Lewis, Richard J., Falcioni, Francesco, Hayes, Martin A., Turner, Nicholas J.
Publicado 2023

The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis

por Devine, Andrew J., Parnell, Alice E., Back, Catherine R., Lees, Nicholas R., Johns, Samuel T., Zulkepli, Ainul Z., Barringer, Rob, Zorn, Katja, Stach, James E. M., Crump, Matthew P., Hayes, Martin A., van der Kamp, Marc W., Race, Paul R., Willis, Christine L.
Publicado 2022