Isolation of blood-brain barrier-crossing antibodies from a phage display library by competitive elution and their ability to penetrate the central nervous system

por Thom, George, Hatcher, Jon, Hearn, Arron, Paterson, Judy, Rodrigo, Natalia, Beljean, Arthur, Gurrell, Ian, Webster, Carl
Publicado 2017

A deimmunised form of the ribotoxin, α-sarcin, lacking CD4(+) T cell epitopes and its use as an immunotoxin warhead

por Jones, Tim D., Hearn, Arron R., Holgate, Robert G.E., Kozub, Dorota, Fogg, Mark H., Carr, Francis J., Baker, Matthew P., Lacadena, Javier, Gehlsen, Kurt R.
Publicado 2016

Selective blood-brain barrier permeabilization of brain metastases by a type 1 receptor-selective tumor necrosis factor mutein

por Munoz Pinto, Mario F, Campbell, Sandra J, Simoglou Karali, Christina, Johanssen, Vanessa A, Bristow, Claire, Cheng, Vinton W T, Zarghami, Niloufar, Larkin, James R, Pannell, Maria, Hearn, Arron, Chui, Cherry, Brinquis Nunez, Barbara, Bokma, Evert, Holgate, Robert, Anthony, Daniel C, Sibson, Nicola R
Publicado 2021