Crystal structure of mammalian acid sphingomyelinase

por Gorelik, Alexei, Illes, Katalin, Heinz, Leonhard X., Superti-Furga, Giulio, Nagar, Bhushan
Publicado 2016

A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery

por Essletzbichler, Patrick, Sedlyarov, Vitaly, Frommelt, Fabian, Soulat, Didier, Heinz, Leonhard X, Stefanovic, Adrijana, Neumayer, Benedikt, Superti-Furga, Giulio
Publicado 2023

A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses

por Köberlin, Marielle S., Snijder, Berend, Heinz, Leonhard X., Baumann, Christoph L., Fauster, Astrid, Vladimer, Gregory I., Gavin, Anne-Claude, Superti-Furga, Giulio
Publicado 2015

Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking

por Fauster, Astrid, Rebsamen, Manuele, Willmann, Katharina L., César-Razquin, Adrian, Girardi, Enrico, Bigenzahn, Johannes W., Schischlik, Fiorella, Scorzoni, Stefania, Bruckner, Manuela, Konecka, Justyna, Hörmann, Katrin, Heinz, Leonhard X., Boztug, Kaan, Superti-Furga, Giulio
Publicado 2018

The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification

por Sedlyarov, Vitaly, Eichner, Ruth, Girardi, Enrico, Essletzbichler, Patrick, Goldmann, Ulrich, Nunes-Hasler, Paula, Srndic, Ismet, Moskovskich, Anna, Heinz, Leonhard X., Kartnig, Felix, Bigenzahn, Johannes W., Rebsamen, Manuele, Kovarik, Pavel, Demaurex, Nicolas, Superti-Furga, Giulio
Publicado 2018

A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity

por Boeszoermenyi, Andras, Bernaleau, Léa, Chen, Xudong, Kartnig, Felix, Xie, Min, Zhang, Haobo, Zhang, Sensen, Delacrétaz, Maeva, Koren, Anna, Hopp, Ann-Katrin, Dvorak, Vojtech, Kubicek, Stefan, Aletaha, Daniel, Yang, Maojun, Rebsamen, Manuele, Heinz, Leonhard X., Superti-Furga, Giulio
Publicado 2023

Accelerated waning of immune responses to a third COVID-19 vaccination in patients with immune-mediated inflammatory diseases

por Mrak, Daniel, Kartnig, Felix, Sieghart, Daniela, Simader, Elisabeth, Radner, Helga, Mandl, Peter, Göschl, Lisa, Hofer, Philipp, Deimel, Thomas, Gessl, Irina, Kain, Renate, Winkler, Stefan, Smolen, Josef S., Perkmann, Thomas, Haslacher, Helmuth, Aletaha, Daniel, Heinz, Leonhard X., Bonelli, Michael
Publicado 2023

The accelerated waning of immunity and reduced effect of booster in patients treated with bDMARD and tsDMARD after SARS-CoV-2 mRNA vaccination

por Tobudic, Selma, Simader, Elisabeth, Deimel, Thomas, Straub, Jennifer, Kartnig, Felix, Heinz, Leonhard X., Mandl, Peter, Haslacher, Helmuth, Perkmann, Thomas, Schneider, Lisa, Nothnagl, Thomas, Radner, Helga, Winkler, Florian, Burgmann, Heinz, Stiasny, Karin, Novacek, Gottfried, Reinisch, Walter, Aletaha, Daniel, Winkler, Stefan, Blüml, Stephan
Publicado 2023

SLC38A9 is a component of the lysosomal amino acid-sensing machinery that controls mTORC1

por Rebsamen, Manuele, Pochini, Lorena, Stasyk, Taras, de Araújo, Mariana E. G., Galluccio, Michele, Kandasamy, Richard K., Snijder, Berend, Fauster, Astrid, Rudashevskaya, Elena L., Bruckner, Manuela, Scorzoni, Stefania, Filipek, Przemyslaw A., Huber, Kilian V. M., Bigenzahn, Johannes, Heinz, Leonhard X., Kraft, Claudine, Bennett, Keiryn L., Indiveri, Cesare, Huber, Lukas A., Superti-Furga, Giulio
Publicado 2015

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

por Heinz, Leonhard X., Baumann, Christoph L., Köberlin, Marielle S., Snijder, Berend, Gawish, Riem, Shui, Guanghou, Sharif, Omar, Aspalter, Irene M., Müller, André C., Kandasamy, Richard K., Breitwieser, Florian P., Pichlmair, Andreas, Bruckner, Manuela, Rebsamen, Manuele, Blüml, Stephan, Karonitsch, Thomas, Fauster, Astrid, Colinge, Jacques, Bennett, Keiryn L., Knapp, Sylvia, Wenk, Markus R., Superti-Furga, Giulio
Publicado 2015

TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9

por Heinz, Leonhard X., Lee, JangEun, Kapoor, Utkarsh, Kartnig, Felix, Sedlyarov, Vitaly, Papakostas, Konstantinos, César-Razquin, Adrian, Essletzbichler, Patrick, Goldmann, Ulrich, Stefanovic, Adrijana, Bigenzahn, Johannes W., Scorzoni, Stefania, Pizzagalli, Mattia D., Bensimon, Ariel, Müller, André C., King, F. James, Li, Jun, Girardi, Enrico, Mbow, M. Lamine, Whitehurst, Charles E., Rebsamen, Manuele, Superti-Furga, Giulio
Publicado 2020

Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial

por Mrak, Daniel, Sieghart, Daniela, Simader, Elisabeth, Tobudic, Selma, Radner, Helga, Mandl, Peter, Göschl, Lisa, Koblischke, Maximilian, Hommer, Nikolaus, Wagner, Angelika, Mayer, Margareta, Schubert, Lorenz, Hartl, Lukas, Kozbial, Karin, Hofer, Philipp, Kartnig, Felix, Hummel, Thomas, Kerschbaumer, Andreas, Deimel, Thomas, Puchner, Antonia, Gudipati, Venugopal, Thalhammer, Renate, Munda, Petra, Uyanik-Ünal, Keziban, Zuckermann, Andreas, Novacek, Gottfried, Reiberger, Thomas, Garner-Spitzer, Erika, Reindl-Schwaighofer, Roman, Kain, Renate, Winkler, Stefan, Smolen, Josef S., Stiasny, Karin, Fischer, Gottfried F., Perkmann, Thomas, Haslacher, Helmuth, Zeitlinger, Markus, Wiedermann, Ursula, Aberle, Judith H., Aletaha, Daniel, Heinz, Leonhard X., Bonelli, Michael
Publicado 2022