Identification of a Novel Acid Sphingomyelinase Activity Associated with Recombinant Human Acid Ceramidase

por He, Xingxuan, Schuchman, Edward H.
Publicado 2023

Ceramide and Ischemia/Reperfusion Injury

por He, Xingxuan, Schuchman, Edward H.
Publicado 2018

The Role of S1P and the Related Signaling Pathway in the Development of Tissue Fibrosis

por Wang, Erjin, He, Xingxuan, Zeng, Ming
Publicado 2019

Corrigendum: The Role of S1P and the Related Signaling Pathway in the Development of Tissue Fibrosis

por Wang, Erjin, He, Xingxuan, Zeng, Ming
Publicado 2020

Recombinant Human Acid Sphingomyelinase as an Adjuvant to Sorafenib Treatment of Experimental Liver Cancer

por Savić, Radoslav, He, Xingxuan, Fiel, Isabel, Schuchman, Edward H.
Publicado 2013

Acid Ceramidase Protects Against Hepatic Ischemia/Reperfusion Injury by Modulating Sphingolipid Metabolism and Reducing Inflammation and Oxidative Stress

por Jiang, Yuan, He, Xingxuan, Simonaro, Calogera M., Yi, Bin, Schuchman, Edward H.
Publicado 2021

Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair

por Tam, Christina, Idone, Vincent, Devlin, Cecilia, Fernandes, Maria Cecilia, Flannery, Andrew, He, Xingxuan, Schuchman, Edward, Tabas, Ira, Andrews, Norma W.
Publicado 2010

Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice

por He, Xingxuan, Dworski, Shaalee, Zhu, Changzhi, DeAngelis, Victor, Solyom, Alex, Medin, Jeffrey A., Simonaro, Calogera M., Schuchman, Edward H.
Publicado 2017

Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses

por Schuchman, Edward H., Ge, Yi, Lai, Alon, Borisov, Yury, Faillace, Meghan, Eliyahu, Efrat, He, Xingxuan, Iatridis, James, Vlassara, Helen, Striker, Gary, Simonaro, Calogera M.
Publicado 2013

Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer’s disease

por Lee, Jong Kil, Jin, Hee Kyung, Park, Min Hee, Kim, Bo-ra, Lee, Phil Hyu, Nakauchi, Hiromitsu, Carter, Janet E., He, Xingxuan, Schuchman, Edward H., Bae, Jae-sung
Publicado 2014

Acid Ceramidase Maintains the Chondrogenic Phenotype of Expanded Primary Chondrocytes and Improves the Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells

por Simonaro, Calogera M., Sachot, Sylvain, Ge, Yi, He, Xingxuan, DeAngelis, Victor A., Eliyahu, Efrat, Leong, Daniel J., Sun, Hui B., Mason, Jeffrey B., Haskins, Mark E., Richardson, Dean W., Schuchman, Edward H.
Publicado 2013

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease

por Lee, Ju Youn, Han, Seung Hoon, Park, Min Hee, Baek, Bosung, Song, Im-Sook, Choi, Min-Koo, Takuwa, Yoh, Ryu, Hoon, Kim, Seung Hyun, He, Xingxuan, Schuchman, Edward H., Bae, Jae-Sung, Jin, Hee Kyung
Publicado 2018

Pathological roles of the VEGF/SphK pathway in Niemann–Pick type C neurons

por Lee, Hyun, Lee, Jong Kil, Park, Min Hee, Hong, Yu Ri, Marti, Hugo H., Kim, Hyongbum, Okada, Yohei, Otsu, Makoto, Seo, Eul-Ju, Park, Jae-Hyung, Bae, Jae-Hoon, Okino, Nozomu, He, Xingxuan, Schuchman, Edward H., Bae, Jae-sung, Jin, Hee Kyung
Publicado 2014