Human FXR Regulates SHP Expression through Direct Binding to an LRH-1 Binding Site, Independent of an IR-1 and LRH-1

por Hoeke, Martijn O., Heegsma, Janette, Hoekstra, Mark, Moshage, Han, Faber, Klaas Nico
Publicado 2014

Growth differentiation factor 7 autocrine signaling promotes hepatic progenitor cell expansion in liver fibrosis

por Kong, Defu, Mourtzinos, Apostolos, Heegsma, Janette, Blokzijl, Hans, de Meijer, Vincent E., Faber, Klaas Nico
Publicado 2023

Plasma Levels of Retinol Binding Protein 4 Relate to Large VLDL and Small LDL Particles in Subjects with and without Type 2 Diabetes

por Wessel, Hanna, Saeed, Ali, Heegsma, Janette, Connelly, Margery A., Faber, Klaas Nico, Dullaart, Robin P. F.
Publicado 2019

Hibernator-Derived Cells Show Superior Protection and Survival in Hypothermia Compared to Non-Hibernator Cells

por Hendriks, Koen D.W., Joschko, Christian P., Hoogstra-Berends, Femke, Heegsma, Janette, Faber, Klaas-Nico, Henning, Robert H.
Publicado 2020

Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes

por Saeed, Ali, Bartuzi, Paulina, Heegsma, Janette, Dekker, Daphne, Kloosterhuis, Niels, de Bruin, Alain, Jonker, Johan W., van de Sluis, Bart, Faber, Klaas Nico
Publicado 2020

Farnesoid X receptor and bile acids regulate vitamin A storage

por Saeed, Ali, Yang, Jing, Heegsma, Janette, Groen, Albert K., van Mil, Saskia W. C., Paulusma, Coen C., Zhou, Lu, Wang, Bangmao, Faber, Klaas Nico
Publicado 2019

Simultaneous Induction of Glycolysis and Oxidative Phosphorylation during Activation of Hepatic Stellate Cells Reveals Novel Mitochondrial Targets to Treat Liver Fibrosis

por Smith-Cortinez, Natalia, van Eunen, Karen, Heegsma, Janette, Serna-Salas, Sandra Alejandra, Sydor, Svenja, Bechmann, Lars P., Moshage, Han, Bakker, Barbara M., Faber, Klaas Nico
Publicado 2020

Glycogen storage disease type 1a is associated with disturbed vitamin A metabolism and elevated serum retinol levels

por Saeed, Ali, Hoogerland, Joanne A, Wessel, Hanna, Heegsma, Janette, Derks, Terry G J, van der Veer, Eveline, Mithieux, Gilles, Rajas, Fabienne, Oosterveer, Maaike H, Faber, Klaas Nico
Publicado 2020

Mitochondrial DNA methylation in metabolic associated fatty liver disease

por Mposhi, Archibold, Cortés-Mancera, Fabian, Heegsma, Janette, de Meijer, Vincent E., van de Sluis, Bart, Sydor, Svenja, Bechmann, Lars P., Theys, Claudia, de Rijk, Peter, De Pooter, Tim, Vanden Berghe, Wim, İnce, İkbal Agah, Faber, Klaas Nico, Rots, Marianne G.
Publicado 2023

Disruption of vitamin A homeostasis by the biocide tetrakis(hydroxymethyl) phosphonium sulphate in pregnant rabbits

por Estrada‐Ortiz, Natalia, Starokozhko, Viktoriia, van Steenwijk, Hidde, van der Heide, Cor, Permentier, Hjalmar, van Heemskerk, Lisanne, Prins, Grietje Harmanna, Heegsma, Janette, Faber, Klaas Nico, Bressers, Steffi, Steiblen, Guy, de Groot, Antoinette, Groome, Steve, van Miert, Erik, Groothuis, Geny, de Graaf, Inge Anne Maria
Publicado 2022

A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease

por Bourgonje, Arno R., von Martels, Julius Z. H., Gabriëls, Ruben Y., Blokzijl, Tjasso, Buist-Homan, Manon, Heegsma, Janette, Jansen, Bernadien H., van Dullemen, Hendrik M., Festen, Eleonora A. M., ter Steege, Rinze W. F., Visschedijk, Marijn C., Weersma, Rinse K., de Vos, Paul, Faber, Klaas Nico, Dijkstra, Gerard
Publicado 2019