Human and Plant Fungal Pathogens: The Role of Secondary Metabolites

por Scharf, Daniel H., Heinekamp, Thorsten, Brakhage, Axel A.
Publicado 2014

Heavy Metal-Induced Expression of PcaA Provides Cadmium Tolerance to Aspergillus fumigatus and Supports Its Virulence in the Galleria mellonella Model

por Bakti, Fruzsina, Sasse, Christoph, Heinekamp, Thorsten, Pócsi, István, Braus, Gerhard H.
Publicado 2018

Systems Biology of Fungal Infection

por Horn, Fabian, Heinekamp, Thorsten, Kniemeyer, Olaf, Pollmächer, Johannes, Valiante, Vito, Brakhage, Axel A.
Publicado 2012

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

por Heinekamp, Thorsten, Thywißen, Andreas, Macheleidt, Juliane, Keller, Sophia, Valiante, Vito, Brakhage, Axel A.
Publicado 2013

Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence

por Lapp, Katrin, Vödisch, Martin, Kroll, Kristin, Strassburger, Maria, Kniemeyer, Olaf, Heinekamp, Thorsten, Brakhage, Axel A.
Publicado 2014

CRISPR-Cas9-Based Discovery of the Verrucosidin Biosynthesis Gene Cluster in Penicillium polonicum

por Valente, Silvia, Piombo, Edoardo, Schroeckh, Volker, Meloni, Giovanna Roberta, Heinekamp, Thorsten, Brakhage, Axel A., Spadaro, Davide
Publicado 2021

Pyomelanin Formation in Aspergillus fumigatus Requires HmgX and the Transcriptional Activator HmgR but Is Dispensable for Virulence

por Keller, Sophia, Macheleidt, Juliane, Scherlach, Kirstin, Schmaler-Ripcke, Jeannette, Jacobsen, Ilse D., Heinekamp, Thorsten, Brakhage, Axel A.
Publicado 2011

Prediction and validation of host-pathogen interactions by a versatile inference approach using Aspergillus fumigatus as a case study

por Balkenhol, Johannes, Bencurova, Elena, Gupta, Shishir K, Schmidt, Hella, Heinekamp, Thorsten, Brakhage, Axel, Pottikkadavath, Aparna, Dandekar, Thomas
Publicado 2022

Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway

por Thywißen, Andreas, Heinekamp, Thorsten, Dahse, Hans-Martin, Schmaler-Ripcke, Jeannette, Nietzsche, Sandor, Zipfel, Peter F., Brakhage, Axel A.
Publicado 2011

N‐Heterocyclization in Gliotoxin Biosynthesis is Catalyzed by a Distinct Cytochrome P450 Monooxygenase

por Scharf, Daniel H., Chankhamjon, Pranatchareeya, Scherlach, Kirstin, Dworschak, Jan, Heinekamp, Thorsten, Roth, Martin, Brakhage, Axel A., Hertweck, Christian
Publicado 2020

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

por Jain, Radhika, Valiante, Vito, Remme, Nicole, Docimo, Teresa, Heinekamp, Thorsten, Hertweck, Christian, Gershenzon, Jonathan, Haas, Hubertus, Brakhage, Axel A
Publicado 2011

Interference of Aspergillus fumigatus with the immune response

por Heinekamp, Thorsten, Schmidt, Hella, Lapp, Katrin, Pähtz, Vera, Shopova, Iordana, Köster-Eiserfunke, Nora, Krüger, Thomas, Kniemeyer, Olaf, Brakhage, Axel A.
Publicado 2014

The Pheromone Module SteC-MkkB-MpkB-SteD-HamE Regulates Development, Stress Responses and Secondary Metabolism in Aspergillus fumigatus

por Frawley, Dean, Stroe, Maria C., Oakley, Berl R., Heinekamp, Thorsten, Straßburger, Maria, Fleming, Alastair B., Brakhage, Axel A., Bayram, Özgür
Publicado 2020

The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins

por Xu, Rui, Lou, Yanyan, Tidu, Antonin, Bulet, Philippe, Heinekamp, Thorsten, Martin, Franck, Brakhage, Axel, Li, Zi, Liégeois, Samuel, Ferrandon, Dominique
Publicado 2022

Activity and Safety of Inhaled Itraconazole Nanosuspension in a Model Pulmonary Aspergillus fumigatus Infection in Inoculated Young Quails

por Wlaź, Piotr, Knaga, Sebastian, Kasperek, Kornel, Wlaź, Aleksandra, Poleszak, Ewa, Jeżewska-Witkowska, Grażyna, Winiarczyk, Stanisław, Wyska, Elżbieta, Heinekamp, Thorsten, Rundfeldt, Chris
Publicado 2015

The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus

por Hillmann, Falk, Bagramyan, Karine, Straßburger, Maria, Heinekamp, Thorsten, Hong, Teresa B., Bzymek, Krzysztof P., Williams, John C., Brakhage, Axel A., Kalkum, Markus
Publicado 2016

SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus

por Jöhnk, Bastian, Bayram, Özgür, Abelmann, Anja, Heinekamp, Thorsten, Mattern, Derek J., Brakhage, Axel A., Jacobsen, Ilse D., Valerius, Oliver, Braus, Gerhard H.
Publicado 2016

Direct Visualization of Fungal Burden in Filamentous Fungus-Infected Silkworms

por Yu, Yidong, Wolf, Ann-Katrin, Thusek, Sina, Heinekamp, Thorsten, Bromley, Michael, Krappmann, Sven, Terpitz, Ulrich, Voigt, Kerstin, Brakhage, Axel A., Beilhack, Andreas
Publicado 2021

High‐Throughput Gene Replacement in Aspergillus fumigatus

por Zhao, Can, Fraczek, Marcin G., Dineen, Lauren, Lebedinec, Ressa, Macheleidt, Juliane, Heinekamp, Thorsten, Delneri, Daniela, Bowyer, Paul, Brakhage, Axel A., Bromley, Michael
Publicado 2019

Peroxiredoxin Asp f3 Is Essential for Aspergillus fumigatus To Overcome Iron Limitation during Infection

por Brantl, Victor, Boysen, Jana M., Yap, Annie, Golubtsov, Evgeny, Ruf, Dominik, Heinekamp, Thorsten, Straßburger, Maria, Dichtl, Karl, Haas, Hubertus, Hillmann, Falk, Wagener, Johannes
Publicado 2021