T-cell agonists in cancer immunotherapy

por Choi, Yeonjoo, Shi, Yaoyao, Haymaker, Cara L, Naing, Aung, Ciliberto, Gennaro, Hajjar, Joud
Publicado 2020

Delayed maturation of an IL-12–producing dendritic cell subset explains the early Th2 bias in neonatal immunity

por Lee, Hyun-Hee, Hoeman, Christine M., Hardaway, John C., Guloglu, F. Betul, Ellis, Jason S., Jain, Renu, Divekar, Rohit, Tartar, Danielle M., Haymaker, Cara L., Zaghouani, Habib
Publicado 2008

BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties

por Haymaker, Cara L, Wu, Richard C, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andrée, Chen, Jie Qing, Liu, Hui, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo G
Publicado 2015

Mechanisms Underlying Antigen-Specific Tolerance of Stable and Convertible Th17 Cells During Suppression of Autoimmune Diabetes

por Wan, Xiaoxiao, Guloglu, F. Betul, VanMorlan, Amie M., Rowland, Linda M., Jain, Renu, Haymaker, Cara L., Cascio, Jason A., Dhakal, Mermagya, Hoeman, Christine M., Tartar, Danielle M., Zaghouani, Habib
Publicado 2012

CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-β signaling

por Fix, Samantha M, Forget, Marie-Andrée, Sakellariou-Thompson, Donastas, Wang, Yunfei, Griffiths, Tamara M, Lee, Minjung, Haymaker, Cara L, Dominguez, Ana Lucía, Basar, Rafet, Reyes, Christopher, Kumar, Sanjay, Meyer, Larissa A, Hwu, Patrick, Bernatchez, Chantale, Jazaeri, Amir A
Publicado 2022

Phase II trial of neoadjuvant sitravatinib plus nivolumab in patients undergoing nephrectomy for locally advanced clear cell renal cell carcinoma

por Karam, Jose A., Msaouel, Pavlos, Haymaker, Cara L., Matin, Surena F., Campbell, Matthew T., Zurita, Amado J., Shah, Amishi Y., Wistuba, Ignacio I., Marmonti, Enrica, Duose, Dzifa Y., Parra, Edwin R., Soto, Luisa Maren Solis, Laberiano-Fernandez, Caddie, Lozano, Marisa, Abraham, Alice, Hallin, Max, Chin, Curtis D., Olson, Peter, Der-Torossian, Hirak, Yan, Xiaohong, Tannir, Nizar M., Wood, Christopher G.
Publicado 2023

Radiographic response to neoadjuvant therapy in pleural mesothelioma should serve as a guide for patient selection for cytoreductive operations

por Deboever, Nathaniel, Zhou, Nicolas, McGrail, Daniel J., Tomczak, Katarzyna, Oliva, Jacqueline L., Feldman, Hope A., Parra, Edwin, Zhang, Jianjun, Lee, Percy P., Antonoff, Mara B., Hofstetter, Wayne L., Mehran, Reza J., Rajaram, Ravi, Rice, David C., Roth, Jack A., Swisher, Stephen S., Vaporciyan, Ara A., Altan, Mehmet, Weissferdt, Annikka, Tsao, Anne S., Haymaker, Cara L., Sepesi, Boris
Publicado 2023

Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively i...

por Mitchell, Kyle G, Diao, Lixia, Karpinets, Tatiana, Negrao, Marcelo V, Tran, Hai T, Parra, Edwin R, Corsini, Erin M, Reuben, Alexandre, Federico, Lorenzo, Bernatchez, Chantale, Dejima, Hitoshi, Francisco-Cruz, Alejandro, Wang, Jing, Antonoff, Mara B, Vaporciyan, Ara A, Swisher, Stephen G, Cascone, Tina, Wistuba, Ignacio I, Heymach, John V, Gibbons, Don L, Zhang, Jianjun, Haymaker, Cara L, Sepesi, Boris
Publicado 2020

Phase II study of durvalumab (anti-PD-L1) and trametinib (MEKi) in microsatellite stable (MSS) metastatic colorectal cancer (mCRC)

por Johnson, Benny, Haymaker, Cara L, Parra, Edwin R, Soto, Luisa Maren Solis, Wang, Xuemei, Thomas, Jane V, Dasari, Arvind, Morris, Van K, Raghav, Kanwal, Vilar, Eduardo, Kee, Bryan K, Eng, Cathy, Parseghian, Christine M, Wolff, Robert A, Lee, Younghee, Lorenzini, Daniele, Laberiano-Fernandez, Caddie, Verma, Anuj, Lang, Wenhua, Wistuba, Ignacio I, Futreal, Andrew, Kopetz, Scott, Overman, Michael J
Publicado 2022

Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients with metastatic...

por Saberian, Chantal, Amaria, Rodabe N., Najjar, Amer M., Radvanyi, Laszlo G., Haymaker, Cara L., Forget, Marie-Andrée, Bassett, Roland L., Faria, Silvana C., Glitza, Isabella C., Alvarez, Enrique, Parshottam, Sapna, Prieto, Victor, Lizée, Gregory, Wong, Michael K., McQuade, Jennifer L., Diab, Adi, Yee, Cassian, Tawbi, Hussein A., Patel, Sapna, Shpall, Elizabeth J., Davies, Michael A., Hwu, Patrick, Bernatchez, Chantale
Publicado 2021

Hallmarks of Resistance to Immune-Checkpoint Inhibitors

por Karasarides, Maria, Cogdill, Alexandria P., Robbins, Paul B., Bowden, Michaela, Burton, Elizabeth M., Butterfield, Lisa H., Cesano, Alessandra, Hammer, Christian, Haymaker, Cara L., Horak, Christine E., McGee, Heather M., Monette, Anne, Rudqvist, Nils-Petter, Spencer, Christine N., Sweis, Randy F., Vincent, Benjamin G., Wennerberg, Erik, Yuan, Jianda, Zappasodi, Roberta, Lucey, Vanessa M. Hubbard, Wells, Daniel K., LaVallee, Theresa
Publicado 2022

Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes

por Shah, Parin, Forget, Marie-Andrée, Frank, Meredith L, Jiang, Peixin, Sakellariou-Thompson, Donastas, Federico, Lorenzo, Khairullah, Roohussaba, Neutzler, Chantal Alexia, Wistuba, Ignacio, Chow, Chi-Wan B, Long, Yan, Fujimoto, Junya, Lin, Shiaw-Yih, Maitra, Anirban, Negrao, Marcelo V, Mitchell, Kyle Gregory, Weissferdt, Annikka, Vaporciyan, Ara A, Cascone, Tina, Roth, Jack A, Zhang, Jianjun, Sepesi, Boris, Gibbons, Don L, Heymach, John V, Haymaker, Cara L, McGrail, Daniel J, Reuben, Alexandre, Bernatchez, Chantale
Publicado 2022

Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set

por Roszik, Jason, Haydu, Lauren E., Hess, Kenneth R., Oba, Junna, Joon, Aron Y., Siroy, Alan E., Karpinets, Tatiana V., Stingo, Francesco C., Baladandayuthapani, Veera, Tetzlaff, Michael T., Wargo, Jennifer A., Chen, Ken, Forget, Marie-Andrée, Haymaker, Cara L., Chen, Jie Qing, Meric-Bernstam, Funda, Eterovic, Agda K., Shaw, Kenna R., Mills, Gordon B., Gershenwald, Jeffrey E., Radvanyi, Laszlo G., Hwu, Patrick, Futreal, P. Andrew, Gibbons, Don L., Lazar, Alexander J., Bernatchez, Chantale, Davies, Michael A., Woodman, Scott E.
Publicado 2016

Multi-modal molecular programs regulate melanoma cell state

por Andrews, Miles C., Oba, Junna, Wu, Chang-Jiun, Zhu, Haifeng, Karpinets, Tatiana, Creasy, Caitlin A., Forget, Marie-Andrée, Yu, Xiaoxing, Song, Xingzhi, Mao, Xizeng, Robertson, A. Gordon, Romano, Gabriele, Li, Peng, Burton, Elizabeth M., Lu, Yiling, Sloane, Robert Szczepaniak, Wani, Khalida M., Rai, Kunal, Lazar, Alexander J., Haydu, Lauren E., Bustos, Matias A., Shen, Jianjun, Chen, Yueping, Morgan, Margaret B., Wargo, Jennifer A., Kwong, Lawrence N., Haymaker, Cara L., Grimm, Elizabeth A., Hwu, Patrick, Hoon, Dave S. B., Zhang, Jianhua, Gershenwald, Jeffrey E., Davies, Michael A., Futreal, P. Andrew, Bernatchez, Chantale, Woodman, Scott E.
Publicado 2022