Text Mining and Data Modeling of Karyotypes to aid in Drug Repurposing Efforts

por Abrams, Zachary B., Peabody, Andrea L., Heerema, Nyla A., Payne, Philip R. O.
Publicado 2015

Promyelocytic Leukemia with No Retinoic Acid Receptor Alpha Abnormality but with RUNX1T1 Insertion to Chromosome 7q: A Classification and Management Dilemma

por Overholt, Kathleen, Guinipero, Terri L., Heerema, Nyla A., Loken, Michael R., Kahwash, Samir B.
Publicado 2015

Novel t(1;2)(p36.1;q23) and t(7;19)(q32;q13.3) chromosomal translocations in ischemic fasciitis: expanding the spectrum of pseudosarcomatous lesions with clonal pathogenetic link

por Sachak, Taha, Heerema, Nyla A., Mayerson, Joel, Payne, Jason E., Parwani, Anil, Iwenofu, O. Hans
Publicado 2018

CytoGPS: a web-enabled karyotype analysis tool for cytogenetics

por Abrams, Zachary B, Zhang, Lin, Abruzzo, Lynne V, Heerema, Nyla A, Li, Suli, Dillon, Tom, Rodriguez, Ricky, Coombes, Kevin R, Payne, Philip R O
Publicado 2019

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia

por Yeh, Yuh-Ying, Chen, Rong, Hessler, Joshua, Mahoney, Emilia, Lehman, Amy M., Heerema, Nyla A., Grever, Michael R., Plunkett, William, Byrd, John C., Johnson, Amy J.
Publicado 2014

VpreB surrogate light chain expression in B-lineage ALL: a report from the Children’s Oncology Group

por Winter, Stuart S., McCaustland, Amanda, Qu, Chunxu, Simeona, No’eau, Heerema, Nyla A., Carroll, Andrew J., Wood, Brent L., Gheorghe, Gabriela, Mullighan, Charles G., Wilson, Bridget S.
Publicado 2022

The Dohner fluorescence in situ hybridization prognostic classification of chronic lymphocytic leukaemia (CLL): the CLL Research Consortium experience

por Van Dyke, Daniel L., Werner, Lillian, Rassenti, Laura Z., Neuberg, Donna, Ghia, Emanuella, Heerema, Nyla A., Dal Cin, Paola, Dell Aquila, Marie, Sreekantaiah, Chandrika, Greaves, Andrew W., Kipps, Thomas J., Kay, Neil E.
Publicado 2016

Prognostic significance of translocations in the presence of mutated IGHV and of cytogenetic complexity at diagnosis of chronic lymphocytic leukemia

por Heerema, Nyla A., Muthusamy, Natarajan, Zhao, Qiuhong, Ruppert, Amy S., Breidenbach, Heather, Andritsos, Leslie A., Grever, Michael R., Maddocks, Kami J., Woyach, Jennifer, Awan, Farrukh, Long, Meixiao, Gordon, Amber, Coombes, Caitlin, Byrd, John C.
Publicado 2020

Impact of Targeted Therapy on Outcome of Chronic Lymphocytic Leukemia Patients with Relapsed Del(17p13.1) Karyotype at a Single Center

por Stephens, Deborah M., Ruppert, Amy S., Jones, Jeffrey, Woyach, Jennifer, Maddocks, Kami, Jaglowski, Samantha, Andritsos, Leslie A., Flynn, Joseph M., Grever, Michael R., Lozanski, Gerard, Johnson, Amy J., Muthusamy, Natarajan, Heerema, Nyla A., Byrd, John C.
Publicado 2014

Ethnic Variation of TET2 SNP rs2454206 and Association with Clinical Outcome in Childhood AML: A Report from the Children’s Oncology Group

por Kutny, Matthew A., Alonzo, Todd A., Gamazon, Eric R., Gerbing, Robert B., Geraghty, Daniel, Lange, Beverly, Heerema, Nyla A., Sung, Lillian, Aplenc, Richard, Franklin, Janet, Raimondi, Susana C., Hirsch, Betsy A., Konkashbaev, Anuar, Cox, Nancy J., Onel, Kenan, Gamis, Alan S., Meshinchi, Soheil
Publicado 2015

Evaluation of 230 patients with relapsed/refractory deletion 17p chronic lymphocytic leukaemia treated with ibrutinib from 3 clinical trials

por Jones, Jeffrey, Mato, Anthony, Coutre, Steven, Byrd, John C., Furman, Richard R., Hillmen, Peter, Osterborg, Anders, Tam, Constantine, Stilgenbauer, Stephan, Wierda, William G., Heerema, Nyla A., Eckert, Karl, Clow, Fong, Zhou, Cathy, Chu, Alvina D., James, Danelle F., O'Brien, Susan M.
Publicado 2018

Outstanding outcomes in infants with KMT2Agermline acute lymphoblastic leukemia treated with chemotherapy alone: results of the Children’s Oncology Group AALL0631 trial

por Guest, Erin M., Kairalla, John A., Hilden, Joanne M., Dreyer, ZoAnn E., Carroll, Andrew J., Heerema, Nyla A., Wang, Cindy Y., Devidas, Meenakshi, Gore, Lia, Salzer, Wanda L., Winick, Naomi J., Carroll, William L., Raetz, Elizabeth A., Borowitz, Michael, Loh, Mignon L., Hunger, Stephen P., Brown, Patrick A.
Publicado 2022

Precancerous Stem Cells Have the Potential for both Benign and Malignant Differentiation

por Chen, Li, Shen, Rulong, Ye, Yin, Pu, Xin-An, Liu, Xingluo, Duan, Wenrui, Wen, Jing, Zimmerer, Jason, Wang, Ying, Liu, Yan, Lasky, Larry C., Heerema, Nyla A., Perrotti, Danilo, Ozato, Keiko, Kuramochi-Miyagawa, Satomi, Nakano, Toru, Yates, Allen J., Carson III, William E., Lin, Haifan, Barsky, Sanford H., Gao, Jian-Xin
Publicado 2007

Characterization of a New Chronic Lymphocytic Leukemia Cell Line for Mechanistic In Vitro and In Vivo Studies Relevant to Disease

por Hertlein, Erin, Beckwith, Kyle A., Lozanski, Gerard, Chen, Timothy L., Towns, William H., Johnson, Amy J., Lehman, Amy, Ruppert, Amy S., Bolon, Brad, Andritsos, Leslie, Lozanski, Arletta, Rassenti, Laura, Zhao, Weiqiang, Jarvinen, Tiina M., Senter, Leigha, Croce, Carlo M., Symer, David E., de la Chapelle, Albert, Heerema, Nyla A., Byrd, John C.
Publicado 2013

A novel regimen for relapsed/refractory adult acute myeloid leukemia using a KMT2A partial tandem duplication targeted therapy: results of phase 1 study NCI 8485

por Mims, Alice S., Mishra, Anjali, Orwick, Shelley, Blachly, James, Klisovic, Rebecca B., Garzon, Ramiro, Walker, Alison R., Devine, Steven M., Walsh, Katherine J., Vasu, Sumithira, Whitman, Susan, Marcucci, Guido, Jones, Daniel, Heerema, Nyla A., Lozanski, Gerard, Caligiuri, Michael A., Bloomfield, Clara D., Byrd, John C., Piekarz, Richard, Grever, Michael R., Blum, William
Publicado 2018

Replacing cyclophosphamide/cytarabine/mercaptopurine with cyclophosphamide/etoposide during consolidation/delayed intensification does not improve outcome for pediatric B-cell acut...

por Burke, Michael J., Salzer, Wanda L., Devidas, Meenakshi, Dai, Yunfeng, Gore, Lia, Hilden, Joanne M., Larsen, Eric, Rabin, Karen R., Zweidler-McKay, Patrick A., Borowitz, Michael J., Wood, Brent, Heerema, Nyla A., Carroll, Andrew J., Winick, Naomi, Carroll, William L., Raetz, Elizabeth A., Loh, Mignon L., Hunger, Stephen P.
Publicado 2019

KMT2A partner genes in infant acute lymphoblastic leukemia have prognostic significance and correlate with age, white blood cell count, sex, and central nervous system involvement:...

por Robinson, Blaine W., Kairalla, John A., Devidas, Meenakshi, Carroll, Andrew J., Harvey, Richard C., Heerema, Nyla A., Willman, Cheryl L., Ball, Amanda R., Woods, Elliot C., Ballantyne, Nancy C., Urtishak, Karen A., Behm, Frederick G., Reaman, Gregory H., Hilden, Joanne M., Camitta, Bruce M., Winick, Naomi J., Pullen, Jeanette, Carroll, William L., Hunger, Stephen P., Dreyer, ZoAnn E., Felix, Carolyn A.
Publicado 2023

Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia

por Walker, Janek S., Hing, Zachary A., Sher, Steven, Cronin, James, Williams, Katie, Harrington, Bonnie, Skinner, Jordan N., Cempre, Casey B., Gregory, Charles T., Pan, Alexander, Yano, Max, Beaver, Larry P., Walker, Brandi R., Labanowska, Jadwiga M., Heerema, Nyla A., Mrózek, Krzysztof, Woyach, Jennifer A., Ruppert, Amy S., Lehman, Amy, Ozer, Hatice Gulcin, Coppola, Vincenzo, Yan, Pearlly, Byrd, John C., Blachly, James S., Lapalombella, Rosa
Publicado 2021

Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq

por Saygin, Caner, Hu, Eileen, Zhang, Pu, Sher, Steven, Lozanski, Arletta, Doong, Tzyy-Jye, Nicolet, Deedra, Orwick, Shelley, Labanowska, Jadwiga, Skinner, Jordan N., Cempre, Casey, Kauffman, Tierney, Goettl, Virginia M., Heerema, Nyla A., Abruzzo, Lynne, Miller, Cecelia, Lapalombella, Rosa, Behbehani, Gregory, Mims, Alice S., Larkin, Karilyn, Grieselhuber, Nicole, Walker, Alison, Bhatnagar, Bhavana, Bloomfield, Clara D., Byrd, John C., Lozanski, Gerard, Blachly, James S.
Publicado 2021

Correction: Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq

por Saygin, Caner, Hu, Eileen, Zhang, Pu, Sher, Steven, Lozanski, Arletta, Doong, Tzyy-Jye, Nicolet, Deedra, Orwick, Shelley, Labanowska, Jadwiga, Skinner, Jordan N., Cempre, Casey, Kauffman, Tierney, Goettl, Virginia M., Heerema, Nyla A., Abruzzo, Lynne, Miller, Cecelia, Lapalombella, Rosa, Behbehani, Gregory, Mims, Alice S., Larkin, Karilyn, Grieselhuber, Nicole, Walker, Alison, Bhatnagar, Bhavana, Bloomfield, Clara D., Byrd, John C., Lozanski, Gerard, Blachly, James S.
Publicado 2021