Phospholipids and Alzheimer’s Disease: Alterations, Mechanisms and Potential Biomarkers

por Kosicek, Marko, Hecimovic, Silva
Publicado 2013

Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins

por Cermak, Stjepko, Kosicek, Marko, Mladenovic-Djordjevic, Aleksandra, Smiljanic, Kosara, Kanazir, Selma, Hecimovic, Silva
Publicado 2016

Cholesterol-Dependent Energy Transfer between Fluorescent Proteins—Insights into Protein Proximity of APP and BACE1 in Different Membranes in Niemann-Pick Type C Disease Cells

por von Einem, Bjoern, Weber, Petra, Wagner, Michael, Malnar, Martina, Kosicek, Marko, Hecimovic, Silva, von Arnim, Christine A. F., Schneckenburger, Herbert
Publicado 2012

Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors

por Dražić, Tonko, Sachdev, Vinay, Leopold, Christina, Patankar, Jay V., Malnar, Martina, Hećimović, Silva, Levak-Frank, Sanja, Habuš, Ivan, Kratky, Dagmar
Publicado 2015

Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors

por Dražić, Tonko, Molčanov, Krešimir, Sachdev, Vinay, Malnar, Martina, Hećimović, Silva, Patankar, Jay V., Obrowsky, Sascha, Levak-Frank, Sanja, Habuš, Ivan, Kratky, Dagmar
Publicado 2014

Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation

por Dominko, Kristina, Rastija, Ana, Sobocanec, Sandra, Vidatic, Lea, Meglaj, Sarah, Lovincic Babic, Andrea, Hutter-Paier, Birgit, Colombo, Alessio-Vittorio, Lichtenthaler, Stefan F., Tahirovic, Sabina, Hecimovic, Silva
Publicado 2021

Overlapping Neuroimmune Mechanisms and Therapeutic Targets in Neurodegenerative Disorders

por De Marchi, Fabiola, Munitic, Ivana, Vidatic, Lea, Papić, Eliša, Rački, Valentino, Nimac, Jerneja, Jurak, Igor, Novotni, Gabriela, Rogelj, Boris, Vuletic, Vladimira, Liscic, Rajka M., Cannon, Jason R., Buratti, Emanuele, Mazzini, Letizia, Hecimovic, Silva
Publicado 2023

Involvement of the Choroid Plexus in the Pathogenesis of Niemann-Pick Disease Type C

por Van Hoecke, Lien, Van Cauwenberghe, Caroline, Dominko, Kristina, Van Imschoot, Griet, Van Wonterghem, Elien, Castelein, Jonas, Xie, Junhua, Claeys, Wouter, Vandendriessche, Charysse, Kremer, Anna, Borghgraef, Peter, De Rycke, Riet, Hecimovic, Silva, Vandenbroucke, Roosmarijn E.
Publicado 2021

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

por Colombo, Alessio, Dinkel, Lina, Müller, Stephan A., Sebastian Monasor, Laura, Schifferer, Martina, Cantuti-Castelvetri, Ludovico, König, Jasmin, Vidatic, Lea, Bremova-Ertl, Tatiana, Lieberman, Andrew P., Hecimovic, Silva, Simons, Mikael, Lichtenthaler, Stefan F., Strupp, Michael, Schneider, Susanne A., Tahirovic, Sabina
Publicado 2021

BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains

por Causevic, Mirsada, Dominko, Kristina, Malnar, Martina, Vidatic, Lea, Cermak, Stjepko, Pigoni, Martina, Kuhn, Peer-Hendrik, Colombo, Alessio, Havas, Daniel, Flunkert, Stefanie, McDonald, Jessica, Gunnersen, Jenny M., Hutter-Paier, Birgit, Tahirovic, Sabina, Windisch, Manfred, Krainc, Dimitri, Lichtenthaler, Stefan F., Hecimovic, Silva
Publicado 2018

Emerging Trends in the Field of Inflammation and Proteinopathy in ALS/FTD Spectrum Disorder

por De Marchi, Fabiola, Franjkic, Toni, Schito, Paride, Russo, Tommaso, Nimac, Jerneja, Chami, Anna A., Mele, Angelica, Vidatic, Lea, Kriz, Jasna, Julien, Jean-Pierre, Apic, Gordana, Russell, Robert B., Rogelj, Boris, Cannon, Jason R., Baralle, Marco, Agosta, Federica, Hecimovic, Silva, Mazzini, Letizia, Buratti, Emanuele, Munitic, Ivana
Publicado 2023