The challenges, advantages and future of phenome-wide association studies

por Hebbring, Scott J
Publicado 2014

Utilizing Genotype Imputation for the Augmentation of Sequence Data

por Fridley, Brooke L., Jenkins, Gregory, Deyo-Svendsen, Matthew E., Hebbring, Scott, Freimuth, Robert
Publicado 2010

Estimating the efficacy of pharmacogenomics over a lifetime

por Ye, Zhan, Mayer, John, Leary, Emili J., Kitchner, Terrie, Dart, Richard A., Brilliant, Murray H., Hebbring, Scott J.
Publicado 2023

Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach

por Kalari, Krishna R, Hebbring, Scott J, Chai, High Seng, Li, Liang, Kocher, Jean-Pierre A, Wang, Liewei, Weinshilboum, Richard M
Publicado 2010

Kidney failure in Bardet–Biedl syndrome

por Meyer, Jennifer R., Krentz, Anthony D., Berg, Richard L., Richardson, Jesse G., Pomeroy, Jeremy, Hebbring, Scott J., Haws, Robert M.
Publicado 2022

The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem

por Maadooliat, Mehdi, Bansal, Naveen K., Upadhya, Jiblal, Farazi, Manzur R., Li, Xiang, He, Max M., Hebbring, Scott J., Ye, Zhan, Schrodi, Steven J.
Publicado 2016

Genetic and clinical determinants of telomere length

por Allaire, Patrick, He, Jing, Mayer, John, Moat, Luke, Gerstenberger, Peter, Wilhorn, Reynor, Strutz, Sierra, Kim, David S.L., Zeng, Chenjie, Cox, Nancy, Shay, Jerry W., Denny, Joshua, Bastarache, Lisa, Hebbring, Scott
Publicado 2023

An independently validated, portable algorithm for the rapid identification of COPD patients using electronic health records

por Chu, Su H., Wan, Emily S., Cho, Michael H., Goryachev, Sergey, Gainer, Vivian, Linneman, James, Scotty, Erica J., Hebbring, Scott J., Murphy, Shawn, Lasky-Su, Jessica, Weiss, Scott T., Smoller, Jordan W., Karlson, Elizabeth
Publicado 2021

Identifying genetically driven clinical phenotypes using linear mixed models

por Mosley, Jonathan D., Witte, John S., Larkin, Emma K., Bastarache, Lisa, Shaffer, Christian M., Karnes, Jason H., Stein, C. Michael, Phillips, Elizabeth, Hebbring, Scott J., Brilliant, Murray H., Mayer, John, Ye, Zhan, Roden, Dan M., Denny, Joshua C.
Publicado 2016

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics

por Ji, Yuan, Biernacka, Joanna M., Hebbring, Scott, Chai, Yubo, Jenkins, Gregory D., Batzler, Anthony, Snyder, Karen A., Drews, Maureen S., Desta, Zeruesenay, Flockhart, David, Mushiroda, Taisei, Kubo, Michiaki, Nakamura, Yusuke, Kamatani, Naoyuki, Schaid, Daniel, Weinshilboum, Richard M., Mrazek, David A.
Publicado 2012

SeqHBase: a big data toolset for family based sequencing data analysis

por He, Min, Person, Thomas N, Hebbring, Scott J, Heinzen, Ethan, Ye, Zhan, Schrodi, Steven J, McPherson, Elizabeth W, Lin, Simon M, Peissig, Peggy L, Brilliant, Murray H, O'Rawe, Jason, Robison, Reid J, Lyon, Gholson J, Wang, Kai
Publicado 2015

Mining Retrospective Data for Virtual Prospective Drug Repurposing: L-DOPA and Age-related Macular Degeneration

por Brilliant, Murray H., Vaziri, Kamyar, Connor, Thomas B., Schwartz, Stephen G., Carroll, Joseph J., McCarty, Catherine A., Schrodi, Steven J., Hebbring, Scott J., Kishor, Krishna S., Flynn, Harry W., Moshfeghi, Andrew A., Moshfeghi, Darius M., Fini, M. Elizabeth, McKay, Brian S.
Publicado 2015

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

por Verma, Anurag, Verma, Shefali S., Pendergrass, Sarah A., Crawford, Dana C., Crosslin, David R., Kuivaniemi, Helena, Bush, William S., Bradford, Yuki, Kullo, Iftikhar, Bielinski, Suzette J., Li, Rongling, Denny, Joshua C., Peissig, Peggy, Hebbring, Scott, De Andrade, Mariza, Ritchie, Marylyn D., Tromp, Gerard
Publicado 2016

The genetic architecture of plasma kynurenine includes cardiometabolic disease mechanisms associated with the SH2B3 gene

por Bagheri, Minoo, Wang, Chuan, Shi, Mingjian, Manouchehri, Ali, Murray, Katherine T., Murphy, Matthew B., Shaffer, Christian M., Singh, Kritika, Davis, Lea K., Jarvik, Gail P., Stanaway, Ian B., Hebbring, Scott, Reilly, Muredach P., Gerszten, Robert E., Wang, Thomas J., Mosley, Jonathan D., Ferguson, Jane F.
Publicado 2021

Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders

por Zhang, Xinyuan, Lucas, Anastasia M., Veturi, Yogasudha, Drivas, Theodore G., Bone, William P., Verma, Anurag, Chung, Wendy K., Crosslin, David, Denny, Joshua C., Hebbring, Scott, Jarvik, Gail P., Kullo, Iftikhar, Larson, Eric B., Rasmussen-Torvik, Laura J., Schaid, Daniel J., Smoller, Jordan W., Stanaway, Ian B., Wei, Wei-Qi, Weng, Chunhua, Ritchie, Marylyn D.
Publicado 2022

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

por Zhang, Xinyuan, Veturi, Yogasudha, Verma, Shefali, Bone, William, Verma, Anurag, Lucas, Anastasia, Hebbring, Scott, Denny, Joshua C., Stanaway, Ian B., Jarvik, Gail P., Crosslin, David, Larson, Eric B., Rasmussen-Torvik, Laura, Pendergrass, Sarah A., Smoller, Jordan W., Hakonarson, Hakon, Sleiman, Patrick, Weng, Chunhua, Fasel, David, Wei, Wei-Qi, Kullo, Iftikhar, Schaid, Daniel, Chung, Wendy K., Ritchie, Marylyn D.
Publicado 2019

Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy

por Van Driest, Sara L., McGregor, Tracy L., Velez Edwards, Digna R., Saville, Ben R., Kitchner, Terrie E., Hebbring, Scott J., Brilliant, Murray, Jouni, Hayan, Kullo, Iftikhar J., Creech, C. Buddy, Kannankeril, Prince J., Vear, Susan I., Brothers, Kyle B., Bowton, Erica A., Shaffer, Christian M., Patel, Neelam, Delaney, Jessica T., Bradford, Yuki, Wilson, Sarah, Olson, Lana M., Crawford, Dana C., Potts, Amy L., Ho, Richard H., Roden, Dan M., Denny, Josh C.
Publicado 2015

Penetrance of Breast Cancer Susceptibility Genes From the eMERGE III Network

por Fan, Xiao, Wynn, Julia, Shang, Ning, Liu, Cong, Fedotov, Alexander, Hallquist, Miranda L G, Buchanan, Adam H, Williams, Marc S, Smith, Maureen E, Hoell, Christin, Rasmussen-Torvik, Laura J, Peterson, Josh F, Wiesner, Georgia L, Murad, Andrea M, Jarvik, Gail P, Gordon, Adam S, Rosenthal, Elisabeth A, Stanaway, Ian B, Crosslin, David R, Larson, Eric B, Leppig, Kathleen A, Henrikson, Nora B, Williams, Janet L, Li, Rongling, Hebbring, Scott, Weng, Chunhua, Shen, Yufeng, Crew, Katherine D, Chung, Wendy K
Publicado 2021

Understanding the Return of Genomic Sequencing Results Process: Content Review of Participant Summary Letters in the eMERGE Research Network

por Lynch, John A., Sharp, Richard R., Aufox, Sharon A., Bland, Sarah T., Blout, Carrie, Bowen, Deborah J., Buchanan, Adam H., Halverson, Colin, Harr, Margaret, Hebbring, Scott J., Henrikson, Nora, Hoell, Christin, Holm, Ingrid A., Jarvik, Gail, Kullo, Iftikhar J., Kochan, David C., Larson, Eric B., Lazzeri, Amanda, Leppig, Kathleen A., Madden, Jill, Marasa, Maddalena, Myers, Melanie F., Peterson, Josh, Prows, Cynthia A., Kulchak Rahm, Alanna, Ralston, James, Milo Rasouly, Hila, Scrol, Aaron, Smith, Maureen E., Sturm, Amy, Stuttgen, Kelsey, Wiesner, Georgia, Williams, Marc S., Wynn, Julia, Williams, Janet L.
Publicado 2020

A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR

por Safarova, Maya S., Satterfield, Benjamin A., Fan, Xiao, Austin, Erin E., Ye, Zhan, Bastarache, Lisa, Zheng, Neil, Ritchie, Marylyn D., Borthwick, Kenneth M., Williams, Marc S., Larson, Eric B., Scrol, Aaron, Jarvik, Gail P., Crosslin, David R., Leppig, Kathleen, Rasmussen-Torvik, Laura J., Pendergrass, Sarah A., Sturm, Amy C., Namjou, Bahram, Shah, Amy Sanghavi, Carroll, Robert J., Chung, Wendy K., Wei, Wei-Qi, Feng, QiPing, Stein, C. Michael, Roden, Dan M., Manolio, Teri A., Schaid, Daniel J., Denny, Joshua C., Hebbring, Scott J., de Andrade, Mariza, Kullo, Iftikhar J.
Publicado 2019