In Vitro Maturation of Dopaminergic Neurons Derived from Mouse Embryonic Stem Cells: Implications for Transplantation

por Watmuff, Bradley, Pouton, Colin W., Haynes, John M.
Publicado 2012

Nuclear Transporter IPO13 Is Central to Efficient Neuronal Differentiation

por Gajewska, Katarzyna A., Haynes, John M., Jans, David A.
Publicado 2022

TGFβ3, dibutyryl cAMP and a notch inhibitor modulate phenotype late in stem cell-derived dopaminergic neuron maturation

por Sibuea, Shanti, Ho, Joan K., Pouton, Colin W., Haynes, John M.
Publicado 2023

DNA-Dependent Protein Kinase Is a Context Dependent Regulator of Lmx1a and Midbrain Specification

por Hunt, Cameron P., Fabb, Stewart A., Pouton, Colin W., Haynes, John M.
Publicado 2013

Characterization of forebrain neurons derived from late-onset Huntington's disease human embryonic stem cell lines

por Niclis, Jonathan C., Pinar, Anita, Haynes, John M., Alsanie, Walaa, Jenny, Robert, Dottori, Mirella, Cram, David S.
Publicado 2013

Inhibition of β-catenin dependent WNT signalling upregulates the transcriptional repressor NR0B1 and downregulates markers of an A9 phenotype in human embryonic stem cell-derived d...

por Haynes, John M., Sibuea, Shanti M., Aguiar, Alita A., Li, Fangwei, Ho, Joan K., Pouton, Colin W.
Publicado 2021

Human pluripotent stem cell derived midbrain PITX3(eGFP/w) neurons: a versatile tool for pharmacological screening and neurodegenerative modeling

por Watmuff, Bradley, Hartley, Brigham J., Hunt, Cameron P. J., Fabb, Stewart A., Pouton, Colin W., Haynes, John M.
Publicado 2015

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

por Niclis, Jonathan C., Gantner, Carlos W., Hunt, Cameron P.J., Kauhausen, Jessica A., Durnall, Jennifer C., Haynes, John M., Pouton, Colin W., Parish, Clare L., Thompson, Lachlan H.
Publicado 2017

Enhancing the Antipsychotic Effect of Risperidone by Increasing Its Binding Affinity to Serotonin Receptor via Picric Acid: A Molecular Dynamics Simulation

por Alhomrani, Majid, Alsanie, Walaa F., Alamri, Abdulhakeem S., Alyami, Hussain, Habeeballah, Hamza, Alkhatabi, Heba A., Felimban, Raed I., Haynes, John M., Shakya, Sonam, Raafat, Bassem M., Refat, Moamen S., Gaber, Ahmed
Publicado 2022

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno‐Free Conditions Restore Motor Deficits in Parkinsonian Rodents

por Niclis, Jonathan C., Gantner, Carlos W., Alsanie, Walaa F., McDougall, Stuart J., Bye, Chris R., Elefanty, Andrew G., Stanley, Edouard G., Haynes, John M., Pouton, Colin W., Thompson, Lachlan H., Parish, Clare L.
Publicado 2016

A CX3CR1 Reporter hESC Line Facilitates Integrative Analysis of In-Vitro-Derived Microglia and Improved Microglia Identity upon Neuron-Glia Co-culture

por Grubman, Alexandra, Vandekolk, Teresa H., Schröder, Jan, Sun, Guizhi, Hatwell-Humble, Jessica, Chan, Jonathan, Oksanen, Minna, Lehtonen, Sarka, Hunt, Cameron, Koistinaho, Jari E., Nilsson, Susan K., Haynes, John M., Pouton, Colin W., Polo, Jose M.
Publicado 2020

Transcriptional signature in microglia associated with Aβ plaque phagocytosis

por Grubman, Alexandra, Choo, Xin Yi, Chew, Gabriel, Ouyang, John F., Sun, Guizhi, Croft, Nathan P., Rossello, Fernando J., Simmons, Rebecca, Buckberry, Sam, Landin, Dulce Vargas, Pflueger, Jahnvi, Vandekolk, Teresa H., Abay, Zehra, Zhou, Yichen, Liu, Xiaodong, Chen, Joseph, Larcombe, Michael, Haynes, John M., McLean, Catriona, Williams, Sarah, Chai, Siew Yeen, Wilson, Trevor, Lister, Ryan, Pouton, Colin W., Purcell, Anthony W., Rackham, Owen J. L., Petretto, Enrico, Polo, Jose M.
Publicado 2021

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

por Anderson, David J., Kaplan, David I., Bell, Katrina M., Koutsis, Katerina, Haynes, John M., Mills, Richard J., Phelan, Dean G., Qian, Elizabeth L., Leitoguinho, Ana Rita, Arasaratnam, Deevina, Labonne, Tanya, Ng, Elizabeth S., Davis, Richard P., Casini, Simona, Passier, Robert, Hudson, James E., Porrello, Enzo R., Costa, Mauro W., Rafii, Arash, Curl, Clare L., Delbridge, Lea M., Harvey, Richard P., Oshlack, Alicia, Cheung, Michael M., Mummery, Christine L., Petrou, Stephen, Elefanty, Andrew G., Stanley, Edouard G., Elliott, David A.
Publicado 2018