Cell-Type Dependent Regulation of the Electrogenic Na(+)/HCO(3)(−) Cotransporter 1 (NBCe1) by Hypoxia and Acidosis in Glioblastoma

por Giannaki, Marina, Ruf, Debora E., Pfeifer, Emilie, Everaerts, Katharina, Heiland, Dieter H., Schnell, Oliver, Rose, Christine R., Roussa, Eleni
Publicado 2022

c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

por Heiland, Dieter H, Ferrarese, Roberto, Claus, Rainer, Dai, Fangping, Masilamani, Anie P, Kling, Eva, Weyerbrock, Astrid, Kling, Teresia, Nelander, Sven, Carro, Maria S
Publicado 2016

Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence

por Andrieux, Geoffroy, Das, Tonmoy, Griffin, Michaela, Straehle, Jakob, Paine, Simon M. L., Beck, Jürgen, Boerries, Melanie, Heiland, Dieter H., Smith, Stuart J., Rahman, Ruman, Chakraborty, Sajib
Publicado 2023

Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism

por Masilamani, Anie P., Schulzki, Rana, Yuan, Shuai, Haase, Ira V., Kling, Eva, Dewes, Franziska, Andrieux, Geoffroy, Börries, Melanie, Schnell, Oliver, Heiland, Dieter H., Schilling, Oliver, Ferrarese, Roberto, Carro, Maria S.
Publicado 2022

Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma

por Wurm, Julian, Behringer, Simon P., Ravi, Vidhya M., Joseph, Kevin, Neidert, Nicolas, Maier, Julian P., Doria-Medina, Roberto, Follo, Marie, Delev, Daniel, Pfeifer, Dietmar, Beck, Jürgen, Sankowski, Roman, Schnell, Oliver, Heiland, Dieter H.
Publicado 2019

Characterization of longitudinal transformation of T2-hyperintensity in oligodendroglioma

por Heiland, Dieter H., Ohle, Robin, Cipriani, Debora, Franco, Pamela, Delev, Daniel, Behriger, Simon P., Kellner, Elias, Petrova, Gergana, Neidert, Nicolas, Mader, Irina, Nuñez, Mateo Fariña, Urbach, Horst, Sankowski, Roman, Beck, Jürgen, Schnell, Oliver
Publicado 2020

Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production

por Perrault, Ella N., Shireman, Jack M., Ali, Eunus S., Lin, Peiyu, Preddy, Isabelle, Park, Cheol, Budhiraja, Shreya, Baisiwala, Shivani, Dixit, Karan, James, C. David, Heiland, Dieter H, Ben-Sahra, Issam, Pott, Sebastian, Basu, Anindita, Miska, Jason, Ahmed, Atique U.
Publicado 2023

Inhibition of Intercellular Cytosolic Traffic via Gap Junctions Reinforces Lomustine-Induced Toxicity in Glioblastoma Independent of MGMT Promoter Methylation Status

por Schneider, Matthias, Potthoff, Anna-Laura, Evert, Bernd O., Dicks, Marius, Ehrentraut, Denise, Dolf, Andreas, Schmidt, Elena N. C., Schäfer, Niklas, Borger, Valeri, Pietsch, Torsten, Westhoff, Mike-Andrew, Güresir, Erdem, Waha, Andreas, Vatter, Hartmut, Heiland, Dieter H., Schuss, Patrick, Herrlinger, Ulrich
Publicado 2021

Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenog...

por Yabo, Yahaya A., Moreno-Sanchez, Pilar M., Pires-Afonso, Yolanda, Kaoma, Tony, Kyriakis, Dimitrios, Grzyb, Kamil, Poovathingal, Suresh K., Poli, Aurélie, Scafidi, Andrea, Muller, Arnaud, Toth, Reka, Oudin, Anaïs, Klink, Barbara, Berchem, Guy, Berthold, Christophe, Hertel, Frank, Mittelbronn, Michel, Heiland, Dieter H., Skupin, Alexander, Nazarov, Petr V., Niclou, Simone P., Michelucci, Alessandro, Golebiewska, Anna
Publicado 2023

Phase I/II trial of meclofenamate in progressive MGMT-methylated glioblastoma under temozolomide second-line therapy—the MecMeth/NOA-24 trial

por Zeyen, Thomas, Potthoff, Anna-Laura, Nemeth, Robert, Heiland, Dieter H., Burger, Michael C., Steinbach, Joachim P., Hau, Peter, Tabatabai, Ghazaleh, Glas, Martin, Schlegel, Uwe, Grauer, Oliver, Krex, Dietmar, Schnell, Oliver, Goldbrunner, Roland, Sabel, Michael, Thon, Niklas, Delev, Daniel, Clusmann, Hans, Seidel, Clemens, Güresir, Erdem, Schmid, Matthias, Schuss, Patrick, Giordano, Frank A., Radbruch, Alexander, Becker, Albert, Weller, Johannes, Schaub, Christina, Vatter, Hartmut, Schilling, Judith, Winkler, Frank, Herrlinger, Ulrich, Schneider, Matthias
Publicado 2022

Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability

por Drexler, Richard, Khatri, Robin, Sauvigny, Thomas, Mohme, Malte, Maire, Cecile L., Ryba, Alice, Zghaibeh, Yahya, Dührsen, Lasse, Salviano-Silva, Amanda, Lamszus, Katrin, Westphal, Manfred, Gempt, Jens, Wefers, Annika K., Neumann, Julia, Bode, Helena, Hausmann, Fabian, Huber, Tobias B., Bonn, Stefan, Jütten, Kerstin, Delev, Daniel, Weber, Katharina J., Harter, Patrick N., Onken, Julia, Vajkoczy, Peter, Capper, David, Wiestler, Benedikt, Weller, Michael, Snijder, Berend, Buck, Alicia, Weiss, Tobias, Keough, Michael B., Ni, Lijun, Monje, Michelle, Silverbush, Dana, Hovestadt, Volker, Suvà, Mario L., Krishna, Saritha, Hervey-Jumper, Shawn L., Schüller, Ulrich, Heiland, Dieter H., Hänzelmann, Sonja, Ricklefs, Franz L.
Publicado 2023