Safety and immunogenicity of an AS01-adjuvanted varicella zoster virus subunit candidate vaccine (HZ/su): A phase-I, open-label study in Japanese adults

por Lal, Himal, Zahaf, Toufik, Heineman, Thomas C.
Publicado 2013

Varicella-Zoster Virus Infection Triggers Formation of an Interleukin-1β (IL-1β)-processing Inflammasome Complex

por Nour, Adel M., Reichelt, Mike, Ku, Chia-Chi, Ho, Min-Yin, Heineman, Thomas C., Arvin, Ann M.
Publicado 2011

Immunogenicity and safety of an adjuvanted herpes zoster subunit candidate vaccine in adults ≥ 50 years of age with a prior history of herpes zoster: A phase III, non-randomized, o...

por Godeaux, Olivier, Kovac, Martina, Shu, Daniel, Grupping, Katrijn, Campora, Laura, Douha, Martine, Heineman, Thomas C., Lal, Himal
Publicado 2017

Immunogenicity and Safety of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults Previously Vaccinated with a Live-Attenuated Herpes Zoster Vaccine: A Phase III, Group-Matc...

por Grupping, Katrijn, Campora, Laura, Douha, Martine, Heineman, Thomas C, Klein, Nicola P, Lal, Himal, Peterson, James, Oostvogels, Lidia
Publicado 2017

Immunogenicity and Safety of the HZ/su Adjuvanted Herpes Zoster Subunit Vaccine in Adults Previously Vaccinated With a Live Attenuated Herpes Zoster Vaccine

por Grupping, Katrijn, Campora, Laura, Douha, Martine, Heineman, Thomas C, Klein, Nicola P, Lal, Himal, Peterson, James, Vastiau, Ilse, Oostvogels, Lidia
Publicado 2017

Immunogenicity and Safety of an Adjuvanted Herpes Zoster Subunit Vaccine Coadministered With Seasonal Influenza Vaccine in Adults Aged 50 Years or Older

por Schwarz, Tino F, Aggarwal, Naresh, Moeckesch, Beate, Schenkenberger, Isabelle, Claeys, Carine, Douha, Martine, Godeaux, Olivier, Grupping, Katrijn, Heineman, Thomas C, Fauqued, Marta Lopez, Oostvogels, Lidia, Van den Steen, Peter, Lal, Himal
Publicado 2017

Analysis of a Phase 2b Study of GEN-003, a Genital Herpes Immunotherapy, Showed Significant Reductions in Viral Shedding and Lesion Rate Vs Placebo

por Heineman, Thomas C, Bernstein, David, Wald, Anna, Van Wagoner, Nicholas, Leone, Peter, Mayer, Kenneth, Lucksinger, Gregg, Win, Sandra, Koltun, William, Desai, Nisha, Oliphant, Thomas, Natenshon, Andrew, McNeil, Lisa K, Flechtner, Jessica B, Hetherington, Seth
Publicado 2017

Safety and Immunogenicity of an Adjuvanted Herpes Zoster Subunit Candidate Vaccine in HIV-Infected Adults: A Phase 1/2a Randomized, Placebo-Controlled Study

por Berkowitz, Elchonon M., Moyle, Graeme, Stellbrink, Hans-Jürgen, Schürmann, Dirk, Kegg, Stephen, Stoll, Matthias, El Idrissi, Mohamed, Oostvogels, Lidia, Heineman, Thomas C., Brockmeyer, Norbert, deJesus, Edwin, Esser, Stefan, Hawkins, Trevor, Lalezari, Jacob, Orkin, Chloe, Schneider, Stefan
Publicado 2015

Immunogenicity and safety of the adjuvanted recombinant zoster vaccine in patients with solid tumors, vaccinated before or during chemotherapy: A randomized trial

por Vink, Peter, Delgado Mingorance, Ignacio, Maximiano Alonso, Constanza, Rubio‐Viqueira, Belen, Jung, Kyung Hae, Rodriguez Moreno, Juan Francisco, Grande, Enrique, Marrupe Gonzalez, David, Lowndes, Sarah, Puente, Javier, Kristeleit, Hartmut, Farrugia, David, McNeil, Shelly A., Campora, Laura, Di Paolo, Emmanuel, El Idrissi, Mohamed, Godeaux, Olivier, López‐Fauqued, Marta, Salaun, Bruno, Heineman, Thomas C., Oostvogels, Lidia
Publicado 2019

Immune Responses to a Recombinant Glycoprotein E Herpes Zoster Vaccine in Adults Aged 50 Years or Older

por Cunningham, Anthony L, Heineman, Thomas C, Lal, Himal, Godeaux, Olivier, Chlibek, Roman, Hwang, Shinn-Jang, McElhaney, Janet E, Vesikari, Timo, Andrews, Charles, Choi, Won Suk, Esen, Meral, Ikematsu, Hideyuki, Choma, Martina Kovac, Pauksens, Karlis, Ravault, Stéphanie, Salaun, Bruno, Schwarz, Tino F, Smetana, Jan, Abeele, Carline Vanden, Van den Steen, Peter, Vastiau, Ilse, Weckx, Lily Yin, Levin, Myron J
Publicado 2018

Medical conditions at enrollment do not impact efficacy and safety of the adjuvanted recombinant zoster vaccine: a pooled post-hoc analysis of two parallel randomized trials

por Oostvogels, Lidia, Heineman, Thomas C., Johnson, Robert W., Levin, Myron J., McElhaney, Janet E., Van den Steen, Peter, Zahaf, Toufik, Dagnew, Alemnew F., Chlibek, Roman, Diez-Domingo, Javier, Gorfinkel, Iris S., Hervé, Caroline, Hwang, Shinn-Jang, Ikematsu, Hideyuki, Kalema, George, Lal, Himal, McNeil, Shelly A., Mrkvan, Tomas, Pauksens, Karlis, Smetana, Jan, Watanabe, Daisuke, Weckx, Lily Yin, Cunningham, Anthony L.
Publicado 2019

149. Immunogenicity, Safety, and Post-hoc Efficacy Assessment of the Adjuvanted Recombinant Zoster Vaccine in Adults with Hematologic Malignancies: A Phase 3, Randomized Clinical T...

por Dagnew, Alemnew F, Ilhan, Osman, Lee, Won-Sik, Woszczyk, Dariusz, Kwak, Jae-Yong, Bowcock, Stella, Sohn, Sang Kyun, Rodriguez Macías, Gabriela, Chiou, Tzeon-Jye, Quiel, Dimas, Aoun, Mickael, Matilla, Maria Belen Navarro, De La Serna, Javier, Milliken, Samuel, Murphy, John, McNeil, Shelly A, Salaun, Bruno, Paolo, Emmanuel Di, Campora, Laura, López-Fauqued, Marta, El Idrissi, Mohamed, Schuind, Anne, Heineman, Thomas C, Van Den Steen, Peter, Oostvogels, Lidia
Publicado 2018

Adjuvanted recombinant zoster vaccine in adult autologous stem cell transplant recipients: polyfunctional immune responses and lessons for clinical practice

por Stadtmauer, Edward A., Sullivan, Keith M., El Idrissi, Mohamed, Salaun, Bruno, Alonso Alonso, Aránzazu, Andreadis, Charalambos, Anttila, Veli-Jukka, Bloor, Adrian JC, Broady, Raewyn, Cellini, Claudia, Cuneo, Antonio, Dagnew, Alemnew F., Di Paolo, Emmanuel, Eom, HyeonSeok, González-Rodríguez, Ana Pilar, Grigg, Andrew, Guenther, Andreas, Heineman, Thomas C., Jarque, Isidro, Kwak, Jae-Yong, Lucchesi, Alessandro, Oostvogels, Lidia, Polo Zarzuela, Marta, Schuind, Anne E., Shea, Thomas C., Sinisalo, Ulla Marjatta, Vural, Filiz, Yáñez San Segundo, Lucrecia, Zachée, Pierre, Bastidas, Adriana
Publicado 2021

Immunogenicity and Safety of the Adjuvanted Recombinant Zoster Vaccine in Chronically Immunosuppressed Adults Following Renal Transplant: A Phase 3, Randomized Clinical Trial

por Vink, Peter, Ramon Torrell, Josep Maria, Sanchez Fructuoso, Ana, Kim, Sung-Joo, Kim, Sang-il, Zaltzman, Jeff, Ortiz, Fernanda, Campistol Plana, Josep Maria, Fernandez Rodriguez, Ana Maria, Rebollo Rodrigo, Henar, Campins Marti, Magda, Perez, Rafael, González Roncero, Francisco Manuel, Kumar, Deepali, Chiang, Yang-Jen, Doucette, Karen, Pipeleers, Lissa, Agüera Morales, Maria Luisa, Rodriguez-Ferrero, Maria Luisa, Secchi, Antonio, McNeil, Shelly A, Campora, Laura, Di Paolo, Emmanuel, El Idrissi, Mohamed, López-Fauqued, Marta, Salaun, Bruno, Heineman, Thomas C, Oostvogels, Lidia
Publicado 2020