Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy

por Mamaghani, Shadi, Patel, Satish, Hedley, David W
Publicado 2009

Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined with rapamycin in human orthotopic primary pancreatic cancer xenografts

por Chang, Qing, Chapman, Mark S, Miner, Jeffrey N, Hedley, David W
Publicado 2010

Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis

por Pham, Nhu-An, Schwock, Joerg, Iakovlev, Vladimir, Pond, Greg, Hedley, David W, Tsao, Ming-Sound
Publicado 2008

Assessment of Hypoxia in the Stroma of Patient-Derived Pancreatic Tumor Xenografts

por Lohse, Ines, Lourenco, Corey, Ibrahimov, Emin, Pintilie, Melania, Tsao, Ming-Sound, Hedley, David W.
Publicado 2014

Activity of the novel polo-like kinase 4 inhibitor CFI-400945 in pancreatic cancer patient-derived xenografts

por Lohse, Ines, Mason, Jacqueline, Mary, Pinjiang Cao, Pintilie, Melania, Bray, Mark, Hedley, David W
Publicado 2016

Biodistribution of cisplatin revealed by imaging mass cytometry identifies extensive collagen binding in tumor and normal tissues

por Chang, Qing, Ornatsky, Olga I., Siddiqui, Iram, Straus, Rita, Baranov, Vladimir I., Hedley, David W.
Publicado 2016

Effects of Combined Treatment with Ionizing Radiation and the PARP Inhibitor Olaparib in BRCA Mutant and Wild Type Patient-Derived Pancreatic Cancer Xenografts

por Lohse, Ines, Kumareswaran, Ramya, Cao, Pinjiang, Pitcher, Bethany, Gallinger, Steven, Bristow, Robert G., Hedley, David W.
Publicado 2016

Quantitative image analysis of immunohistochemical stains using a CMYK color model

por Pham, Nhu-An, Morrison, Andrew, Schwock, Joerg, Aviel-Ronen, Sarit, Iakovlev, Vladimir, Tsao, Ming-Sound, Ho, James, Hedley, David W
Publicado 2007

SNAI1 expression and the mesenchymal phenotype: an immunohistochemical study performed on 46 cases of oral squamous cell carcinoma

por Schwock, Joerg, Bradley, Grace, Ho, James C, Perez-Ordonez, Bayardo, Hedley, David W, Irish, Jonathan C, Geddie, William R
Publicado 2010

Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302

por Lohse, Ines, Rasowski, Joanna, Cao, Pinjiang, Pintilie, Melania, Do, Trevor, Tsao, Ming-Sound, Hill, Richard P., Hedley, David W.
Publicado 2016

Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to TRAIL-Induced Apoptosis

por Mamaghani, Shadi, Simpson, Craig D., Cao, Pinjiang M., Cheung, May, Chow, Sue, Bandarchi, Bizhan, Schimmer, Aaron D., Hedley, David W.
Publicado 2012

Impact of tissue transport on PET hypoxia quantification in pancreatic tumours

por Taylor, Edward, Gottwald, Jennifer, Yeung, Ivan, Keller, Harald, Milosevic, Michael, Dhani, Neesha C., Siddiqui, Iram, Hedley, David W., Jaffray, David A.
Publicado 2017

FOLFIRINOX for advanced pancreatic cancer: the Princess Margaret Cancer Centre experience

por Chllamma, Muralidharan K, Cook, Natalie, Dhani, Neesha C, Giby, Kazim, Dodd, Anna, Wang, Lisa, Hedley, David W, Moore, Malcolm J, Knox, Jennifer J
Publicado 2016

Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma

por Matkar, Pratiek N., Singh, Krishna Kumar, Rudenko, Dmitriy, Kim, Yu Jin, Kuliszewski, Michael A., Prud'homme, Gerald J., Hedley, David W., Leong-Poi, Howard
Publicado 2016

Quantifying Reoxygenation in Pancreatic Cancer During Stereotactic Body Radiotherapy

por Taylor, Edward, Zhou, Jitao, Lindsay, Patricia, Foltz, Warren, Cheung, May, Siddiqui, Iram, Hosni, Ali, Amir, Ahmed El, Kim, John, Hill, Richard P., Jaffray, David A., Hedley, David W.
Publicado 2020

Chromosomal instability as a prognostic marker in cervical cancer

por How, Christine, Bruce, Jeff, So, Jonathan, Pintilie, Melania, Haibe-Kains, Benjamin, Hui, Angela, Clarke, Blaise A, Hedley, David W, Hill, Richard P, Milosevic, Michael, Fyles, Anthony, Liu, Fei-Fei
Publicado 2015

Digital quantitative tissue image analysis of hypoxia in resected pancreatic ductal adenocarcinomas

por Siddiqui, Iram, Bilkey, Jade, McKee, Trevor D., Serra, Stefano, Pintilie, Melania, Do, Trevor, Xu, Jing, Tsao, Ming-Sound, Gallinger, Steve, Hill, Richard P., Hedley, David W., Dhani, Neesha C.
Publicado 2022

MicroRNA-196b Regulates the Homeobox B7-Vascular Endothelial Growth Factor Axis in Cervical Cancer

por How, Christine, Hui, Angela B. Y., Alajez, Nehad M., Shi, Wei, Boutros, Paul C., Clarke, Blaise A., Yan, Rui, Pintilie, Melania, Fyles, Anthony, Hedley, David W., Hill, Richard P., Milosevic, Michael, Liu, Fei-Fei
Publicado 2013

Developing a Prognostic Micro-RNA Signature for Human Cervical Carcinoma

por How, Christine, Pintilie, Melania, Bruce, Jeff P., Hui, Angela B. Y., Clarke, Blaise A., Wong, Philip, Yin, Shaoming, Yan, Rui, Waggott, Daryl, Boutros, Paul C., Fyles, Anthony, Hedley, David W., Hill, Richard P., Milosevic, Michael, Liu, Fei-Fei
Publicado 2015

Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers

por Pham, Nhu-An, Radulovich, Nikolina, Ibrahimov, Emin, Martins-Filho, Sebastiao N., Li, Quan, Pintilie, Melania, Weiss, Jessica, Raghavan, Vibha, Cabanero, Michael, Denroche, Robert E., Wilson, Julie M., Metran-Nascente, Cristiane, Borgida, Ayelet, Hutchinson, Shawn, Dodd, Anna, Begora, Michael, Chadwick, Dianne, Serra, Stefano, Knox, Jennifer J., Gallinger, Steven, Hedley, David W., Muthuswamy, Lakshmi, Tsao, Ming-Sound
Publicado 2021