Chimeric Antigen Receptor (CAR) Regulatory T-Cells in Solid Organ Transplantation

por Gille, Ilse, Claas, Frans H. J., Haasnoot, Geert W., Heemskerk, Mirjam H. M., Heidt, Sebastiaan
Publicado 2022

A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies

por Rosskopf, Sandra, Leitner, Judith, Paster, Wolfgang, Morton, Laura T., Hagedoorn, Renate S., Steinberger, Peter, Heemskerk, Mirjam H.M.
Publicado 2018

Extracellular Domains of CD8α and CD8ß Subunits Are Sufficient for HLA Class I Restricted Helper Functions of TCR-Engineered CD4(+) T Cells

por van Loenen, Marleen M., Hagedoorn, Renate S., de Boer, Renate, Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Publicado 2013

Reprogramming of Virus-specific T Cells into Leukemia-reactive T Cells Using T Cell Receptor Gene Transfer

por Heemskerk, Mirjam H.M., Hoogeboom, Manja, Hagedoorn, Renate, Kester, Michel G.D., Willemze, Roel, Falkenburg, J.H. Frederik
Publicado 2004

Uptake of HLA Alloantigens via CD89 and CD206 Does Not Enhance Antigen Presentation by Indirect Allorecognition

por Breman, Eytan, Ruben, Jurjen M., Franken, Kees L., Heemskerk, Mirjam H. M., Roelen, Dave L., Claas, Frans H., van Kooten, Cees
Publicado 2016

Inhibition of SUMOylation enhances DNA hypomethylating drug efficacy to reduce outgrowth of hematopoietic malignancies

por Kroonen, Jessie S., de Graaf, Ilona J., Kumar, Sumit, Remst, Dennis F. G., Wouters, Anne K., Heemskerk, Mirjam H. M., Vertegaal, Alfred C. O.
Publicado 2023

Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

por Heemskerk, Mirjam H.M., Blom, Bianca, Nolan, Garry, Stegmann, Alexander P.A., Bakker, Arjen Q., Weijer, Kees, Res, Pieter C.M., Spits, Hergen
Publicado 1997

Transduction of Human T Cells with a Novel T-Cell Receptor Confers Anti-HCV Reactivity

por Zhang, Yi, Liu, Yeuying, Moxley, Kelly M., Golden-Mason, Lucy, Hughes, Michael G., Liu, Tongxin, Heemskerk, Mirjam H. M., Rosen, Hugo R., Nishimura, Michael I.
Publicado 2010

Combining BCMA-targeting CAR T cells with TCR-engineered T-cell therapy to prevent immune escape of multiple myeloma

por Wachsmann, Tassilo L. A., Meeuwsen, Miranda H., Remst, Dennis F. G., Buchner, Karen, Wouters, Anne K., Hagedoorn, Renate S., Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Publicado 2023

High-Throughput Identification of Potential Minor Histocompatibility Antigens by MHC Tetramer-Based Screening: Feasibility and Limitations

por Hombrink, Pleun, Hadrup, Sine R., Bakker, Arne, Kester, Michel G. D., Falkenburg, J. H. Frederik, von dem Borne, Peter A., Schumacher, Ton N. M., Heemskerk, Mirjam H. M.
Publicado 2011

T cell receptor engineering of primary NK cells to therapeutically target tumors and tumor immune evasion

por Morton, Laura T, Wachsmann, Tassilo L A, Meeuwsen, Miranda H, Wouters, Anne K, Remst, Dennis F G, van Loenen, Marleen M, Falkenburg, J H Frederik, Heemskerk, Mirjam H M
Publicado 2022

Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma

por Spel, Lotte, Boelens, Jaap-Jan, van der Steen, Dirk M., Blokland, Nina J.G., van Noesel, Max M., Molenaar, Jan J., Heemskerk, Mirjam H.M., Boes, Marianne, Nierkens, Stefan
Publicado 2015

Convalescent Plasma in a Patient with Protracted COVID-19 and Secondary Hypogammaglobulinemia Due to Chronic Lymphocytic Leukemia: Buying Time to Develop Immunity?

por Hanssen, Jaap L. J., Stienstra, Johan, Boers, Stefan A., Pothast, Cilia R., Zaaijer, Hans L., Tjon, Jennifer M., Heemskerk, Mirjam H. M., Feltkamp, Mariet C. W., Arend, Sandra M.
Publicado 2021

Identification of Functional HLA-A*01:01–Restricted Epstein-Barr Latent Membrane Protein 2–Specific T-Cell Receptors( )

por Huisman, Wesley, Gille, Ilse, van der Maarel, Lieve E, Hageman, Lois, Morton, Laura T, de Jong, Rob C M, Heemskerk, Mirjam H M, Amsen, Derk, Falkenburg, J H Frederik, Jedema, Inge
Publicado 2020

Human iPSC-derived preclinical models to identify toxicity of tumor-specific T cells with clinical potential

por van Amerongen, Rosa A., Morton, Laura T., Chaudhari, Umesh G., Remst, Dennis F.G., Hagedoorn, Renate S., van den Berg, Cathelijne W., Freund, Christian, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado 2023

Comparing CAR and TCR engineered T cell performance as a function of tumor cell exposure

por Wachsmann, Tassilo L. A., Wouters, Anne K., Remst, Dennis F. G., Hagedoorn, Renate S., Meeuwsen, Miranda H., van Diest, Eline, Leusen, Jeanette, Kuball, Jürgen, Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Publicado 2022

Identification of non-mutated neoantigens presented by TAP-deficient tumors

por Marijt, Koen A., Blijleven, Laura, Verdegaal, Els M.E., Kester, Michel G., Kowalewski, Daniel J., Rammensee, Hans-Georg, Stevanović, Stefan, Heemskerk, Mirjam H.M., van der Burg, Sjoerd H., van Hall, Thorbald
Publicado 2018

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer

por Jahn, Lorenz, Hagedoorn, Renate S., van der Steen, Dirk M., Hombrink, Pleun, Kester, Michel G.D., Schoonakker, Marjolein P., de Ridder, Daniëlle, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado 2016

Generation of CD20-specific TCRs for TCR gene therapy of CD20(low) B-cell malignancies insusceptible to CD20-targeting antibodies

por Jahn, Lorenz, van der Steen, Dirk M., Hagedoorn, Renate S., Hombrink, Pleun, Kester, Michel G.D., Schoonakker, Marjolein P., de Ridder, Daniëlle, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado 2016

Characterization of circulating T-, NK-, and NKT cell subsets in patients with colorectal cancer: the peripheral blood immune cell profile

por Krijgsman, Daniëlle, de Vries, Natasja L., Skovbo, Anni, Andersen, Morten N., Swets, Marloes, Bastiaannet, Esther, Vahrmeijer, Alexander L., van de Velde, Cornelis J. H., Heemskerk, Mirjam H. M., Hokland, Marianne, Kuppen, Peter J. K.
Publicado 2019