Lipoprotein oxidation in cardiovascular disease: chief culprit or innocent bystander?

por Heinecke, Jay W.
Publicado 2006

Myeloperoxidase: A Therapeutic Target for Preventing Insulin Resistance and the Metabolic Sequelae of Obesity?

por Heinecke, Jay W., Goldberg, Ira J.
Publicado 2014

An Experimentally Robust Model of Monomeric Apolipoprotein A-I Created from a Chimera of Two X-ray Structures and Molecular Dynamics Simulations

por Segrest, Jere P., Jones, Martin K., Shao, Baohai, Heinecke, Jay W.
Publicado 2014

Testosterone replacement in hypogonadal men alters the HDL proteome but not HDL cholesterol efflux capacity

por Rubinow, Katya B., Vaisar, Tomas, Tang, Chongren, Matsumoto, Alvin M., Heinecke, Jay W., Page, Stephanie T.
Publicado 2012

Macrophage Metalloelastase (MMP-12) Deficiency Mitigates Retinal Inflammation and Pathological Angiogenesis in Ischemic Retinopathy

por Li, Jingming, Wang, Joshua J., Peng, Qisheng, Chen, Chen, Humphrey, Mary Beth, Heinecke, Jay, Zhang, Sarah X.
Publicado 2012

HDL Particle Concentration and Size Predict Incident Coronary Artery Disease Events in People with Type 1 Diabetes

por Costacou, Tina, Vaisar, Tomas, Miller, Rachel G., Davidson, W. Sean, Heinecke, Jay W., Orchard, Trevor J., Bornfeldt, Karin E.
Publicado 2023

Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway

por Pamir, Nathalie, Hutchins, Patrick, Ronsein, Graziella, Vaisar, Tomas, Reardon, Catherine A., Getz, Godfrey S., Lusis, Aldons J., Heinecke, Jay W.
Publicado 2016

ABCA1 is an extracellular phospholipid translocase

por Segrest, Jere P., Tang, Chongren, Song, Hyun D., Jones, Martin K., Davidson, W. Sean, Aller, Stephen G., Heinecke, Jay W.
Publicado 2022

Extracellular vesicles from gastric epithelial GES-1 cells infected with Helicobacter pylori promote changes in recipient cells associated with malignancy

por González, María Fernanda, Burgos-Ravanal, Renato, Shao, Baohai, Heinecke, Jay, Valenzuela-Valderrama, Manuel, Corvalán, Alejandro H., Quest, Andrew F. G.
Publicado 2022

GM-CSF driven myeloid cells in adipose tissue link weight gain and insulin resistance via formation of 2-aminoadipate

por Plubell, Deanna L., Fenton, Alexandra M., Wilmarth, Phillip A., Bergstrom, Paige, Zhao, Yuqi, Minnier, Jessica, Heinecke, Jay W., Yang, Xia, Pamir, Nathalie
Publicado 2018

Association Between Triglycerides and Incident Cognitive Impairment in Black and White Adults in the Reasons for Geographic and Racial Differences in Stroke Study

por Rosenson, Robert S., Cushman, Mary, McKinley, Emily C., Muntner, Paul, Wang, Zhixin, Vaisar, Tomas, Heinecke, Jay, Tangney, Christy, Judd, Suzanne, Colantonio, Lisandro D.
Publicado 2023

Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine model

por Palacios, Esteban, Lobos-González, Lorena, Guerrero, Simón, Kogan, Marcelo J., Shao, Baohai, Heinecke, Jay W., Quest, Andrew F. G., Leyton, Lisette, Valenzuela-Valderrama, Manuel
Publicado 2023

Unique Proteomic Signatures Distinguish Macrophages and Dendritic Cells

por Becker, Lev, Liu, Ning-Chun, Averill, Michelle M., Yuan, Wei, Pamir, Nathalie, Peng, Yufeng, Irwin, Angela D., Fu, Xiaoyun, Bornfeldt, Karin E., Heinecke, Jay W.
Publicado 2012

TLR-2/TLR-4 TREM-1 Signaling Pathway Is Dispensable in Inflammatory Myeloid Cells during Sterile Kidney Injury

por Campanholle, Gabriela, Mittelsteadt, Kristen, Nakagawa, Shunsaku, Kobayashi, Akio, Lin, Shuei-Liong, Gharib, Sina A., Heinecke, Jay W., Hamerman, Jessica A., Altemeier, William A., Duffield, Jeremy S.
Publicado 2013

Cholesterol Mass Efflux Capacity, Incident Cardiovascular Disease, and Progression of Carotid Plaque: The Multi-Ethnic Study of Atherosclerosis

por Shea, Steven, Stein, James H., Jorgensen, Neal W., McClelland, Robyn L., Tascau, Liana, Shrager, Sandi, Heinecke, Jay W., Yvan-Charvet, Laurent, Tall, Alan R.
Publicado 2019

Genetic control of the mouse HDL proteome defines HDL traits, function, and heterogeneity

por Pamir, Nathalie, Pan, Calvin, Plubell, Deanna L., Hutchins, Patrick M., Tang, Chongren, Wimberger, Jake, Irwin, Angela, Vallim, Thomas Q. de Aguiar, Heinecke, Jay W., Lusis, Aldons J.
Publicado 2019

Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes

por Shao, Baohai, Snell-Bergeon, Janet K., Pyle, Laura L., Thomas, Katie E., de Boer, Ian H., Kothari, Vishal, Segrest, Jere, Davidson, William S., Bornfeldt, Karin E., Heinecke, Jay W.
Publicado 2022

Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II

por Melchior, John T., Street, Scott E., Vaisar, Tomas, Hart, Rachel, Jerome, Jay, Kuklenyik, Zsuzsanna, Clouet-Foraison, Noemie, Thornock, Carissa, Bedi, Shimpi, Shah, Amy S., Segrest, Jere P., Heinecke, Jay W., Davidson, W. Sean
Publicado 2021

Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux

por Bedi, Shimpi, Morris, Jamie, Shah, Amy, Hart, Rachel C., Jerome, W. Gray, Aller, Stephen G., Tang, Chongren, Vaisar, Tomas, Bornfeldt, Karin E., Segrest, Jere P., Heinecke, Jay W., Davidson, W. Sean
Publicado 2022

Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture

por Vaisar, Tomáš, Hu, Jie H., Airhart, Nathan, Fox, Kate, Heinecke, Jay, Nicosia, Roberto F., Kohler, Ted, Potter, Zachary E., Simon, Gabriel M., Dix, Melissa M., Cravatt, Benjamin F., Gharib, Sina A., Dichek, David A.
Publicado 2020