Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations

por San Millan, Alvaro, Heilbron, Karl, MacLean, R Craig
Publicado 2014

Fitness Is Strongly Influenced by Rare Mutations of Large Effect in a Microbial Mutation Accumulation Experiment

por Heilbron, Karl, Toll-Riera, Macarena, Kojadinovic, Mila, MacLean, R. Craig
Publicado 2014

Bidirectional relationship between olfaction and Parkinson’s disease

por Kim, Jonggeol J., Bandres-Ciga, Sara, Heilbron, Karl, Blauwendraat, Cornelis, Noyce, Alastair J.
Publicado 2023

Evaluating Lipid‐Lowering Drug Targets for Parkinson's Disease Prevention with Mendelian Randomization

por Williams, Dylan M., Bandres‐Ciga, Sara, Heilbron, Karl, Hinds, David, Noyce, Alastair J.
Publicado 2020

The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa

por Qi, Qin, Toll-Riera, Macarena, Heilbron, Karl, Preston, Gail M., MacLean, R. Craig
Publicado 2016

The Parkinson’s phenome—traits associated with Parkinson’s disease in a broadly phenotyped cohort

por Heilbron, Karl, Noyce, Alastair J., Fontanillas, Pierre, Alipanahi, Babak, Nalls, Mike A., Cannon, Paul
Publicado 2019

Analysis of rare Parkinson’s disease variants in millions of people

por Pitz, Vanessa, Makarious, Mary, Bandrés-Ciga, Sara, Iwaki, Hirotaka, Singleton, Andrew, Nalls, Mike, Heilbron, Karl, Blauwendraat, Cornelis
Publicado 2023

Advancing drug discovery using the power of the human genome

por Heilbron, Karl, Mozaffari, Sahar V, Vacic, Vladimir, Yue, Peng, Wang, Wei, Shi, Jingchunzi, Jubb, Adrian M, Pitts, Steven J, Wang, Xin
Publicado 2021

Unhealthy Behaviours and Risk of Parkinson’s Disease: A Mendelian Randomisation Study

por Heilbron, Karl, Jensen, Melanie P., Bandres-Ciga, Sara, Fontanillas, Pierre, Blauwendraat, Cornelis, Nalls, Mike A., Singleton, Andrew B., Smith, George Davey, Cannon, Paul, Noyce, Alastair J.
Publicado 2021

Correlations in sleeping patterns and circadian preference between spouses

por Richmond, Rebecca C., Howe, Laurence J., Heilbron, Karl, Jones, Samuel, Liu, Junxi, Wang, Xin, Weedon, Michael N., Rutter, Martin K., Lawlor, Deborah A., Davey Smith, George, Vetter, Céline
Publicado 2023

Parkinson’s disease determinants, prediction and gene–environment interactions in the UK Biobank

por Jacobs, Benjamin Meir, Belete, Daniel, Bestwick, Jonathan, Blauwendraat, Cornelis, Bandres-Ciga, Sara, Heilbron, Karl, Dobson, Ruth, Nalls, Mike A, Singleton, Andrew, Hardy, John, Giovannoni, Gavin, Lees, Andrew John, Schrag, Anette-Eleonore, Noyce, Alastair J
Publicado 2020

The Parkinson's Disease Mendelian Randomization Research Portal

por Noyce, Alastair J., Bandres‐Ciga, Sara, Kim, Jonggeol, Heilbron, Karl, Kia, Demis, Hemani, Gibran, Xue, Angli, Lawlor, Debbie A., Smith, George Davey, Duran, Raquel, Gan‐Or, Ziv, Blauwendraat, Cornelis, Gibbs, J. Raphael, Hinds, David A., Yang, Jian, Visscher, Peter, Cuzick, Jack, Morris, Huw, Hardy, John, Wood, Nicholas W., Nalls, Mike A., Singleton, Andrew B.
Publicado 2019

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

por Brumpton, Ben, Sanderson, Eleanor, Heilbron, Karl, Hartwig, Fernando Pires, Harrison, Sean, Vie, Gunnhild Åberge, Cho, Yoonsu, Howe, Laura D., Hughes, Amanda, Boomsma, Dorret I., Havdahl, Alexandra, Hopper, John, Neale, Michael, Nivard, Michel G., Pedersen, Nancy L., Reynolds, Chandra A., Tucker-Drob, Elliot M., Grotzinger, Andrew, Howe, Laurence, Morris, Tim, Li, Shuai, Auton, Adam, Windmeijer, Frank, Chen, Wei-Min, Bjørngaard, Johan Håkon, Hveem, Kristian, Willer, Cristen, Evans, David M., Kaprio, Jaakko, Davey Smith, George, Åsvold, Bjørn Olav, Hemani, Gibran, Davies, Neil M.
Publicado 2020

Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study and Meta-analysis

por Liao, Calwing, Castonguay, Charles-Etienne, Heilbron, Karl, Vuokila, Veikko, Medeiros, Miranda, Houle, Gabrielle, Akçimen, Fulya, Ross, Jay P., Catoire, Helene, Diez-Fairen, Monica, Kang, Jooeun, Mueller, Stefanie H., Girard, Simon L., Hopfner, Franziska, Lorenz, Delia, Clark, Lorraine N., Soto-Beasley, Alexandra I., Klebe, Stephan, Hallett, Mark, Wszolek, Zbigniew K., Pendziwiat, Manuela, Lorenzo-Betancor, Oswaldo, Seppi, Klaus, Berg, Daniela, Vilariño-Güell, Carles, Postuma, Ronald B., Bernard, Geneviève, Dupré, Nicolas, Jankovic, Joseph, Testa, Claudia M., Ross, Owen A., Arzberger, Thomas, Chouinard, Sylvain, Louis, Elan D., Mandich, Paola, Vitale, Carmine, Barone, Paolo, García-Martín, Elena, Alonso-Navarro, Hortensia, Agúndez, José A. G., Jiménez-Jiménez, Félix Javier, Pastor, Pau, Rajput, Alex, Deuschl, Günther, Kuhlenbaümer, Gregor, Meijer, Inge A., Dion, Patrick A., Rouleau, Guy A.
Publicado 2022

Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects

por Krohn, Lynne, Heilbron, Karl, Blauwendraat, Cornelis, Reynolds, Regina H., Yu, Eric, Senkevich, Konstantin, Rudakou, Uladzislau, Estiar, Mehrdad A., Gustavsson, Emil K., Brolin, Kajsa, Ruskey, Jennifer A., Freeman, Kathryn, Asayesh, Farnaz, Chia, Ruth, Arnulf, Isabelle, Hu, Michele T. M., Montplaisir, Jacques Y., Gagnon, Jean-François, Desautels, Alex, Dauvilliers, Yves, Gigli, Gian Luigi, Valente, Mariarosaria, Janes, Francesco, Bernardini, Andrea, Högl, Birgit, Stefani, Ambra, Ibrahim, Abubaker, Šonka, Karel, Kemlink, David, Oertel, Wolfgang, Janzen, Annette, Plazzi, Giuseppe, Biscarini, Francesco, Antelmi, Elena, Figorilli, Michela, Puligheddu, Monica, Mollenhauer, Brit, Trenkwalder, Claudia, Sixel-Döring, Friederike, Cochen De Cock, Valérie, Monaca, Christelle Charley, Heidbreder, Anna, Ferini-Strambi, Luigi, Dijkstra, Femke, Viaene, Mineke, Abril, Beatriz, Boeve, Bradley F., Scholz, Sonja W., Ryten, Mina, Bandres-Ciga, Sara, Noyce, Alastair, Cannon, Paul, Pihlstrøm, Lasse, Nalls, Mike A., Singleton, Andrew B., Rouleau, Guy A., Postuma, Ronald B., Gan-Or, Ziv
Publicado 2022