Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade

por Gaißler, Andrea, Meldgaard, Trine Sundebo, Heeke, Christina, Babaei, Sepideh, Tvingsholm, Siri Amanda, Bochem, Jonas, Spreuer, Janine, Amaral, Teresa, Wagner, Nikolaus Benjamin, Klein, Reinhild, Meier, Friedegund, Garbe, Claus, Eigentler, Thomas K., Pawelec, Graham, Claassen, Manfred, Weide, Benjamin, Hadrup, Sine Reker, Wistuba-Hamprecht, Kilian
Publicado 2022

Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions

por Sucker, Antje, Zhao, Fang, Pieper, Natalia, Heeke, Christina, Maltaner, Raffaela, Stadtler, Nadine, Real, Birgit, Bielefeld, Nicola, Howe, Sebastian, Weide, Benjamin, Gutzmer, Ralf, Utikal, Jochen, Loquai, Carmen, Gogas, Helen, Klein-Hitpass, Ludger, Zeschnigk, Michael, Westendorf, Astrid M., Trilling, Mirko, Horn, Susanne, Schilling, Bastian, Schadendorf, Dirk, Griewank, Klaus G., Paschen, Annette
Publicado 2017

Neoantigen-reactive CD8(+) T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma

por Kristensen, Nikolaj Pagh, Heeke, Christina, Tvingsholm, Siri A., Borch, Annie, Draghi, Arianna, Crowther, Michael D., Carri, Ibel, Munk, Kamilla K., Holm, Jeppe Sejerø, Bjerregaard, Anne-Mette, Bentzen, Amalie Kai, Marquard, Andrea M., Szallasi, Zoltan, McGranahan, Nicholas, Andersen, Rikke, Nielsen, Morten, Jönsson, Göran B., Donia, Marco, Svane, Inge Marie, Hadrup, Sine Reker
Publicado 2022

TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy

por Tvingsholm, Siri Amanda, Frej, Marcus Svensson, Rafa, Vibeke Mindahl, Hansen, Ulla Kring, Ormhøj, Maria, Tyron, Alexander, Jensen, Agnete W P, Kadivar, Mohammad, Bentzen, Amalie Kai, Munk, Kamilla K, Aasbjerg, Gitte N, Ternander, Jeppe S H, Heeke, Christina, Tamhane, Tripti, Schmess, Christian, Funt, Samuel A., Kjeldsen, Julie Westerlin, Kverneland, Anders Handrup, Met, Özcan, Draghi, Arianna, Jakobsen, Søren Nyboe, Donia, Marco, Marie Svane, Inge, Hadrup, Sine Reker
Publicado 2023