Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

por Lampa, Michael, Arlt, Heike, He, Timothy, Ospina, Beatriz, Reeves, Jason, Zhang, Bailin, Murtie, Joshua, Deng, Gejing, Barberis, Claude, Hoffmann, Dietmar, Cheng, Hong, Pollard, Jack, Winter, Christopher, Richon, Victoria, Garcia-Escheverria, Carlos, Adrian, Francisco, Wiederschain, Dmitri, Srinivasan, Lakshmi
Publicado 2017

A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms

por Stefano, James E., Lord, Dana M., Zhou, Yanfeng, Jaworski, Julie, Hopke, Joern, Travaline, Tara, Zhang, Ningning, Wong, Karen, Lennon, Amanda, He, Timothy, Bric-Furlong, Eva, Cherrie, Cornishia, Magnay, Tristan, Remy, Elisabeth, Brondyk, William, Qiu, Huawei, Radošević, Katarina
Publicado 2021

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

por Griebel, Guy, Pichat, Philippe, Beeské, Sandra, Leroy, Thibaud, Redon, Nicolas, Jacquet, Agnès, Françon, Dominique, Bert, Lionel, Even, Luc, Lopez-Grancha, Mati, Tolstykh, Tatiana, Sun, Fangxian, Yu, Qunyan, Brittain, Scott, Arlt, Heike, He, Timothy, Zhang, Bailin, Wiederschain, Dmitri, Bertrand, Thomas, Houtmann, Jacques, Rak, Alexey, Vallée, François, Michot, Nadine, Augé, Franck, Menet, Véronique, Bergis, Olivier E., George, Pascal, Avenet, Patrick, Mikol, Vincent, Didier, Michel, Escoubet, Johanna
Publicado 2015