NTRK insights: best practices for pathologists

por Hechtman, Jaclyn F.
Publicado 2021

Loss of Central Inhibition: Implications for Behavioral Hypersensitivity after Contusive Spinal Cord Injury in Rats

por Berrocal, Yerko A., Almeida, Vania W., Puentes, Rocio, Knott, Eric P., Hechtman, Jaclyn F., Garland, Mary, Pearse, Damien D.
Publicado 2014

DNAJB1-PRKACA fusions occur in oncocytic pancreatic and biliary neoplasms and are not specific for fibrolamellar hepatocellular carcinoma

por Vyas, Monika, Hechtman, Jaclyn F., Zhang, Yanming, Benayed, Ryma, Yavas, Aslihan, Askan, Gokce, Shia, Jinru, Klimstra, David S., Basturk, Olca
Publicado 2019

Subclinical focal Cholangitis mimicking liver metastasis in asymptomatic patients with history of pancreatic Ductal Adenocarcinoma and Biliary tree intervention

por Horvat, Natally, Godfrey, Edmund M., Sadler, Timothy J., Hechtman, Jaclyn F., Tang, Laura H., Sigel, Carlie S., Monti, Serena, Mannelli, Lorenzo
Publicado 2017

Retained Mismatch Repair Protein Expression Occurs in Approximately 6% of Microsatellite Instability-High Cancers and is Associated with Missense Mutations in Mismatch Repair Genes...

por Hechtman, Jaclyn F., Rana, Satshil, Middha, Sumit, Stadler, Zsofia K., Latham, Alicia, Benayed, Ryma, Soslow, Robert, Ladanyi, Marc, Yaeger, Rona, Zehir, Ahmet, Shia, Jinru
Publicado 2019

Larotrectinib Demonstrates CNS Efficacy in TRK Fusion-Positive Solid Tumors

por Rosen, Ezra Y., Schram, Alison M., Young, Robert J., Schreyer, Mark W., Hechtman, Jaclyn F., Shu, Catherine A., Ku, Nora C., Hyman, David M., Drilon, Alexander
Publicado 2019

Carcinomas assemble a filamentous CXCL12–keratin-19 coating that suppresses T cell–mediated immune attack

por Wang, Zhikai, Moresco, Philip, Yan, Ran, Li, Jiayun, Gao, Ya, Biasci, Daniele, Yao, Min, Pearson, Jordan, Hechtman, Jaclyn F., Janowitz, Tobias, Zaidi, Raza M., Weiss, Matthew J., Fearon, Douglas T.
Publicado 2022

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma

por Javier, Breanna M., Yaeger, Rona, Wang, Lu, Sanchez-Vega, Francisco, Zehir, Ahmet, Middha, Sumit, Sadowska, Justyna, Vakiani, Efsevia, Shia, Jinru, Klimstra, David, Ladanyi, Marc, Iacobuzio-Donahue, Christine A., Hechtman, Jaclyn F.
Publicado 2016

Genomic stratification beyond Ras/B‐Raf in colorectal liver metastasis patients treated with hepatic arterial infusion

por Smith, J. Joshua, Chatila, Walid K., Sanchez‐Vega, Francisco, Datta, Jashodeep, Connell, Louise C., Szeglin, Bryan C., Basunia, Azfar, Boucher, Taryn M., Hauser, Haley, Wasserman, Isaac, Wu, Chao, Cercek, Andrea, Hechtman, Jaclyn F., Madden, Chris, Jarnagin, William R., Garcia‐Aguilar, Julio, D'Angelica, Michael I., Yaeger, Rona, Schultz, Nikolaus, Kemeny, Nancy E.
Publicado 2019

Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology

por Tao, Jessica J., Eubank, Michael H., Schram, Alison M., Cangemi, Nicholas, Pamer, Erika, Rosen, Ezra Y., Schultz, Nikolaus, Chakravarty, Debyani, Philip, John, Hechtman, Jaclyn F., Harding, James J., Smyth, Lillian M., Jhaveri, Komal L., Drilon, Alexander, Ladanyi, Marc, Solit, David B., Zehir, Ahmet, Berger, Michael F., Stetson, Peter D., Gardos, Stuart M., Hyman, David M.
Publicado 2019

MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation

por Schaefer, Inga-Marie, Wang, Yuexiang, Liang, Cher-wei, Bahri, Nacef, Quattrone, Anna, Doyle, Leona, Mariño-Enríquez, Adrian, Lauria, Alexandra, Zhu, Meijun, Debiec-Rychter, Maria, Grunewald, Susanne, Hechtman, Jaclyn F., Dufresne, Armelle, Antonescu, Cristina R., Beadling, Carol, Sicinska, Ewa T., van de Rijn, Matt, Demetri, George D., Ladanyi, Marc, Corless, Christopher L., Heinrich, Michael C., Raut, Chandrajit P., Bauer, Sebastian, Fletcher, Jonathan A.
Publicado 2017

Prevalence of Germline Alterations on Targeted Tumor-Normal Sequencing of Esophagogastric Cancer

por Ku, Geoffrey Y., Kemel, Yelena, Maron, Steve B., Chou, Joanne F., Ravichandran, Vignesh, Shameer, Zarina, Maio, Anna, Won, Elizabeth S., Kelsen, David P., Ilson, David H., Capanu, Marinela, Strong, Vivian E., Molena, Daniela, Sihag, Smita, Jones, David R., Coit, Daniel G., Tuvy, Yaelle, Cowie, Kendall, Solit, David B., Schultz, Nikolaus, Hechtman, Jaclyn F., Offit, Kenneth, Joseph, Vijai, Mandelker, Diana, Janjigian, Yelena Y., Stadler, Zsofia K.
Publicado 2021

Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation

por Cocco, Emiliano, Schram, Alison M, Kulick, Amanda, Misale, Sandra, Won, Helen H, Yaeger, Rona, Razavi, Pedram, Ptashkin, Ryan, Hechtman, Jaclyn F, Toska, Eneda, Cownie, James, Somwar, Romel, Shifman, Sophie, Mattar, Marissa, Selçuklu, S Duygu, Samoila, Aliaksandra, Guzman, Sean, Tuch, Brian B, Ebata, Kevin, de Stanchina, Elisa, Nagy, Rebecca J, Lanman, Richard B, Houck-Loomis, Brian, Patel, Juber A, Berger, Michael F, Ladanyi, Marc, Hyman, David M, Drilon, Alexander, Scaltriti, Maurizio
Publicado 2019

Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers

por Chatila, Walid K., Walch, Henry, Hechtman, Jaclyn F., Moyer, Sydney M., Sgambati, Valeria, Faleck, David M., Srivastava, Amitabh, Tang, Laura, Benhamida, Jamal, Ismailgeci, Dorina, Campos, Carl, Wu, Fan, Chang, Qing, Vakiani, Efsevia, de Stanchina, Elisa, Weiser, Martin R., Widmar, Maria, Yantiss, Rhonda K., Shah, Manish A., Bass, Adam J., Stadler, Zsofia K., Katz, Lior H., Mellinghoff, Ingo K., Sethi, Nilay S., Schultz, Nikolaus, Ganesh, Karuna, Kelsen, David, Yaeger, Rona
Publicado 2023

Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer

por Maron, Steven B., Chatila, Walid, Walch, Henry, Chou, Joanne F., Ceglia, Nicholas, Ptashkin, Ryan, Do, Richard Kinh Gian, Paroder, Viktoriya, Pandit-Taskar, Neeta, Lewis, Jason S., Biachi De Castria, Tiago, Sabwa, Shalom, Socolow, Fiona, Feder, Lara, Thomas, Jasmine, Schulze, Isabell, Kim, Kwanghee, Elzein, Arijh, Bojilova, Viktoria, Zatzman, Matthew, Bhanot, Umesh, Nagy, Rebecca J., Lee, Jeeyun, Simmons, Marc, Segal, Michal, Ku, Geoffrey Yuyat, Ilson, David H., Capanu, Marinela, Hechtman, Jaclyn F., Merghoub, Taha, Shah, Sohrab, Schultz, Nikolaus, Solit, David B., Janjigian, Yelena Y.
Publicado 2023

ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper

por Dasari, Arvind, Morris, Van K., Allegra, Carmen J., Atreya, Chloe, Benson, Al B., Boland, Patrick, Chung, Ki, Copur, Mehmet S., Corcoran, Ryan B., Deming, Dustin A., Dwyer, Andrea, Diehn, Maximilian, Eng, Cathy, George, Thomas J., Gollub, Marc J., Goodwin, Rachel A., Hamilton, Stanley R., Hechtman, Jaclyn F., Hochster, Howard, Hong, Theodore S., Innocenti, Federico, Iqbal, Atif, Jacobs, Samuel A., Kennecke, Hagen F., Lee, James J., Lieu, Christopher H., Lenz, Heinz-Josef, Lindwasser, O. Wolf, Montagut, Clara, Odisio, Bruno, Ou, Fang-Shu, Porter, Laura, Raghav, Kanwal, Schrag, Deborah, Scott, Aaron J., Shi, Qian, Strickler, John H., Venook, Alan, Yaeger, Rona, Yothers, Greg, You, Y. Nancy, Zell, Jason A., Kopetz, Scott
Publicado 2020

Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS

por Rose Brannon, A., Jayakumaran, Gowtham, Diosdado, Monica, Patel, Juber, Razumova, Anna, Hu, Yu, Meng, Fanli, Haque, Mohammad, Sadowska, Justyna, Murphy, Brian J., Baldi, Tessara, Johnson, Ian, Ptashkin, Ryan, Hasan, Maysun, Srinivasan, Preethi, Rema, Anoop Balakrishnan, Rijo, Ivelise, Agarunov, Aaron, Won, Helen, Perera, Dilmi, Brown, David N., Samoila, Aliaksandra, Jing, Xiaohong, Gedvilaite, Erika, Yang, Julie L., Stephens, Dennis P., Dix, Jenna-Marie, DeGroat, Nicole, Nafa, Khedoudja, Syed, Aijazuddin, Li, Alan, Lebow, Emily S., Bowman, Anita S., Ferguson, Donna C., Liu, Ying, Mata, Douglas A., Sharma, Rohit, Yang, Soo-Ryum, Bale, Tejus, Benhamida, Jamal K., Chang, Jason C., Dogan, Snjezana, Hameed, Meera R., Hechtman, Jaclyn F., Moung, Christine, Ross, Dara S., Vakiani, Efsevia, Vanderbilt, Chad M., Yao, JinJuan, Razavi, Pedram, Smyth, Lillian M., Chandarlapaty, Sarat, Iyer, Gopa, Abida, Wassim, Harding, James J., Krantz, Benjamin, O’Reilly, Eileen, Yu, Helena A., Li, Bob T., Rudin, Charles M., Diaz, Luis, Solit, David B., Arcila, Maria E., Ladanyi, Marc, Loomis, Brian, Tsui, Dana, Berger, Michael F., Zehir, Ahmet, Benayed, Ryma
Publicado 2021

Mutational Landscape of Metastatic Cancer Revealed from Prospective Clinical Sequencing of 10,000 Patients

por Zehir, Ahmet, Benayed, Ryma, Shah, Ronak H., Syed, Aijazuddin, Middha, Sumit, Kim, Hyunjae R., Srinivasan, Preethi, Gao, Jianjiong, Chakravarty, Debyani, Devlin, Sean M., Hellmann, Matthew D., Barron, David A., Schram, Alison M., Hameed, Meera, Dogan, Snjezana, Ross, Dara S., Hechtman, Jaclyn F., DeLair, Deborah F., Yao, JinJuan, Mandelker, Diana L., Cheng, Donavan T., Chandramohan, Raghu, Mohanty, Abhinita S., Ptashkin, Ryan N., Jayakumaran, Gowtham, Prasad, Meera, Syed, Mustafa H., Rema, Anoop Balakrishnan, Liu, Zhen Y., Nafa, Khedoudja, Borsu, Laetitia, Sadowska, Justyna, Casanova, Jacklyn, Bacares, Ruben, Kiecka, Iwona J., Razumova, Anna, Son, Julie B., Stewart, Lisa, Baldi, Tessara, Mullaney, Kerry A., Al-Ahmadie, Hikmat, Vakiani, Efsevia, Abeshouse, Adam A., Penson, Alexander V., Jonsson, Philip, Camacho, Niedzica, Chang, Matthew T., Won, Helen H., Gross, Benjamin E., Kundra, Ritika, Heins, Zachary J., Chen, Hsiao-Wei, Phillips, Sarah, Zhang, Hongxin, Wang, Jiaojiao, Ochoa, Angelica, Wills, Jonathan, Eubank, Michael, Thomas, Stacy B., Gardos, Stuart M., Reales, Dalicia N., Galle, Jesse, Durany, Robert, Cambria, Roy, Abida, Wassim, Cercek, Andrea, Feldman, Darren R., Gounder, Mrinal M., Hakimi, A. Ari, Harding, James J., Iyer, Gopa, Janjigian, Yelena Y., Jordan, Emmet J., Kelly, Ciara M., Lowery, Maeve A., Morris, Luc G.T., Omuro, Antonio M., Raj, Nitya, Razavi, Pedram, Shoushtari, Alexander N., Shukla, Neerav, Soumerai, Tara E., Varghese, Anna M., Yaeger, Rona, Coleman, Jonathan, Bochner, Bernard, Riely, Gregory J., Saltz, Leonard B., Scher, Howard I., Sabbatini, Paul J., Robson, Mark E., Klimstra, David S., Taylor, Barry S., Baselga, Jose, Schultz, Nikolaus, Hyman, David M., Arcila, Maria E., Solit, David B., Ladanyi, Marc, Berger, Michael F.
Publicado 2017