Antiviral and Immunomodulatory Effects of Pelargonium sidoides DC. Root Extract EPs® 7630 in SARS-CoV-2-Infected Human Lung Cells

por Papies, Jan, Emanuel, Jackson, Heinemann, Nicolas, Kulić, Žarko, Schroeder, Simon, Tenner, Beate, Lehner, Martin D., Seifert, Georg, Müller, Marcel A.
Publicado 2021

Corrigendum: Antiviral and Immunomodulatory Effects of Pelargonium sidoides DC. Root Extract EPs(®) 7630 in SARS-CoV-2-Infected Human Lung Cells

por Papies, Jan, Emanuel, Jackson, Heinemann, Nicolas, Kulić, Žarko, Schroeder, Simon, Tenner, Beate, Lehner, Martin D., Seifert, Georg, Müller, Marcel A.
Publicado 2021

In vitro and in vivo effects of Pelargonium sidoides DC. root extract EPs(®) 7630 and selected constituents against SARS-CoV-2 B.1, Delta AY.4/AY.117 and Omicron BA.2

por Emanuel, Jackson, Papies, Jan, Galander, Celine, Adler, Julia M., Heinemann, Nicolas, Eschke, Kathrin, Merz, Sophie, Pischon, Hannah, Rose, Ruben, Krumbholz, Andi, Kulić, Žarko, Lehner, Martin D., Trimpert, Jakob, Müller, Marcel A.
Publicado 2023

Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection

por Mhlekude, Baxolele, Postmus, Dylan, Stenzel, Saskia, Weiner, January, Jansen, Jenny, Zapatero-Belinchón, Francisco J., Olmer, Ruth, Richter, Anja, Heinze, Julian, Heinemann, Nicolas, Mühlemann, Barbara, Schroeder, Simon, Jones, Terry C., Müller, Marcel A., Drosten, Christian, Pich, Andreas, Thiel, Volker, Martin, Ulrich, Niemeyer, Daniela, Gerold, Gisa, Beule, Dieter, Goffinet, Christine
Publicado 2023

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals

por Gassen, Nils C., Papies, Jan, Bajaj, Thomas, Emanuel, Jackson, Dethloff, Frederik, Chua, Robert Lorenz, Trimpert, Jakob, Heinemann, Nicolas, Niemeyer, Christine, Weege, Friderike, Hönzke, Katja, Aschman, Tom, Heinz, Daniel E., Weckmann, Katja, Ebert, Tim, Zellner, Andreas, Lennarz, Martina, Wyler, Emanuel, Schroeder, Simon, Richter, Anja, Niemeyer, Daniela, Hoffmann, Karen, Meyer, Thomas F., Heppner, Frank L., Corman, Victor M., Landthaler, Markus, Hocke, Andreas C., Morkel, Markus, Osterrieder, Nikolaus, Conrad, Christian, Eils, Roland, Radbruch, Helena, Giavalisco, Patrick, Drosten, Christian, Müller, Marcel A.
Publicado 2021

SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression

por Niemeyer, Daniela, Stenzel, Saskia, Veith, Talitha, Schroeder, Simon, Friedmann, Kirstin, Weege, Friderike, Trimpert, Jakob, Heinze, Julian, Richter, Anja, Jansen, Jenny, Emanuel, Jackson, Kazmierski, Julia, Pott, Fabian, Jeworowski, Lara M., Olmer, Ruth, Jaboreck, Mark-Christian, Tenner, Beate, Papies, Jan, Walper, Felix, Schmidt, Marie L., Heinemann, Nicolas, Möncke-Buchner, Elisabeth, Baumgardt, Morris, Hoffmann, Karen, Widera, Marek, Thao, Tran Thi Nhu, Balázs, Anita, Schulze, Jessica, Mache, Christin, Jones, Terry C., Morkel, Markus, Ciesek, Sandra, Hanitsch, Leif G., Mall, Marcus A., Hocke, Andreas C., Thiel, Volker, Osterrieder, Klaus, Wolff, Thorsten, Martin, Ulrich, Corman, Victor M., Müller, Marcel A., Goffinet, Christine, Drosten, Christian
Publicado 2022