Comparison of Structural and Short Variants Detected by Linked-Read and Whole-Exome Sequencing in Multiple Myeloma

por Kumar, Ashwini, Adhikari, Sadiksha, Kankainen, Matti, Heckman, Caroline A.
Publicado 2021

The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia

por Kumar, Ashwini, Kankainen, Matti, Parsons, Alun, Kallioniemi, Olli, Mattila, Pirkko, Heckman, Caroline A.
Publicado 2017

Combined gene essentiality scoring improves the prediction of cancer dependency maps

por Wang, Wenyu, Malyutina, Alina, Pessia, Alberto, Saarela, Jani, Heckman, Caroline A., Tang, Jing
Publicado 2019

Corrigendum to ‘Combined gene essentiality scoring improves the prediction of cancer dependency maps’ [EBioMedicine 50 (2019) 66–79]

por Wang, Wenyu, Malyutina, Alina, Pessia, Alberto, Saarela, Jani, Heckman, Caroline A., Tang, Jing
Publicado 2020

Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer

por Malyutina, Alina, Majumder, Muntasir Mamun, Wang, Wenyu, Pessia, Alberto, Heckman, Caroline A., Tang, Jing
Publicado 2019

An ischemic myelopathy case series: Flaccid paraplegia following a spike ball save and numbness while walking normally

por Heckman, Caroline A., Miller, Derryl J., Kremer, Kelly M., Martinez, Mesha L., Jea, Andrew H.
Publicado 2023

Using Proteomics Data to Identify Personalized Treatments in Multiple Myeloma: A Machine Learning Approach

por Katsenou, Angeliki, O’Farrell, Roisin, Dowling, Paul, Heckman, Caroline A., O’Gorman, Peter, Bazou, Despina
Publicado 2023

FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML

por Kivioja, Jarno, Malani, Disha, Kumar, Ashwini, Kontro, Mika, Parsons, Alun, Kallioniemi, Olli, Heckman, Caroline A.
Publicado 2021

MCL-1 inhibitors, fast-lane development of a new class of anti-cancer agents

por Bolomsky, Arnold, Vogler, Meike, Köse, Murat Cem, Heckman, Caroline A., Ehx, Grégory, Ludwig, Heinz, Caers, Jo
Publicado 2020

Correction to: MCL-1 inhibitors, fast-lane development of a new class of anti-cancer agents

por Bolomsky, Arnold, Vogler, Meike, Köse, Murat Cem, Heckman, Caroline A., Ehx, Grégory, Ludwig, Heinz, Caers, Jo
Publicado 2021

Identification of Protein Biomarker Signatures for Acute Myeloid Leukemia (AML) Using Both Nontargeted and Targeted Approaches

por Dowling, Paul, Tierney, Ciara, Dunphy, Katie, Miettinen, Juho J., Heckman, Caroline A., Bazou, Despina, O’Gorman, Peter
Publicado 2021

Bipartite network models to design combination therapies in acute myeloid leukaemia

por Jafari, Mohieddin, Mirzaie, Mehdi, Bao, Jie, Barneh, Farnaz, Zheng, Shuyu, Eriksson, Johanna, Heckman, Caroline A., Tang, Jing
Publicado 2022

An immunity and pyroptosis gene-pair signature predicts overall survival in acute myeloid leukemia

por Kong, Weikaixin, He, Liye, Zhu, Jie, Brück, Oscar, Porkka, Kimmo, Heckman, Caroline A., Zhu, Sujie, Aittokallio, Tero
Publicado 2022

Proteomic and Metabolomic Analysis of Bone Marrow and Plasma from Patients with Extramedullary Multiple Myeloma Identifies Distinct Protein and Metabolite Signatures

por Dunphy, Katie, Bazou, Despina, Henry, Michael, Meleady, Paula, Miettinen, Juho J., Heckman, Caroline A., Dowling, Paul, O’Gorman, Peter
Publicado 2023

Prognostic significance of esterase gene expression in multiple myeloma

por Kumari, Romika, Majumder, Muntasir Mamun, Lievonen, Juha, Silvennoinen, Raija, Anttila, Pekka, Nupponen, Nina N., Lehmann, Fredrik, Heckman, Caroline A.
Publicado 2021

Next generation proteomics with drug sensitivity screening identifies sub-clones informing therapeutic and drug development strategies for multiple myeloma patients

por Tierney, Ciara, Bazou, Despina, Majumder, Muntasir M., Anttila, Pekka, Silvennoinen, Raija, Heckman, Caroline A., Dowling, Paul, O’Gorman, Peter
Publicado 2021

A germline exome analysis reveals harmful POT1 variants in multiple myeloma patients and families

por Hakkarainen, Marja, Koski, Jessica R., Heckman, Caroline A., Anttila, Pekka, Silvennoinen, Raija, Lievonen, Juha, Kilpivaara, Outi, Wartiovaara‐Kautto, Ulla
Publicado 2022

Large registry-based analysis of genetic predisposition to tuberculosis identifies genetic risk factors at HLA

por Tervi, Anniina, Junna, Nella, Broberg, Martin, Jones, Samuel E, Strausz, Satu, Kreivi, Hanna-Riikka, Heckman, Caroline A, Ollila, Hanna M
Publicado 2022

Deep Immune Profiling of Multiple Myeloma at Diagnosis and under Lenalidomide Maintenance Therapy

por Luoma, Sini, Sergeev, Philipp, Javarappa, Komal Kumar, Öhman, Tiina J., Varjosalo, Markku, Säily, Marjaana, Anttila, Pekka, Sankelo, Marja, Partanen, Anu, Nihtinen, Anne, Heckman, Caroline A., Silvennoinen, Raija
Publicado 2023

The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomains

por Alzrigat, Mohammad, Párraga, Alba Atienza, Majumder, Muntasir Mamun, Ma, Anqi, Jin, Jian, Österborg, Anders, Nahi, Hareth, Nilsson, Kenneth, Heckman, Caroline A., Öberg, Fredrik, Kalushkova, Antonia, Jernberg-Wiklund, Helena
Publicado 2017