Consistency of linkage results across exams and methods in the Framingham Heart Study

por Atwood, Larry D, Heard-Costa, Nancy L, Cupples, L Adrienne, Levy, Daniel
Publicado 2003

Sex and age specific effects of chromosomal regions linked to body mass index in the Framingham Study

por Atwood, Larry D, Heard-Costa, Nancy L, Fox, Caroline S, Jaquish, Cashell E, Cupples, L Adrienne
Publicado 2006

Trends in the Association of Parental History of Obesity over 60 Years

por Fox, Caroline S., Pencina, Michael J., Heard-Costa, Nancy L., Shrader, Peter, Jaquish, Cashell, O’Donnell, Christopher J., Vasan, Ramachandran S., Cupples, L. Adrienne, D’Agostino, Ralph B.
Publicado 2014

Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease

por Ma, Jiantao, Joehanes, Roby, Liu, Chunyu, Keshawarz, Amena, Hwang, Shih-Jen, Bui, Helena, Tejada, Brandon, Sooda, Meera, Munson, Peter J., Demirkale, Cumhur Y., Courchesne, Paul, Heard-Costa, Nancy L., Pitsillides, Achilleas N., Feolo, Mike, Sharopova, Nataliya, Vasan, Ramachandran S., Huan, Tianxiao, Levy, Daniel
Publicado 2022

Key variants via Alzheimer’s Disease Sequencing Project whole genome sequence data

por Wang, Yanbing, Sarnowski, Chloé, Lin, Honghuang, Pitsillides, Achilleas N, Heard-Costa, Nancy L, Choi, Seung Hoan, Wang, Dongyu, Bis, Joshua C, Blue, Elizabeth E, Boerwinkle, Eric, De Jager, Philip L, Fornage, Myriam, Wijsman, Ellen M, Seshadri, Sudha, Dupuis, Josée, Peloso, Gina M, DeStefano, Anita L
Publicado 2023

Whole Genome DNA and RNA Sequencing of Whole Blood Elucidates the Genetic Architecture of Gene Expression Underlying a Wide Range of Diseases

por Liu, Chunyu, Joehanes, Roby, Ma, Jiantao, Wang, Yuxuan, Sun, Xianbang, Keshawarz, Amena, Sooda, Meera, Huan, Tianxiao, Hwang, Shih-Jen, Bui, Helena, Tejada, Brandon, Munson, Peter J., Cumhur, Demirkale, Heard-Costa, Nancy L., Pitsillides, Achilleas N, Peloso, Gina M., Feolo, Michael, Sharopova, Nataliya, Vasan, Ramachandran S., Levy, Daniel
Publicado 2022

Whole Genome DNA and RNA Sequencing of Whole Blood Elucidates the Genetic Architecture of Gene Expression Underlying a Wide Range of Diseases

por Liu, Chunyu, Joehanes, Roby, Ma, Jiantao, Wang, Yuxuan, Sun, Xianbang, Keshawarz, Amena, Sooda, Meera, Huan, Tianxiao, Hwang, Shih-Jen, Bui, Helena, Tejada, Brandon, Munson, Peter J., Cumhur, Demirkale, Heard-Costa, Nancy L., Pitsillides, Achilleas N, Peloso, Gina M., Feolo, Michael, Sharopova, Nataliya, Vasan, Ramachandran S., Levy, Daniel
Publicado 2022

Whole genome DNA and RNA sequencing of whole blood elucidates the genetic architecture of gene expression underlying a wide range of diseases

por Liu, Chunyu, Joehanes, Roby, Ma, Jiantao, Wang, Yuxuan, Sun, Xianbang, Keshawarz, Amena, Sooda, Meera, Huan, Tianxiao, Hwang, Shih-Jen, Bui, Helena, Tejada, Brandon, Munson, Peter J., Demirkale, Cumhur Y., Heard-Costa, Nancy L., Pitsillides, Achilleas N., Peloso, Gina M., Feolo, Michael, Sharopova, Nataliya, Vasan, Ramachandran S., Levy, Daniel
Publicado 2022

Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer’s disease at CPT1A locus

por Sarnowski, Chloé, Huan, Tianxiao, Ma, Yiyi, Joehanes, Roby, Beiser, Alexa, DeCarli, Charles S., Heard-Costa, Nancy L., Levy, Daniel, Lin, Honghuang, Liu, Ching-Ti, Liu, Chunyu, Meigs, James B., Satizabal, Claudia L., Florez, Jose C., Hivert, Marie-France, Dupuis, Josée, De Jager, Philip L., Bennett, David A., Seshadri, Sudha, Morrison, Alanna C.
Publicado 2023

Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes

por Larson, Martin G, Atwood, Larry D, Benjamin, Emelia J, Cupples, L Adrienne, D'Agostino, Ralph B, Fox, Caroline S, Govindaraju, Diddahally R, Guo, Chao-Yu, Heard-Costa, Nancy L, Hwang, Shih-Jen, Murabito, Joanne M, Newton-Cheh, Christopher, O'Donnell, Christopher J, Seshadri, Sudha, Vasan, Ramachandran S, Wang, Thomas J, Wolf, Philip A, Levy, Daniel
Publicado 2007

Correlations between complex human phenotypes vary by genetic background, gender, and environment

por Elgart, Michael, Goodman, Matthew O., Isasi, Carmen, Chen, Han, Morrison, Alanna C., de Vries, Paul S., Xu, Huichun, Manichaikul, Ani W., Guo, Xiuqing, Franceschini, Nora, Psaty, Bruce M., Rich, Stephen S., Rotter, Jerome I., Lloyd-Jones, Donald M., Fornage, Myriam, Correa, Adolfo, Heard-Costa, Nancy L., Vasan, Ramachandran S., Hernandez, Ryan, Kaplan, Robert C., Redline, Susan, Sofer, Tamar
Publicado 2022

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population

por Kessler, Michael D., Loesch, Douglas P., Perry, James A., Heard-Costa, Nancy L., Taliun, Daniel, Cade, Brian E., Wang, Heming, Daya, Michelle, Ziniti, John, Datta, Soma, Celedón, Juan C., Soto-Quiros, Manuel E., Avila, Lydiana, Weiss, Scott T., Barnes, Kathleen, Redline, Susan S., Vasan, Ramachandran S., Johnson, Andrew D., Mathias, Rasika A., Hernandez, Ryan, Wilson, James G., Nickerson, Deborah A., Abecasis, Goncalo, Browning, Sharon R., Zöllner, Sebastian, O’Connell, Jeffrey R., Mitchell, Braxton D., O’Connor, Timothy D.
Publicado 2020

Expression quantitative trait methylation analysis elucidates gene regulatory effects of DNA methylation: the Framingham Heart Study

por Keshawarz, Amena, Bui, Helena, Joehanes, Roby, Ma, Jiantao, Liu, Chunyu, Huan, Tianxiao, Hwang, Shih-Jen, Tejada, Brandon, Sooda, Meera, Courchesne, Paul, Munson, Peter J., Demirkale, Cumhur Y., Yao, Chen, Heard-Costa, Nancy L., Pitsillides, Achilleas N., Lin, Honghuang, Liu, Ching-Ti, Wang, Yuxuan, Peloso, Gina M., Lundin, Jessica, Haessler, Jeffrey, Du, Zhaohui, Cho, Michael, Hersh, Craig P., Castaldi, Peter, Raffield, Laura M., Wen, Jia, Li, Yun, Reiner, Alexander P., Feolo, Mike, Sharopova, Nataliya, Vasan, Ramachandran S., DeMeo, Dawn L., Carson, April P., Kooperberg, Charles, Levy, Daniel
Publicado 2023

Association of Common and Rare Variants with Alzheimer’s Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer’s Disease Sequencing Project

por Lee, Wan-Ping, Choi, Seung Hoan, Shea, Margaret G, Cheng, Po-Liang, Dombroski, Beth A, Pitsillides, Achilleas N, Heard-Costa, Nancy L, Wang, Hui, Bulekova, Katia, Kuzma, Amanda B, Leung, Yuk Yee, Farrell, John J, Lin, Honghuang, Naj, Adam, Blue, Elizabeth E, Nusetor, Frederick, Wang, Dongyu, Boerwinkle, Eric, Bush, William S, Zhang, Xiaoling, De Jager, Philip L, Dupuis, Josée, Farrer, Lindsay A, Fornage, Myriam, Martin, Eden, Pericak-Vance, Margaret, Seshadri, Sudha, Wijsman, Ellen M, Wang, Li-San, Schellenberg, Gerard D, Destefano, Anita L, Haines, Jonathan L, Peloso, Gina M
Publicado 2023

The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports

por Cupples, L Adrienne, Arruda, Heather T, Benjamin, Emelia J, D'Agostino, Ralph B, Demissie, Serkalem, DeStefano, Anita L, Dupuis, Josée, Falls, Kathleen M, Fox, Caroline S, Gottlieb, Daniel J, Govindaraju, Diddahally R, Guo, Chao-Yu, Heard-Costa, Nancy L, Hwang, Shih-Jen, Kathiresan, Sekar, Kiel, Douglas P, Laramie, Jason M, Larson, Martin G, Levy, Daniel, Liu, Chun-Yu, Lunetta, Kathryn L, Mailman, Matthew D, Manning, Alisa K, Meigs, James B, Murabito, Joanne M, Newton-Cheh, Christopher, O'Connor, George T, O'Donnell, Christopher J, Pandey, Mona, Seshadri, Sudha, Vasan, Ramachandran S, Wang, Zhen Y, Wilk, Jemma B, Wolf, Philip A, Yang, Qiong, Atwood, Larry D
Publicado 2007

Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment

por Nagtegaal, Andries Paul, Broer, Linda, Zilhao, Nuno R., Jakobsdottir, Johanna, Bishop, Charles E., Brumat, Marco, Christiansen, Mark W., Cocca, Massimiliano, Gao, Yan, Heard-Costa, Nancy L., Evans, Daniel S., Pankratz, Nathan, Pratt, Sheila R., Price, T. Ryan, Spankovich, Christopher, Stimson, Mary R., Valle, Karen, Vuckovic, Dragana, Wells, Helena, Eiriksdottir, Gudny, Fransen, Erik, Ikram, Mohammad Arfan, Li, Chuang-Ming, Longstreth, W. T., Steves, Claire, Van Camp, Guy, Correa, Adolfo, Cruickshanks, Karen J., Gasparini, Paolo, Girotto, Giorgia, Kaplan, Robert C., Nalls, Michael, Schweinfurth, John M., Seshadri, Sudha, Sotoodehnia, Nona, Tranah, Gregory J., Uitterlinden, André G., Wilson, James G., Gudnason, Vilmundur, Hoffman, Howard J., Williams, Frances M. K., Goedegebure, André
Publicado 2019

NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium

por Heard-Costa, Nancy L., Zillikens, M. Carola, Monda, Keri L., Johansson, Åsa, Harris, Tamara B., Fu, Mao, Haritunians, Talin, Feitosa, Mary F., Aspelund, Thor, Eiriksdottir, Gudny, Garcia, Melissa, Launer, Lenore J., Smith, Albert V., Mitchell, Braxton D., McArdle, Patrick F., Shuldiner, Alan R., Bielinski, Suzette J., Boerwinkle, Eric, Brancati, Fred, Demerath, Ellen W., Pankow, James S., Arnold, Alice M., Chen, Yii-Der Ida, Glazer, Nicole L., McKnight, Barbara, Psaty, Bruce M., Rotter, Jerome I., Amin, Najaf, Campbell, Harry, Gyllensten, Ulf, Pattaro, Cristian, Pramstaller, Peter P., Rudan, Igor, Struchalin, Maksim, Vitart, Veronique, Gao, Xiaoyi, Kraja, Aldi, Province, Michael A., Zhang, Qunyuan, Atwood, Larry D., Dupuis, Josée, Hirschhorn, Joel N., Jaquish, Cashell E., O'Donnell, Christopher J., Vasan, Ramachandran S., White, Charles C., Aulchenko, Yurii S., Estrada, Karol, Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., Witteman, Jacqueline C. M., Oostra, Ben A., Kaplan, Robert C., Gudnason, Vilmundur, O'Connell, Jeffrey R., Borecki, Ingrid B., van Duijn, Cornelia M., Cupples, L. Adrienne, Fox, Caroline S., North, Kari E.
Publicado 2009

Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss

por Trpchevska, Natalia, Freidin, Maxim B., Broer, Linda, Oosterloo, Berthe C., Yao, Shuyang, Zhou, Yitian, Vona, Barbara, Bishop, Charles, Bizaki-Vallaskangas, Argyro, Canlon, Barbara, Castellana, Fabio, Chasman, Daniel I., Cherny, Stacey, Christensen, Kaare, Concas, Maria Pina, Correa, Adolfo, Elkon, Ran, Mengel-From, Jonas, Gao, Yan, Giersch, Anne B.S., Girotto, Giorgia, Gudjonsson, Alexander, Gudnason, Vilmundur, Heard-Costa, Nancy L., Hertzano, Ronna, Hjelmborg, Jacob v.B., Hjerling-Leffler, Jens, Hoffman, Howard J., Kaprio, Jaakko, Kettunen, Johannes, Krebs, Kristi, Kähler, Anna K., Lallemend, Francois, Launer, Lenore J., Lee, I-Min, Leonard, Hampton, Li, Chuan-Ming, Lowenheim, Hubert, Magnusson, Patrik K.E., van Meurs, Joyce, Milani, Lili, Morton, Cynthia C., Mäkitie, Antti, Nalls, Mike A., Nardone, Giuseppe Giovanni, Nygaard, Marianne, Palviainen, Teemu, Pratt, Sheila, Quaranta, Nicola, Rämö, Joel, Saarentaus, Elmo, Sardone, Rodolfo, Satizabal, Claudia L., Schweinfurth, John M., Seshadri, Sudha, Shiroma, Eric, Shulman, Eldad, Simonsick, Eleanor, Spankovich, Christopher, Tropitzsch, Anke, Lauschke, Volker M., Sullivan, Patrick F., Goedegebure, Andre, Cederroth, Christopher R., Williams, Frances M.K., Nagtegaal, Andries Paul
Publicado 2022

Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants

por Young, Kristin L., Fisher, Virginia, Deng, Xuan, Brody, Jennifer A., Graff, Misa, Lim, Elise, Lin, Bridget M., Xu, Hanfei, Amin, Najaf, An, Ping, Aslibekyan, Stella, Fohner, Alison E., Hidalgo, Bertha, Lenzini, Petra, Kraaij, Robert, Medina-Gomez, Carolina, Prokić, Ivana, Rivadeneira, Fernando, Sitlani, Colleen, Tao, Ran, van Rooij, Jeroen, Zhang, Di, Broome, Jai G., Buth, Erin J., Heavner, Benjamin D., Jain, Deepti, Smith, Albert V., Barnes, Kathleen, Boorgula, Meher Preethi, Chavan, Sameer, Darbar, Dawood, De Andrade, Mariza, Guo, Xiuqing, Haessler, Jeffrey, Irvin, Marguerite R., Kalyani, Rita R., Kardia, Sharon L.R., Kooperberg, Charles, Kim, Wonji, Mathias, Rasika A., McDonald, Merry-Lynn, Mitchell, Braxton D., Peyser, Patricia A., Regan, Elizabeth A., Redline, Susan, Reiner, Alexander P., Rich, Stephen S., Rotter, Jerome I., Smith, Jennifer A., Weiss, Scott, Wiggins, Kerri L., Yanek, Lisa R., Arnett, Donna, Heard-Costa, Nancy L., Leal, Suzanne, Lin, Danyu, McKnight, Barbara, Province, Michael, van Duijn, Cornelia M., North, Kari E., Cupples, L. Adrienne, Liu, Ching-Ti
Publicado 2022

A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies

por Li, Xihao, Chen, Han, Selvaraj, Margaret Sunitha, Van Buren, Eric, Zhou, Hufeng, Wang, Yuxuan, Sun, Ryan, McCaw, Zachary R., Yu, Zhi, Arnett, Donna K., Bis, Joshua C., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Brody, Jennifer A., Cade, Brian E., Carson, April P., Carlson, Jenna C., Chami, Nathalie, Chen, Yii-Der Ida, Curran, Joanne E., de Vries, Paul S., Fornage, Myriam, Franceschini, Nora, Freedman, Barry I., Gu, Charles, Heard-Costa, Nancy L., He, Jiang, Hou, Lifang, Hung, Yi-Jen, Irvin, Marguerite R., Kaplan, Robert C., Kardia, Sharon L.R., Kelly, Tanika, Konigsberg, Iain, Kooperberg, Charles, Kral, Brian G., Li, Changwei, Loos, Ruth J.F., Mahaney, Michael C., Martin, Lisa W., Mathias, Rasika A., Minster, Ryan L., Mitchell, Braxton D., Montasser, May E., Morrison, Alanna C., Palmer, Nicholette D., Peyser, Patricia A., Psaty, Bruce M., Raffield, Laura M., Redline, Susan, Reiner, Alexander P., Rich, Stephen S., Sitlani, Colleen M., Smith, Jennifer A., Taylor, Kent D., Tiwari, Hemant, Vasan, Ramachandran S., Wang, Zhe, Yanek, Lisa R., Yu, Bing, Rice, Kenneth M., Rotter, Jerome I., Peloso, Gina M., Natarajan, Pradeep, Li, Zilin, Liu, Zhonghua, Lin, Xihong
Publicado 2023