Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group

por Heilig, Christoph E, Löffler, Harald, Mahlknecht, Ulrich, Janssen, Johannes WG, Ho, Anthony D, Jauch, Anna, Krämer, Alwin
Publicado 2010

Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1

por Tibelius, Alexandra, Marhold, Joachim, Zentgraf, Hanswalter, Heilig, Christoph E., Neitzel, Heidemarie, Ducommun, Bernard, Rauch, Anita, Ho, Anthony D., Bartek, Jiri, Krämer, Alwin
Publicado 2009

Detection of Structural Variants in Circulating Cell-Free DNA from Sarcoma Patients Using Next Generation Sequencing

por Mc Connell, Lauren, Gazdova, Jana, Beck, Katja, Srivastava, Shambhavi, Harewood, Louise, Stewart, JP, Hübschmann, Daniel, Stenzinger, Albrecht, Glimm, Hanno, Heilig, Christoph E., Fröhling, Stefan, Gonzalez, David
Publicado 2020

Community-driven development of a modified progression-free survival ratio for precision oncology

por Mock, Andreas, Heilig, Christoph E, Kreutzfeldt, Simon, Huebschmann, Daniel, Heining, Christoph, Schröck, Evelin, Brors, Benedikt, Stenzinger, Albrecht, Jäger, Dirk, Schlenk, Richard, Glimm, Hanno, Fröhling, Stefan, Horak, Peter
Publicado 2019

Ruxolitinib is effective in the treatment of a patient with refractory T‐ALL

por Jaramillo, Sonia, Hennemann, Hannah, Horak, Peter, Teleanu, Veronica, Heilig, Christoph E., Hutter, Barbara, Stenzinger, Albrecht, Glimm, Hanno, Goeppert, Benjamin, Müller‐Tidow, Carsten, Fröhling, Stefan, Schönland, Stefan, Schlenk, Richard F.
Publicado 2020

Endometrial stromal sarcomas with BCOR‐rearrangement harbor MDM2 amplifications

por Kommoss, Felix KF, Chang, Kenneth TE, Stichel, Damian, Banito, Ana, Jones, David TW, Heilig, Christoph E, Fröhling, Stefan, Sahm, Felix, Stenzinger, Albrecht, Hartmann, Wolfgang, Mechtersheimer, Gunhild, Sinn, Hans‐Peter, Schmidt, Dietmar, Kommoss, Friedrich, von Deimling, Andreas, Koelsche, Christian
Publicado 2020

Haematopoietic stem cell transplantation in adult soft-tissue sarcoma: an analysis from the European Society for Blood and Marrow Transplantation

por Heilig, Christoph E, Badoglio, Manuela, Labopin, Myriam, Fröhling, Stefan, Secondino, Simona, Heinz, Jürgen, Nicolas-Virelizier, Emmanuelle, Blaise, Didier, Korenbaum, Clément, Santoro, Armando, Verbeek, Mareike, Krüger, William, Siena, Salvatore, Passweg, Jakob R, Di Nicola, Massimo, Rifón, Jose, Dreger, Peter, Koehl, Ulrike, Chabannon, Christian, Pedrazzoli, Paolo
Publicado 2020

Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature

por Koelsche, Christian, Benhamida, Jamal K., Kommoss, Felix K. F., Stichel, Damian, Jones, David T. W., Pfister, Stefan M., Heilig, Christoph E., Fröhling, Stefan, Stenzinger, Albrecht, Buslei, Rolf, Mentzel, Thomas, Baumhoer, Daniel, Ladanyi, Marc, Antonescu, Cristina R., Flucke, Uta, Gorp, Joost van, Bode-Lesniewska, Beata, Deimling, Andreas von, Mechtersheimer, Gunhild
Publicado 2021

Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia

por Horak, Peter, Uhrig, Sebastian, Witzel, Maximilian, Gil-Farina, Irene, Hutter, Barbara, Rath, Tim, Gieldon, Laura, Balasubramanian, Gnana Prakash, Pastor, Xavier, Heilig, Christoph E., Richter, Daniela, Schröck, Evelin, Ball, Claudia R., Brors, Benedikt, Braun, Christian J., Albert, Michael H., Scholl, Claudia, von Kalle, Christof, Schmidt, Manfred, Fröhling, Stefan, Klein, Christoph, Glimm, Hanno
Publicado 2020

Publisher Correction: Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia

por Horak, Peter, Uhrig, Sebastian, Witzel, Maximilian, Gil-Farina, Irene, Hutter, Barbara, Rath, Tim, Gieldon, Laura, Balasubramanian, Gnana Prakash, Pastor, Xavier, Heilig, Christoph E., Richter, Daniela, Schröck, Evelin, Ball, Claudia R., Brors, Benedikt, Braun, Christian J., Albert, Michael H., Scholl, Claudia, von Kalle, Christof, Schmidt, Manfred, Fröhling, Stefan, Klein, Christoph, Glimm, Hanno
Publicado 2021

The landscape of chromothripsis across adult cancer types

por Voronina, Natalia, Wong, John K. L., Hübschmann, Daniel, Hlevnjak, Mario, Uhrig, Sebastian, Heilig, Christoph E., Horak, Peter, Kreutzfeldt, Simon, Mock, Andreas, Stenzinger, Albrecht, Hutter, Barbara, Fröhlich, Martina, Brors, Benedikt, Jahn, Arne, Klink, Barbara, Gieldon, Laura, Sieverling, Lina, Feuerbach, Lars, Chudasama, Priya, Beck, Katja, Kroiss, Matthias, Heining, Christoph, Möhrmann, Lino, Fischer, Andrea, Schröck, Evelin, Glimm, Hanno, Zapatka, Marc, Lichter, Peter, Fröhling, Stefan, Ernst, Aurélie
Publicado 2020

NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology

por Mock, Andreas, Teleanu, Maria-Veronica, Kreutzfeldt, Simon, Heilig, Christoph E., Hüllein, Jennifer, Möhrmann, Lino, Jahn, Arne, Hanf, Dorothea, Kerle, Irina A., Singh, Hans Martin, Hutter, Barbara, Uhrig, Sebastian, Fröhlich, Martina, Neumann, Olaf, Hartig, Andreas, Brückmann, Sascha, Hirsch, Steffen, Grund, Kerstin, Dikow, Nicola, Lipka, Daniel B., Renner, Marcus, Bhatti, Irfan Ahmed, Apostolidis, Leonidas, Schlenk, Richard F., Schaaf, Christian P., Stenzinger, Albrecht, Schröck, Evelin, Hübschmann, Daniel, Heining, Christoph, Horak, Peter, Glimm, Hanno, Fröhling, Stefan
Publicado 2023

MGMT inactivation as a new biomarker in patients with advanced biliary tract cancers

por Niger, Monica, Nichetti, Federico, Casadei‐Gardini, Andrea, Morano, Federica, Pircher, Chiara, Tamborini, Elena, Perrone, Federica, Canale, Matteo, Lipka, Daniel B., Vingiani, Andrea, Agnelli, Luca, Dobberkau, Anna, Hüllein, Jennifer, Korell, Felix, Heilig, Christoph E., Pusceddu, Sara, Corti, Francesca, Droz, Michele, Ulivi, Paola, Prisciandaro, Michele, Antista, Maria, Bini, Marta, Cattaneo, Laura, Milione, Massimo, Glimm, Hanno, Köhler, Bruno C., Pruneri, Giancarlo, Hübschmann, Daniel, Fröhling, Stefan, Mazzaferro, Vincenzo, Pietrantonio, Filippo, Di Bartolomeo, Maria, de Braud, Filippo
Publicado 2022

Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer

por Scherr, Anna-Lena, Mock, Andreas, Gdynia, Georg, Schmitt, Nathalie, Heilig, Christoph E., Korell, Felix, Rhadakrishnan, Praveen, Hoffmeister, Paula, Metzeler, Klaus H., Schulze-Osthoff, Klaus, Illert, Anna L., Boerries, Melanie, Trojan, Jörg, Waidmann, Oliver, Falkenhorst, Johanna, Siveke, Jens, Jost, Philipp J., Bitzer, Michael, Malek, Nisar P., Vecchione, Loredana, Jelas, Ivan, Brors, Benedikt, Glimm, Hanno, Stenzinger, Albrecht, Grekova, Svetlana P., Gehrig, Tobias, Schulze-Bergkamen, Henning, Jäger, Dirk, Schirmacher, Peter, Heikenwalder, Mathias, Goeppert, Benjamin, Schneider, Martin, Fröhling, Stefan, Köhler, Bruno C.
Publicado 2020

Defective homologous recombination DNA repair as therapeutic target in advanced chordoma

por Gröschel, Stefan, Hübschmann, Daniel, Raimondi, Francesco, Horak, Peter, Warsow, Gregor, Fröhlich, Martina, Klink, Barbara, Gieldon, Laura, Hutter, Barbara, Kleinheinz, Kortine, Bonekamp, David, Marschal, Oliver, Chudasama, Priya, Mika, Jagoda, Groth, Marie, Uhrig, Sebastian, Krämer, Stephen, Heining, Christoph, Heilig, Christoph E., Richter, Daniela, Reisinger, Eva, Pfütze, Katrin, Eils, Roland, Wolf, Stephan, von Kalle, Christof, Brandts, Christian, Scholl, Claudia, Weichert, Wilko, Richter, Stephan, Bauer, Sebastian, Penzel, Roland, Schröck, Evelin, Stenzinger, Albrecht, Schlenk, Richard F., Brors, Benedikt, Russell, Robert B., Glimm, Hanno, Schlesner, Matthias, Fröhling, Stefan
Publicado 2019

Integrative genomic and transcriptomic analysis of leiomyosarcoma

por Chudasama, Priya, Mughal, Sadaf S., Sanders, Mathijs A., Hübschmann, Daniel, Chung, Inn, Deeg, Katharina I., Wong, Siao-Han, Rabe, Sophie, Hlevnjak, Mario, Zapatka, Marc, Ernst, Aurélie, Kleinheinz, Kortine, Schlesner, Matthias, Sieverling, Lina, Klink, Barbara, Schröck, Evelin, Hoogenboezem, Remco M., Kasper, Bernd, Heilig, Christoph E., Egerer, Gerlinde, Wolf, Stephan, von Kalle, Christof, Eils, Roland, Stenzinger, Albrecht, Weichert, Wilko, Glimm, Hanno, Gröschel, Stefan, Kopp, Hans-Georg, Omlor, Georg, Lehner, Burkhard, Bauer, Sebastian, Schimmack, Simon, Ulrich, Alexis, Mechtersheimer, Gunhild, Rippe, Karsten, Brors, Benedikt, Hutter, Barbara, Renner, Marcus, Hohenberger, Peter, Scholl, Claudia, Fröhling, Stefan
Publicado 2018

Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity

por Möhrmann, Lino, Werner, Maximilian, Oleś, Małgorzata, Mock, Andreas, Uhrig, Sebastian, Jahn, Arne, Kreutzfeldt, Simon, Fröhlich, Martina, Hutter, Barbara, Paramasivam, Nagarajan, Richter, Daniela, Beck, Katja, Winter, Ulrike, Pfütze, Katrin, Heilig, Christoph E., Teleanu, Veronica, Lipka, Daniel B., Zapatka, Marc, Hanf, Dorothea, List, Catrin, Allgäuer, Michael, Penzel, Roland, Rüter, Gina, Jelas, Ivan, Hamacher, Rainer, Falkenhorst, Johanna, Wagner, Sebastian, Brandts, Christian H., Boerries, Melanie, Illert, Anna L., Metzeler, Klaus H., Westphalen, C. Benedikt, Desuki, Alexander, Kindler, Thomas, Folprecht, Gunnar, Weichert, Wilko, Brors, Benedikt, Stenzinger, Albrecht, Schröck, Evelin, Hübschmann, Daniel, Horak, Peter, Heining, Christoph, Fröhling, Stefan, Glimm, Hanno
Publicado 2022

Sarcoma classification by DNA methylation profiling

por Koelsche, Christian, Schrimpf, Daniel, Stichel, Damian, Sill, Martin, Sahm, Felix, Reuss, David E., Blattner, Mirjam, Worst, Barbara, Heilig, Christoph E., Beck, Katja, Horak, Peter, Kreutzfeldt, Simon, Paff, Elke, Stark, Sebastian, Johann, Pascal, Selt, Florian, Ecker, Jonas, Sturm, Dominik, Pajtler, Kristian W., Reinhardt, Annekathrin, Wefers, Annika K., Sievers, Philipp, Ebrahimi, Azadeh, Suwala, Abigail, Fernández-Klett, Francisco, Casalini, Belén, Korshunov, Andrey, Hovestadt, Volker, Kommoss, Felix K. F., Kriegsmann, Mark, Schick, Matthias, Bewerunge-Hudler, Melanie, Milde, Till, Witt, Olaf, Kulozik, Andreas E., Kool, Marcel, Romero-Pérez, Laura, Grünewald, Thomas G. P., Kirchner, Thomas, Wick, Wolfgang, Platten, Michael, Unterberg, Andreas, Uhl, Matthias, Abdollahi, Amir, Debus, Jürgen, Lehner, Burkhard, Thomas, Christian, Hasselblatt, Martin, Paulus, Werner, Hartmann, Christian, Staszewski, Ori, Prinz, Marco, Hench, Jürgen, Frank, Stephan, Versleijen-Jonkers, Yvonne M. H., Weidema, Marije E., Mentzel, Thomas, Griewank, Klaus, de Álava, Enrique, Martín, Juan Díaz, Gastearena, Miguel A. Idoate, Chang, Kenneth Tou-En, Low, Sharon Yin Yee, Cuevas-Bourdier, Adrian, Mittelbronn, Michel, Mynarek, Martin, Rutkowski, Stefan, Schüller, Ulrich, Mautner, Viktor F., Schittenhelm, Jens, Serrano, Jonathan, Snuderl, Matija, Büttner, Reinhard, Klingebiel, Thomas, Buslei, Rolf, Gessler, Manfred, Wesseling, Pieter, Dinjens, Winand N. M., Brandner, Sebastian, Jaunmuktane, Zane, Lyskjær, Iben, Schirmacher, Peter, Stenzinger, Albrecht, Brors, Benedikt, Glimm, Hanno, Heining, Christoph, Tirado, Oscar M., Sáinz-Jaspeado, Miguel, Mora, Jaume, Alonso, Javier, del Muro, Xavier Garcia, Moran, Sebastian, Esteller, Manel, Benhamida, Jamal K., Ladanyi, Marc, Wardelmann, Eva, Antonescu, Cristina, Flanagan, Adrienne, Dirksen, Uta, Hohenberger, Peter, Baumhoer, Daniel, Hartmann, Wolfgang, Vokuhl, Christian, Flucke, Uta, Petersen, Iver, Mechtersheimer, Gunhild, Capper, David, Jones, David T. W., Fröhling, Stefan, Pfister, Stefan M., von Deimling, Andreas
Publicado 2021