Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study

por Haynes, Austin M., Giacani, Lorenzo, Mayans, Marti Vall, Ubals, Maria, Nieto, Carles, Pérez-Mañá, Clara, Quintó, Llorenç, Romeis, Emily, Mitjà, Oriol
Publicado 2021

Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum

por Haynes, Austin M., Fernandez, Mark, Romeis, Emily, Mitjà, Oriol, Konda, Kelika A., Vargas, Silver K., Eguiluz, Maria, Caceres, Carlos F., Klausner, Jeffrey D., Giacani, Lorenzo
Publicado 2021

Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws

por Giacani, Lorenzo, Bernstein, Lawrence R., Haynes, Austin M., Godornes, B. Charmie, Ciccarese, Giulia, Drago, Francesco, Parodi, Aurora, Valdevit, Sefora, Anselmi, Luca, Tomasini, Carlo Francesco, Baca, Arthur M.
Publicado 2019

Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure

por Lin, Michelle J., Haynes, Austin M., Addetia, Amin, Lieberman, Nicole A. P., Phung, Quynh, Xie, Hong, Nguyen, Tien V., Molini, Barbara J., Lukehart, Sheila A., Giacani, Lorenzo, Greninger, Alexander L.
Publicado 2021

Investigation of syphilis immunology and Treponema pallidum subsp. pallidum biology to improve clinical management and design a broadly protective vaccine: study protocol

por Osias, Ethan, Hung, Phoebe, Giacani, Lorenzo, Stafylis, Chrysovalantis, Konda, Kelika A., Vargas, Silver K., Reyes-Díaz, E. Michael, Comulada, W. Scott, Haake, David A., Haynes, Austin M., Caceres, Carlos F., Klausner, Jeffrey D.
Publicado 2020

Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar

por Lieberman, Nicole A. P., Lin, Michelle J., Xie, Hong, Shrestha, Lasata, Nguyen, Tien, Huang, Meei-Li, Haynes, Austin M., Romeis, Emily, Wang, Qian-Qiu, Zhang, Rui-Li, Kou, Cai-Xia, Ciccarese, Giulia, Dal Conte, Ivano, Cusini, Marco, Drago, Francesco, Nakayama, Shu-ichi, Lee, Kenichi, Ohnishi, Makoto, Konda, Kelika A., Vargas, Silver K., Eguiluz, Maria, Caceres, Carlos F., Klausner, Jeffrey D., Mitjà, Oriol, Rompalo, Anne, Mulcahy, Fiona, Hook, Edward W., Lukehart, Sheila A., Casto, Amanda M., Roychoudhury, Pavitra, DiMaio, Frank, Giacani, Lorenzo, Greninger, Alexander L.
Publicado 2021