Sequence Features of Mitochondrial Transporter Protein Families

por Gyimesi, Gergely, Hediger, Matthias A.
Publicado 2020

Systematic in silico discovery of novel solute carrier-like proteins from proteomes

por Gyimesi, Gergely, Hediger, Matthias A.
Publicado 2022

Transporter-Mediated Drug Delivery

por Gyimesi, Gergely, Hediger, Matthias A.
Publicado 2023

A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters

por Pujol-Giménez, Jonai, Hediger, Matthias A., Gyimesi, Gergely
Publicado 2017

Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application

por Gyimesi, Gergely, Pujol-Giménez, Jonai, Kanai, Yoshikatsu, Hediger, Matthias A.
Publicado 2020

The ABCs of membrane transporters in health and disease (SLC series): Introduction()()

por Hediger, Matthias A., Clémençon, Benjamin, Burrier, Robert E., Bruford, Elspeth A.
Publicado 2013

Applications of the Microscale Thermophoresis Binding Assay in COVID-19 Research

por Nydegger, Damian T., Pujol-Giménez, Jonai, Kandasamy, Palanivel, Vogt, Bruno, Hediger, Matthias A.
Publicado 2023

Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2)

por Gyimesi, Gergely, Albano, Giuseppe, Fuster, Daniel G., Hediger, Matthias A., Pujol-Giménez, Jonai
Publicado 2019

Functional characterization of a highly specific l-arabinose transporter from Trichoderma reesei

por Havukainen, Sami, Pujol-Giménez, Jonai, Valkonen, Mari, Hediger, Matthias A., Landowski, Christopher P.
Publicado 2021

The Less Well-Known Little Brothers: The SLC9B/NHA Sodium Proton Exchanger Subfamily—Structure, Function, Regulation and Potential Drug-Target Approaches

por Anderegg, Manuel A., Gyimesi, Gergely, Ho, Tin Manh, Hediger, Matthias A., Fuster, Daniel G.
Publicado 2022

Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds

por Manatschal, Cristina, Pujol-Giménez, Jonai, Poirier, Marion, Reymond, Jean-Louis, Hediger, Matthias A, Dutzler, Raimund
Publicado 2019

Electrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei

por Havukainen, Sami, Pujol-Giménez, Jonai, Valkonen, Mari, Westerholm-Parvinen, Ann, Hediger, Matthias A., Landowski, Christopher P.
Publicado 2021

Frog Oocytes to Unveil the Structure and Supramolecular Organization of Human Transport Proteins

por Bergeron, Marc J., Boggavarapu, Rajendra, Meury, Marcel, Ucurum, Zöhre, Caron, Luc, Isenring, Paul, Hediger, Matthias A., Fotiadis, Dimitrios
Publicado 2011

Expression, Purification, and Structural Insights for the Human Uric Acid Transporter, GLUT9, Using the Xenopus laevis Oocytes System

por Clémençon, Benjamin, Lüscher, Benjamin P., Fine, Michael, Baumann, Marc U., Surbek, Daniel V., Bonny, Olivier, Hediger, Matthias A.
Publicado 2014

Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1

por Kandasamy, Palanivel, Zlobec, Inti, Nydegger, Damian T., Pujol‐Giménez, Jonai, Bhardwaj, Rajesh, Shirasawa, Senji, Tsunoda, Toshiyuki, Hediger, Matthias A.
Publicado 2021

Pyrazolyl-pyrimidones inhibit the function of human solute carrier protein SLC11A2 (hDMT1) by metal chelation

por Poirier, Marion, Pujol-Giménez, Jonai, Manatschal, Cristina, Bühlmann, Sven, Embaby, Ahmed, Javor, Sacha, Hediger, Matthias A., Reymond, Jean-Louis
Publicado 2020

Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cance...

por Schild, Achille, Bhardwaj, Rajesh, Wenger, Nicolas, Tscherrig, Dominic, Kandasamy, Palanivel, Dernič, Jan, Baur, Roland, Peinelt, Christine, Hediger, Matthias A., Lochner, Martin
Publicado 2020

Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor

por Cunha, Micael Rodrigues, Bhardwaj, Rajesh, Carrel, Aline Lucie, Lindinger, Sonja, Romanin, Christoph, Parise-Filho, Roberto, Hediger, Matthias A., Reymond, Jean-Louis
Publicado 2020

The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca(2+) entry

por Kar, Pulak, Lin, Yu-Ping, Bhardwaj, Rajesh, Tucker, Charles J., Bird, Gary S., Hediger, Matthias A., Monico, Carina, Amin, Nader, Parekh, Anant B.
Publicado 2021

Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library

por Pujol‐Giménez, Jonai, Poirier, Marion, Bühlmann, Sven, Schuppisser, Céline, Bhardwaj, Rajesh, Awale, Mahendra, Visini, Ricardo, Javor, Sacha, Hediger, Matthias A., Reymond, Jean‐Louis
Publicado 2021