Lynch Syndrome-associated Mutations in MSH2 Alter DNA Repair and Checkpoint Response Functions In Vivo

por Mastrocola, Adam S, Heinen, Christopher D
Publicado 2010

Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays

por Heinen, Christopher D, Juel Rasmussen, Lene
Publicado 2012

Loss of DNA Mismatch Repair Imparts a Selective Advantage in Planarian Adult Stem Cells

por Hollenbach, Jessica P., Resch, Alissa M., Palakodeti, Dasaradhi, Graveley, Brenton R., Heinen, Christopher D.
Publicado 2011

Loss of mismatch repair promotes a direct selective advantage in human stem cells

por Madden-Hennessey, Kirby, Gupta, Dipika, Radecki, Alexander A., Guild, Caroline, Rath, Abhijit, Heinen, Christopher D.
Publicado 2022

Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways

por Taghbalout, Aziz, Du, Menghan, Jillette, Nathaniel, Rosikiewicz, Wojciech, Rath, Abhijit, Heinen, Christopher D., Li, Sheng, Cheng, Albert W.
Publicado 2019

Recommendations for application of the functional evidence PS3/BS3 criterion using the ACMG/AMP sequence variant interpretation framework

por Brnich, Sarah E., Abou Tayoun, Ahmad N., Couch, Fergus J., Cutting, Garry R., Greenblatt, Marc S., Heinen, Christopher D., Kanavy, Dona M., Luo, Xi, McNulty, Shannon M., Starita, Lea M., Tavtigian, Sean V., Wright, Matt W., Harrison, Steven M., Biesecker, Leslie G., Berg, Jonathan S.
Publicado 2019