Staphylococcus aureus type I signal peptidase: essential or not essential, that’s the question

por Hazenbos, Wouter L., Skippington, Elizabeth, Tan, Man-Wah
Publicado 2017

Structural investigation of human S. aureus-targeting antibodies that bind wall teichoic acid

por Fong, Rina, Kajihara, Kimberly, Chen, Matthew, Hotzel, Isidro, Mariathasan, Sanjeev, Hazenbos, Wouter L.W., Lupardus, Patrick J.
Publicado 2018

Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging

por Zhou, Chenguang, Cai, Hao, Baruch, Amos, Lewin-Koh, Nicholas, Yang, Meng, Guo, Fengxun, Xu, Deming, Deng, Rong, Hazenbos, Wouter, Kamath, Amrita V.
Publicado 2019

167. A Phase 1b, Randomized, Double-blind, Placebo-controlled, Multiple-ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Patients...

por Lim, Jeremy, Lewin-Koh, Nicholas, Chu, Tom, Rymut, Sharon M, Berhanu, Aklile, Carrasco-Triguero, Montserrat, Rosenberger, Carrie C, Hazenbos, Wouter L, Miller, Loren G, Fowler, Vance G, Miro, Jose M, Couch, Jessica A, Peck, Melicent C
Publicado 2020

A Putative Bacterial ABC Transporter Circumvents the Essentiality of Signal Peptidase

por Morisaki, J. Hiroshi, Smith, Peter A., Date, Shailesh V., Kajihara, Kimberly K., Truong, Chau Linda, Modrusan, Zora, Yan, Donghong, Kang, Jing, Xu, Min, Shah, Ishita M., Mintzer, Robert, Kofoed, Eric M., Cheung, Tommy K., Arnott, David, Koehler, Michael F. T., Heise, Christopher E., Brown, Eric J., Tan, Man-Wah, Hazenbos, Wouter L. W.
Publicado 2016

Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate

por Kajihara, Kimberly K., Pantua, Homer, Hernandez-Barry, Hilda, Hazen, Meredith, Deshmukh, Kiran, Chiang, Nancy, Ohri, Rachana, Castellanos, Erick R., Martin, Lynn, Matsumoto, Marissa L., Payandeh, Jian, Storek, Kelly M., Schneider, Kellen, Smith, Peter A., Koehler, Michael F. T., Tsai, Siao Ping, Vandlen, Richard, Loyet, Kelly M., Nakamura, Gerald, Pillow, Thomas, Seshasayee, Dhaya, Kapadia, Sharookh B., Hazenbos, Wouter L. W.
Publicado 2021

Novel Staphylococcal Glycosyltransferases SdgA and SdgB Mediate Immunogenicity and Protection of Virulence-Associated Cell Wall Proteins

por Hazenbos, Wouter L. W., Kajihara, Kimberly K., Vandlen, Richard, Morisaki, J. Hiroshi, Lehar, Sophie M., Kwakkenbos, Mark J., Beaumont, Tim, Bakker, Arjen Q., Phung, Qui, Swem, Lee R., Ramakrishnan, Satish, Kim, Janice, Xu, Min, Shah, Ishita M., Diep, Binh An, Sai, Tao, Sebrell, Andrew, Khalfin, Yana, Oh, Angela, Koth, Chris, Lin, S. Jack, Lee, Byoung-Chul, Strandh, Magnus, Koefoed, Klaus, Andersen, Peter S., Spits, Hergen, Brown, Eric J., Tan, Man-Wah, Mariathasan, Sanjeev
Publicado 2013

A homogeneous high-DAR antibody–drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides

por Zacharias, Neelie, Podust, Vladimir N., Kajihara, Kimberly K., Leipold, Douglas, Del Rosario, Geoffrey, Thayer, Desiree, Dong, Emily, Paluch, Maciej, Fischer, David, Zheng, Kai, Lei, Corinna, He, Jintang, Ng, Carl, Su, Dian, Liu, Luna, Masih, Shabkhaiz, Sawyer, William, Tinianow, Jeff, Marik, Jan, Yip, Victor, Li, Guangmin, Chuh, Josefa, Morisaki, J. Hiroshi, Park, Summer, Zheng, Bing, Hernandez-Barry, Hilda, Loyet, Kelly M., Xu, Min, Kozak, Katherine R., Phillips, Gail Lewis, Shen, Ben-Quan, Wu, Cong, Xu, Keyang, Yu, Shang-Fan, Kamath, Amrita, Rowntree, Rebecca K., Reilly, Dorothea, Pillow, Thomas, Polson, Andrew, Schellenberger, Volker, Hazenbos, Wouter L. W., Sadowsky, Jack
Publicado 2022